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Poslední úprava: HABET (02.11.2012)
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Poslední úprava: MUDr. Jakub Hurych, Ph.D. (25.10.2022)
The condition for ending Medical Microbiology II is passing the oral examination. It can be done if the student obtain the credit for winter semester. The condition for granting credit is on the page of Department of Medical Microbiology (attandence and getting points from the tests).
Credit test. Three single choice tests are written, each has 10 questions.Test duration is 10 min. To receive credits, you must obtain a total of min. 20 points (in the sum of all partial tests, i.e. out of 30 possible points). Alternative dates for intermediate tests will not be possible. If the student does not meet the conditions, he/she has the opportunity to succeed in the comprehensive remedial test in the credit week. The test will contain 30 questions, the minimum score is 24 points.Terms:
Examination Rules for Medical Microbiology 1) Announcement of Exam Dates Exam dates will be announced on SIS during the week 9 of the winter semester at the latest. All exam dates for the winter examination period will be announced, including:
Other additional dates will be announced within the week 9 of the summer semester at the latest, for the following periods:
Once the additional examination dates are listed, the amount of all examination dates for the exam of Medical Microbiology will be final. It will not be possible to request examination outside of these specific dates, even in cases where a student did not use all exam attempts. In conclusion, it should be noted that it is possible to complete the regular examination only until the end of the examination period of the summer semester (usually until 30.6.), and re-examination two weeks before the start of the next academic year (usually until 17.9.). 2) Rules for registering for the exam and cancellation The start of registration for examination dates will be listed on SIS and will vary between individual groupings of examination dates.
A student will be allowed to take the exam only when he/she is registered for an exam date on SIS and all requisites necessary for the examination are met. Registration for an exam is not conditioned by obtaining the credit. Nevertheless, taking the exam is limited by obtaining the credit from Medical Microbiology II which is given in the same academic year as the exam takes place. Registration for an examination date will be possible until 1 day prior to the particular date. Cancellation will be allowed to be done max. 48 hours prior to the date of the exam. Registration for the 2nd re-examination (i.e., third attempt) cannot be done via SIS, but a student is requested to contact the secretariat of the Department of Medical Microbiology directly to get registered. 3) Failure to turn out and apology The student who fails to turn up for the exam that he/she registered for and he/she did not apologize beforehand, he/she is not classified, but the attempt is lost (Study and Exam rules, point 8.14). A student must apologise to the Head of the department (or to his deputy) in writing or by email, giving a reason for their no show. 4) Re-examination A student can take an examination for three times as a maximum, i.e. the student is entitled to undergo two re-examinations. However, if the student does not exploit the options within the set of examination dates, this does not entitled him/her to a special date of examination to be apponted for him/her. No “Dean terms” are allowed. |
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Poslední úprava: Romana Laušerová (22.05.2019)
Required (compulsory) textbooks: Murray P. et al. Medical Microbiology, Elsevier Books, 2015 Melter O. and Castelhano R. MicroBook – Clinical Microbiology for Medical Students, 2019
Recommended (optional) textbooks: Microbiology, Lippincott´s Illustrated Reviews, Lippincott Williams and Wilkins, 2012 Mims´ Medical Microbiology and Immunology, Elsevier, 2018
Recommended (optional) practicals: Melter O. and Malmgren Annika, Principles and Practicals in Medical Microbiology, 2014 |
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Poslední úprava: Romana Laušerová (09.03.2020)
I. General Microbiology (22 questions) 1. Bacterial cell structure. Bacterial spore. 2. Structure and classification of viruses. 3. Cell wall composition of G+ and G- bacteria. Endotoxin. 4. Capsule and other surface components. Biofilm. 5. Exotoxins and their classification according to their mechanism and site of action. 6. Bacterial factors of pathogenicity. 7. Pathogenesis of viral infections. 8. Bacterial genome and its plasticity. Mobile genetic elements. 9. Classification of antibiotics according to their mechanism of action. 10. Mechanisms of resistance to antibiotics (incl. MRSA, VRE, betalactamases). 11. Principles of rational antibiotic therapy. 12. Penicillins. 13. Cephalosporins and carbapenems. 14. Glycopeptides. Oxazolidinons (linezolid). 15. Macrolides and linkosamides. Tetracyclines including tigecycline. Chloramphenicol. 16. Aminoglycosides. Polypeptide antibiotics (polymyxin). 17. Quinolons. 18. Co-trimoxazole. Metronidazole. Nitrofurantoin. 19. Antituberculotics. 20. Antiviral therapy. 21. Antifungal therapy. 22. Side effects of antibiotic therapy.
II. Special virology and mycology (17 questions) 23. Herpesviruses - HSV1, HSV2 and varicella zoster virus. 24. Herpesviruses - EBV, cytomegalovirus and HHV-6. 25. Influenza viruses. 26. Mumps virus. Measles virus. 27. Rubella virus and parvovirus B19. 28. Lyssavirus. 29. Adenoviruses. 30. Rotaviruses. Caliciviruses. 31. Polioviruses and other enteroviruses. 32. Tick-borne encephalitis virus and other flaviviruses (except for HCV). 33. Papilomaviruses. Human pathogenic poxviruses. 34. RSV, parainfluenza viruses, coronaviruses, rhinoviruses. 35. Hepatitis viruses. 36. Virus HIV and other retroviruses. 37. Candida. Dermatophytes. 38. Aspergillus. Zygomycetes. 39. Cryptococcus. Pneumocystis.
III. Special bacteriology (32 questions) 40. Streptococcus pyogenes. 41. Viridans streptococci (S. pneumoniae, oral streptococci). 42. Beta haemolytic streptococci other than S. pyogenes. 43. Enterococci. 44. Staphylococcus aureus. 45. Coagulase negative staphylococci. 46. Neisseria meningitidis. 47. Neisseria gonorrhoeae. 48. Brucella species and Francisella tularensis. Legionella pneumophila. 49. Bordetella species. 50. Haemophilus influenzae and other Haemophilus species. 51. Listeria monocytogenes. 52. Corynebacterium diphteriae and other corynebacteria. 53. Escherichia coli. Shigella species. 54. Salmonella species (Typhi, Enteritidis and other serotypes). 55. Klebsiella, Enterobacter, Serratia, Proteus. 56. Yersinia species. 57. Vibrio cholerae and other Vibrio species. 58. Campylobacter jejuni. Helicobacter pylori. 59. Pseudomonas aeruginosa and other G- nonfermenters. 60. Mycobacterium tuberculosis. M. leprae. Atypical mycobacteria. 61. Anaerobes (other than clostridia). 62. Actinomycetes and Nocardia. 63. Clostridium tetani. Clostridium botulinum. 64. Clostridium difficile. 65. Clostridium perfringens and other histotoxic clostridia. 66. Bacillus anthracis and other Bacillus species. 67. Treponema pallidum. 68. Borrelia and Leptospira. 69. Rickettsia, Coxiella, Bartonella. 70. Chlamydia species. 71. Mycoplasma and Ureaplasma species.
IV. Parasitology (11 questions) 72. Trypanosomes and Leishmania. 73. Giardia. Cryptosporidium. Trichomonas. 74. Entamoeba and other ameboid protosoa. 75. Malaria parasites. 76. Toxoplasma gondii. 77. Schistosoma species. 78. Taenia species and other enteric tapeworms. 79. Echinococcus and other tissue tapeworms. 80. Enterobius and Ascaris. Other enteric nematodes. 81. Trichinella and other tissue nematodes. 82. Ectoparasites.
V. Clinical microbiology (16 questions) 83. Human microbial flora. 84. Upper respiratory tract infections. Microbiological diagnostics and antimicrobial therapy. 85. Lower respiratory tract and lung infections. Microbiological diagnostics and antimicrobial therapy. 86. Diarrheal diseases. Microbiological diagnostics and antimicrobial therapy. 87. Urinary tract infections. Microbiological diagnostics and antimicrobial therapy. 88. Sexually transmitted diseases. Microbiological diagnostics and antimicrobial therapy. 89. Aseptic neuroinfections. Microbiological diagnostics. 90. Purulent meningitis. Microbiological diagnostics and antimicrobial therapy. 91. Bloodstream infections. Sepsis. Microbiological diagnostics. 92. Nosocomial infections. Multiresistant strains. 93. Exanthematic viral infections. 94. Skin and soft tissue infections. Microbiological diagnostics and antimicrobial therapy. 95. Bone and joint infections. Microbiological diagnostics and antimicrobial therapy. 96. Infections caused by anaerobic bacteria. 97. Fetal and neonatal infections. 98. Vaccination.
VI. Microbiological methods and diagnostics (12 questions) 99. Specimen collection and transport for microbiological examination. 100. Microbiological diagnostics of bacterial infections; the use of methods of direct and indirect detection. 101. Microbiological diagnostics of viral infections; the use of methods of direct and indirect detection. 102. Microscopy in diagnostics of infectious diseases. 103. Bacterial culture. Culture media, their choice, culture conditions. 104. Methods of bacterial identification. 105. Antibiotic susceptibility testing. Result interpretation. 106. Serological methods (agglutination, ELISA, WB, immunochromatography). Their use in diagnostics of infectious diseases. 107. Molecular biology methods and their application in clinical microbiology. 108. Microbiological diagnostics of protozoan infections. 109. Microbiological diagnostics of helminth infections. 110. Microbiological diagnostics of fungal infections.
Choice of 3 questions from 3 areas 1. General microbiology + Clinical microbiology (total 39 questions) 2. Special virology and mycology + parasitology + methods and diagnostics (total 39 questions) 3. Special bacteriology (total 32 questions) |
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Poslední úprava: HABET (14.01.2014)
Medical Microbiology - 3rd year - winter semester 1) Staphylococci - Identification of staphylococcal species using biochemical identification systems. Bound and free coagulase in differentiation of coagulase positive (e.g. S. aureus) and negative staphylococci. 2) Streptococci - Colony morphology of clinically significant streptococci and their differentiation among β-hemolytic and group of Viridans streptococci using PYR, CAMP and optochine tests. 3) Neisseria, Corynebacteria and Listeria - Colony morphology using enriched and selective media, C. diphtheriae - toxigenity test. Temperature dependent culture of L. monocytogenes. 4) Enterobacteriaceae - Laboratory diagnosis of significant species and strains using biochemical tests and reverse agglutination method. 5) Bordetella, Haemophilus and Pseudomonas - Fastidious nature of Haemophilus species and special enriched media. Specimen collection and diagnostic media to detect Bordetella species. Colony pigmentation and resistance of Pseudomonas aeruginosa strains. 6) Anaerobic bacteria - Anaerobic culture conditions. Overview of clinical material collected from patients with suspected anaerobic infection. Identification of clinically significant anaerobic agents using biochemical tests. Spore-forming anaerobes of the Clostridium genus. 7) Mycobacteria and Candida - Ziehl-Neelsen stain of acid-alcohol resistant mycobacteria; culture of medically significant mycobacterial strains. Yeasts and moulds - native prepration and culture of medically significant species. 8) Interpretation of laboratory results - Overview of laboratory methods applicable in diverse clinical situations. Interpretation of microbiological and serological results. 9) Parasitology - Microscopy and macroscopy in identification of clinically significant parasites. Summary of general parasitology. 10) Molecular methods in clinical microbiology - Overview of molecular methods applicable in medical microbiology laboratory - benefit and limitation. 11) Specimen collection and transport of clinical material - Applicable methods to collect and transport clinically significant clinical specimens. Gram staining procedure. 12) Processing of respiratory and urogenital specimens to detect infectious agents. 13) Processing of gastrointestinal specimens - Diagnostics of bacterial (Salmonella, Shigella, Campylobacter) and other agents. Transmission of the agent and relevant therapeutical properties. Review - overview of relevant clinical material and diagnostic procedures. 14) Consultation, credit - Completed credit test and absolute presence is required to receive the credit. |