PředmětyPředměty(verze: 945)
Předmět, akademický rok 2023/2024
   Přihlásit přes CAS
Pathological Physiology I - FGP028
Anglický název: Pathological Physiology I
Zajišťuje: Ústav patologické fyziologie (15-330)
Fakulta: Lékařská fakulta v Hradci Králové
Platnost: od 2023
Semestr: zimní
Body: 0
E-Kredity: 6
Způsob provedení zkoušky: zimní s.:
Rozsah, examinace: zimní s.:42/36, Z [HS]
Počet míst: neomezen
Minimální obsazenost: neomezen
4EU+: ne
Virtuální mobilita / počet míst pro virtuální mobilitu: ne
Kompetence:  
Stav předmětu: vyučován
Jazyk výuky: angličtina
Způsob výuky: prezenční
Způsob výuky: prezenční
Úroveň:  
Garant: prof. MUDr. Zuzana Kubová, CSc.
Prerekvizity : {General Medicine 1st year}, FGP012, FGP014, FGP016
Neslučitelnost : FV10023
Záměnnost : FA0106040, FV10023
Je korekvizitou pro: FGP029
Ve slož. prerekvizitě: FG10050, FG10051, FG10052, FG10054, FG10055, FG10056, FG10057, FG10058, FG10059, FG10060, FG10061, FG10062, FG10063, FG10064, FG10065, FG10066, FG10067, FG10068, FG10076, FG10077, FG10078, FG10079, FG10080, FG10081, FG10092, FG10093, FG10094, FG10095, FG10097
Anotace - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)
Pathological physiology is a preclinical subject that deals with etiology (causes) and pathogenesis (development) of body dysfunctions. It aims to understanding of mechanisms that can influence the origin and course of diseases, which is necessary for correct causal and individualized treatment. In the first term students are taught general principles of diseases and their effect on organism. A part of the study is devoted to states that accompany the specific diseases e.g. effects of inflammation, hypoxia, and internal environment disorders. Further students gain a comprehensive overview of etiology and pathogenesis of blood, cardiovascular and respiratory diseases. Practical part of the study is oriented mainly to acquiring knowledge of registration and description of ECG. In Computer spirometry practical class the students get information about most frequent spirometry findings in respiratory diseases.
Vstupní požadavky - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)

prerequisites – compulsory subjects of 1st year GM, Biology II, Biochemistry II, Physiology II.  

Cíl předmětu - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)

1.      ability to explain general principles and consequences of impaired body functions

2.      knowledge of pathophysiology of cardiovascular, respiratory and blood diseases

3.      description of basic parameters of ECG and distinguishing pathological from physiological findings

4.      distinguishing normal spirometry recording from findings typical for obstructive and restrictive respiratory disorders 

Požadavky ke zkoušce - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)

Credit:

a) presence in practical classes/seminars

-         mandatory 100% participation, tolerance of a maximum of one excused absence

-         in case of more than one absence it is necessary to replace the seminar/practical class (the way of a replacement is determined by the teacher of the particular seminar/practical class, usually it is oral examination of the issue)

 

b) tests

description of two ECG curves when each must be evaluated with the worst grade 3 (in the range 1(excellent) – 4 (fail))

passing all the ongoing tests with the worst grade 3

-         in case of non-participation, an apology before the time of the test is required and the test must be taken on an alternative date

-         student is allowed to one excuse during the whole year

-         non-excused absence is evaluated wit grade 4

 

Possibility of consultations after previous agreement with teachers of Department of Pathological Physiology

Sylabus - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)

Lectures

Lecturers

  • prof. MUDr. Miroslav Kuba, DSc.
  • prof. MUDr. Zuzana Kubová, CSc.
  • MUDr. Marie Chutná
  • MUDr. Lenka Miščík Ramešová

 

  1. Organism and Environment, Adaptation. Etiology and Pathogenesis. Health Versus Disease. Clinical and Biological /Somatic/Death. (Kuba)
  2. Alterations in Fluid Volume. Disorders of Osmolarity, Etiology and Pathogenesis of Oedema. Hyponatremia, Hypernatremia. (Kubová)
  3. Hypokalemia, Hyperkalemia. Acidosis. Alkalosis(Kubová)
  4. Hypersensitivity reactions. Allergies. Autoimmune disorders. Post-transplantation responses. Immunodeficiencies. (Chutná)
  5. Disorders of Calcium and Phosphorus Metabolism, Magnesium Imbalances. Osteoporosis, Osteomalacia, Renal Osteodystrophy. Pathophysiology of Cramps. (Kuba) TEST - homeostasis disorders. (Kubová)
  6. Disorders of Peripheral Circulation. Syncope. Circulatory Shock. Thrombophilic states. DIC. (Kubová) RETAKE TEST.
  7. Blood Transfusion, Complications, Erythroblastosis Fetalis. Abnormalities of Haemostasias and Coagulation. (Kuba)
  8. Pulmonary Circulation, Ventilation/Perfusion Ratio. Gas Diffusion Disorders. Obstructive Respiratory Diseases. Restrictive Pulmonary Diseases. (Kubová)
  9. Pulmonary Hypertension, Pulmonary Oedema. ARDS. Respiratory Failure. Hypoxia. Hyperoxia, Hyperbaria, Decompression. (Kubová) TEST - haemostasis disorders. (Kuba)
  10. Dyslipoproteinemia. Endothelial Dysfunction. Effects of Nitric oxide. Arteriosclerosis. (Kubová) RETAKE TEST.
  11. Ischemic Heart Disease. Myocardial Infarction and its Complications. Acquired Valvular Heart Disease. Congenital Heart Defects. (Kuba)
  12. Heart Failure - Etiology and Pathogenesis. Compensatory Mechanisms in Heart Diseases. (Kuba)
  13. Arterial Hypertension - Etiology and Pathogenesis. Arterial Hypotension. (Kuba) TEST - pathophysiology of the cardiovascular system. (Kuba)
  14. Bone Marrow Depression. Leukemia, Lymphoma. Myeloma. (Miščík Ramešová) RETAKE TEST.

 

Practical classes and seminars

Teachers

  • prof. MUDr. Miroslav Kuba, DSc.
  • prof. MUDr. Zuzana Kubová, CSc.
  • MUDr. Jana Langrová, Ph.D.
  • MUDr. Jana Szanyi, Ph.D.
  • MUDr. Marie Chutná
  • MUDr. Lenka Miščík Ramešová

 Seminars

  1. Introduction to practical classes. Neoplasia, Neoplasm-Host Interaction (Effects).
  2. Inflammation. Sepsis. SIRS. Fever. Hyperthermia. Hypothermia and reaction of organism to cold.  
  3. Stress, General Adaptation Syndrome, Psychosomatic Diseases. 
  4. Pathophysiology of Pain.
  5. Anemias - classification, consequences. Polycythemia. Microscopic findings in peripheral blood. 

 Practical courses

  1. ECG I - description
  2. ECG II - description.
  3. ECG III - practice.
  4. ECG IV - practice, self-ECG recordings.
  5. ECG V - ECG TEST
  6. Computer spirometry - recordings and evaluation. 1/2 group; Bicycle ergometry - adaptation of the cardio-vascular system to a physical load. 1/2 group
  7. Bicycle ergometry - adaptation of the cardio-vascular system to a physical load. 1/2 group; Computer spirometry - recordings and evaluation. 1/2 group
Literatura - angličtina
Poslední úprava: Lenka Kořínková (14.09.2023)

Compulsory literature

  1. Kuba, M., Kubová, Z.  Pathophysiology - Basic overview for medical students (revised (only electronic) version)
 
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