The Basics of Cancer Molecular Biology - B83588 (volitelný předmět)

• Anglický název: The Basics of Cancer Molecular Biology
• Zajišťuje: Onkologická klinika 1. LF UK a FTN (11-00451)
• Fakulta: 1. lékařská fakulta
• Platnost: od 2023
• Semestr: letní
• Body: 3
• E-Kredity: 3
• Způsob provedení zkoušky: letní s.:
• Rozsah, examinace: letní s.:12/0, Z [HS]
• Rozsah za akademický rok: 12 [hodiny]
• Počet míst: 15
• Minimální obsazenost: 3
• 4EU+: ne
• Virtuální mobilita / počet míst pro virtuální mobilitu: ne
• Stav předmětu: vyučován
• Jazyk výuky: angličtina
• Způsob výuky: prezenční
• Způsob výuky: prezenční
• Poznámka: předmět pro jiné fakulty; předmět je možno zapsat mimo plán; povolen pro zápis po webu
• Garant: MUDr. Ludmila Boublíková, Ph.D.
• Atributy: Lékařství; Klinický předmět

Anotace

Poslední úprava: Marcela Holanová (12.07.2023)

It is an interdisciplinary cross-curricular subject that summarizes the essential aspects of the molecular biology of malignant tumors and puts them in the context of their clinical behavior, course of the disease and response to treatment. Each topic covers basic biological facts and principles, their specific application in the development of oncological diseases, method of detection, possibilities of use in the diagnosis and treatment of tumors.

Sylabus

Poslední úprava: Marcela Holanová (12.07.2023)

1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells
2. Genetic predispositions, hereditary cancer syndromes
3. Cell signaling, growth factor receptor pathways
4. DNA damage and repair, epigenetic alterations
5. Cell cycle, ploidy, chromosomal aberrations
6. Apoptosis, cell immortalization
7. Cancer cell metabolism
8. Tumor radiobiology
9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs
10. Immune response, tumor microenvironment, microbiome
11. Methods in molecular biology, predictive testing, tumor molecular classification
12. Molecular-based therapy, gene therapy

Rozpis výuky

česky

Rozpis datumový
Den	Datum	Popis	Učitel	Soubory	Poznámka	Hodnocení
Středa	06.03.2024	14:00 - 15:30 1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells 2. Genetic predispositions, hereditary cancer syndromes Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Středa	13.03.2024	14:00 - 15:30 3. Cell signaling, growth factor receptor pathways 4. DNA damage and repair, epigenetic alterations Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Středa	20.03.2024	14:00 - 15:30 5. Cell cycle, ploidy, chromosomal aberrations 6. Apoptosis, cell immortalization Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Středa	27.03.2024	14:00 - 15:30 7. Cancer cell metabolism 8. Tumor radiobiology Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Středa	03.04.2024	14:00 - 15:30 9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs 10. Immune response, tumor microenvironment, microbiome Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Středa	10.04.2024	14:00 - 15:30 11. Methods in molecular biology, predictive testing, tumor molecular classification 12. Molecular-based therapy, gene therapy Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090

anglicky

Schedule by date
Day	Date	Description	Teacher	Files	Note	Hodnocení
Wednesday	06.03.2024	14:00 - 15:30 1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells 2. Genetic predispositions, hereditary cancer syndromes Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Wednesday	13.03.2024	14:00 - 15:30 3. Cell signaling, growth factor receptor pathways 4. DNA damage and repair, epigenetic alterations Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Wednesday	20.03.2024	14:00 - 15:30 5. Cell cycle, ploidy, chromosomal aberrations 6. Apoptosis, cell immortalization Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Wednesday	27.03.2024	14:00 - 15:30 7. Cancer cell metabolism 8. Tumor radiobiology Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Wednesday	03.04.2024	14:00 - 15:30 9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs 10. Immune response, tumor microenvironment, microbiome Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090				průměr: 5, hodnoceno: 1x
Wednesday	10.04.2024	14:00 - 15:30 11. Methods in molecular biology, predictive testing, tumor molecular classification 12. Molecular-based therapy, gene therapy Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090