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Poslední úprava: Lenka Kostohryzová (01.08.2023)
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Poslední úprava: Lenka Kostohryzová (01.08.2023)
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Poslední úprava: Stanislava Palowska (14.09.2021)
The following reference books will be indisposition for the course attendees:
1. Chatu: The Hands-on Guide to Clinical Pharmacology ISBN-13: 978-1405191951
2. Ebadi: Desk Reference of Clinical Pharmacology ISBN-13: 978-1420047431
3. Wecker, Lynn : Brody's human pharmacology :molecular to clinical.
Philadelphia, Mosby Elsevier, 5th ed. ISBN 978-0-323-05374-7
4. Hyacinth Martin: Clinical Decision Making: Case Studies in Pharmacology ISBN-13: 978-1401835217
5. A textbook of clinical pharmacology and therapeutics / London : Hodder
Arnold, 2008. 5th ed. ISBN 978-0340900468
6. Clinical pharmacology / Bennett, P. N. Edinburgh ; New York : Churchill
Livingstone, 10th ed. ISBN 9780443102448
7. Applying medication math skills : a dimensional analysis approach / Karen Clement-O'Brien, Gary M. Lawler.. Albany : Delmar Publishers, c1999.
8. Applied therapeutics : the clinical use of drugs / edited by Mary Anne Koda-Kimble ... [et al.].. Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, c2009. |
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Poslední úprava: Stanislava Palowska (14.09.2021)
The formal examination is not applicable after this course. |
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Poslední úprava: Lenka Kostohryzová (01.08.2023)
Syllabus - Clinical Pharmacology
The Optional Subject is mainly recommended to 5th year and above students of Medicine
Organized by: Department of Medical Chemistry and Clinical Biochemistry, Division of Clinical Pharmacology. All interested may contact: MUDr. Hundie Tesfaye, Ph.D. on ext. Tel. 5656, Motol Hospital Capacity: max. 10 students/group The Optional Subject is scheduled to take place from 25. 3. - 29. 3. 2024 usually starting at 14:00 and lasting 3-4 hours for five consecutive working days. Location: 2nd Floor, G (Pediatric part of the hospital building).
During the study of preclinical compulsory courses, the medical student is hardly engaged in patient management or confronted with the real clinical problem. Pharmacology is one of the basic subjects included in mandatory preclinical subjects, where the student mainly works hard to overcome anatomy of drugs and classes. Therefore, the course offered now is aiming to help the shortly graduating future physicians how to practice rational pharmacotherapy. The course is limited to few students to work in small group after consecutive lectures. After attending the course supported by interactive discussion and case problem solving, the student is expected to have better knowledge of modern aspects of pharmacokinetics and its clinical importance, challenges associated to clinical trials and good clinical practice, problem of generics versus patented drugs, drugs prescription in special populations, importance of therapeutic drug monitoring and rational pharmacotherapy. The overall scope of the course is to emphasize the need of individual approach to help achieving quality care for patients complying with the evidence-based medicine. Day 1. (25.3.2024) Core lectures 1/ Introduction to Clinical Pharmacology 2/ Good Clinical practice 3/ Phases of Clinical trials in human subjects I-IV and ethical challenges 4/ Pharmaceutical aspects of drugs and clinical importance 5/ Adverse drug reactions, role of pharmacovigilance Day 2. (26.3.2024) Lecture + Work-shop Standard operation procedures during drug prescription/good prescribing practice. Day 3. (27.3.2024) Lecture + Work-shop Special population PK/PD and clinical importance Day 4. (28.3.2024) Lecture + Work-shop Drug-drug interaction risk, PK/PD and toxicological significances Day 5. (29.3.2024) Lecture + Work-shop Importance and methods of therapeutic drug concentration monitoring in biological specimen
Lectures on days 2-5 will be followed by workshops aiming at interactive discussion and case-supported learning.
Terms and conditions to get course attendance credits: Attendance of minimum 4 out of 5 days or 3 out of 5 days provided that an attendee must perform pharmacological analysis of 4 model clinical cases including appropriate resolution and recommendations. N.B.: International students, who attended the course as complementary to Erasmus programme, must take examination composed of triple of questions only in case they request classified grading marks.
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