Selected Chapters from Molecular Pathology and Translation Medicine - EDPLB0011

• Anglický název: Selected Chapters from Molecular Pathology and Translation Medicine
• Zajišťuje: Oddělení vědy a výzkumu (14-260)
• Fakulta: Lékařská fakulta v Plzni
• Platnost: od 2023
• Semestr: letní
• Body: 0
• E-Kredity: 0
• Způsob provedení zkoušky: letní s.:
• Rozsah, examinace: letní s.:4/0, Z [HS]
• Počet míst: neurčen / neurčen (neurčen)
• Minimální obsazenost: neomezen
• 4EU+: ne
• Virtuální mobilita / počet míst pro virtuální mobilitu: ne
• Stav předmětu: vyučován
• Jazyk výuky: angličtina
• Způsob výuky: prezenční
• Způsob výuky: prezenční
• Garant: doc. MUDr. Marie Ludvíková, Ph.D.

Anotace

Poslední úprava: Mgr. Barbora Stachová (06.05.2024)

The aim of the course is to acquaint postgraduate students with the latest knowledge about molecular basis of
human diseases, especially cancer. Attention will be paid in particular to epigenetic processes and their impacts
on neoplastic transformation and progression of tumours and selected nonneoplastic diseases. Translation of
new knowledge of disease processes, diagnostic or treatment techniques into routine clinical practice will be also
mentioned.

Literatura

Poslední úprava: Mgr. Barbora Stachová (06.05.2024)

1. Kumar V, Abbas AK, Aster JC: Pathologic Basis of Disease - 9th Edition, Elsevier - Saunders 2015

ISBN-13: 978-0323266161; ISBN-10: 0323266169

2. Coleman WB, Tsongalis GJ: Molecular Pathology: The Molecular Basis of Human Disease - 2nd Edition, Elsevier - Academic Press 2017

ISBN: 9780128027615, 9780128040706

3.Tollefsbol T: Handbook of Epigenetics: The New Molecular and Medical Genetics - 2nd Edition, Elsevier Academic Press 2011

ISBN-13: 978-0123757098; ISBN-10: 0123757096

Sylabus

Poslední úprava: Mgr. Barbora Stachová (06.05.2024)

In connection with sequencing of human genome and the other discoveries in biology there is an expansion of knowledge about molecular basis of human diseases, especially cancer. Molecular Pathology is the study of disease at the molecular level. Translational Medicine is a rapidly growing discipline in biomedical research that aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Molecular basis of cancer, epigenetic changes cooperating with genetic alterations to drive the cancer phenotype („Hallmarks of Cancer“) and some examples of translational research in human cancer will be mentioned during the course.