Pharmacology is a dynamically developing field in which the knowledge of physiology, biochemistry and
molecular biology is closely intertwined. It is also a field reflecting the clinical aspects of the disease. Although the
number of authorized drugs increases every year, it is also necessary to be aware of the complicated path that a
potentially effective newly discovered drug substance must go before it can be evaluated in clinical trials and reach
the patient. Even then, however, her life cycle does not end. Even after its introduction into routine clinical practice,
its safety is constantly monitored and in the event of the discovery of another substance with a better efficacy-safety
profile, it is completely replaced. There are not many active substances that are commonly used for several
decades.
Cíl předmětu - angličtina
Poslední úprava: Jana Kolářová (11.02.2020)
Knowledge and skills to be acquired: prescription, knowledge of basic principles of general pharmacology - pharmacokinetics, pharmacodynamics. Knowledge of basic principles of special pharmacology - knowledge of group characteristics of drugs according to anatomical systems and their diseases, including clinical indications and side effects.
Sylabus - angličtina
Poslední úprava: Jana Kolářová (11.02.2020)
Lectures:
What is pharmacology?
The scope of Pharmacology: goals, developmentof new drugs.
Pharmacokinetics I - basic principles, absorption and distribution of drugs.
Prescriptions I - (Brand name drugs), AISLP (automated information system for pharmaceutical preparations).
Pharmacokinetics II - drug elimination and clinical significance. Pharmacodynamics I - mechanisms of drug action.
Pharmacodynamics II - quantitative aspects of drug action; receptor-ligand system. Side effects of drugs; principles of gene therapy.
Drugs affecting autonomic nervous system, general principles; Sympathomimetics; Sympatholytics.
Local anesthetics. Introduction to drugs acting on CNS.
General anesthetics, preanaesthetic medication. Psychopharmacology; classification of main groups; neuroleptics.
Antidepressants, antimanics, psychostimulants.Nootropic and cognitive drugs, possible pharmacological intervention in neurodegenerative diseases.
Pharmacology of pain; opioid analgesics. Nonsteroidal anti-inflammatory drugs.
Hypnotics and anxiolytics. Antiepileptics.
Nitric oxide, donors and inhibitors and clinical implications. Drugs used in angina pectoris.
Diuretics. Drugs used in heart failure.
Antiarrhytmics. Drugs acting on the coagulation, platelet adhesion and fibrinolysis. Drug used in anemias; hematopoietic growth factors.
Drugs used in GIT diseases. Drugs used for treatment respiratory diseases.
Hormones as drugs, an overview.
Seminars:
Basic principles of drug prescription. Demonstration of pharmaceutical formulations and applications.
Prescriptions II - compounded prescriptions prepared by the pharmacist ("magisterial prescriptions"). Possible guided tour to the teaching hospital pharmacy.
Clinical implications of pharmacokinetic analyses, computer simulations. Possible guided tour to the teaching hospital pharmacy.
Molecular mechanism of drug action - computer simulations, TEST on prescription writing.
Biotransformation of drugs - significance of enzyme induction and inhibition; computer simulations. Laboratory demonstration.
Metabolism of drugs - pharmacogenetics; computer simulations. TEST on pharmacokinetics. Laboratory demonstration.
Drug interactions, drug poisoning. Laboratory demonstration.
Antiparkinsonics; computer simulations. TEST on pharmacodynamics.
H1 and H2 antihistamines - therapeutic uses of autacoids.
Ethanol and other drugs of abuse; drug dependence, computer simulation. Student´s seminar on a given topic
Neuroleptics (pharmacotherapy of schizophrenia - computer simulation. Students´seminar on a given topic)
Pharmacology of bronchial asthma (Computer simulation). TEST on ANS.
Corticosteroids as drugs and adrenocortical antagonists.
Literatura
Poslední úprava: Jana Kolářová (11.02.2020)
Povinná:
B.G.Katzung (editor). Basic and Clinical Pharmacology. OH, United States: The McGraw Hill Companies, 2017, 1264 s. ISBN 10 1259641155.
R.A. Harvey, Clark M.A, R. Finkel, J.A. Ray, K.W. Whalen (eds.). Lippincott’s illustrated reviews: Pharmacology. Philadelphia, US: Lippincott Williams & Wilkins, 2018, 608 s. ISBN 10-1451113145.
H.P. Rang, M.M. Dale, J.M. Ritter (eds.). Pharmacology. London, UK: Churchill Livingstone, 8th edition, 2019, 776 s. ISBN 10-0702053627.
L.L. Brunton, K.L. Parker (eds.), D.K Blumenthal., I.L Buxton. Goodman & Gilman’s Manual of Pharmacology and Therapeutics. New York City: McGraw-Hill, 2014, 642 s. ISBN 10-0071443436.
Metody výuky
Poslední úprava: MUDr. Nikolina Kutinová Canová, Ph.D. (01.02.2024)
Dear Students,
pharmacology is taught according to syllabus (education plan) published in the SIS. Teachers are available to you by prior arrangement for possible personal consultations - for contacts see Kontakty - Farmakologický ústav (cuni.cz).
Organization of teaching of the master's form of study at the Institute of Pharmacology of the 1st Faculty of Medicine, Charles University, for the summer semester:
Lectures
- take place always on Wednesdays from 12.45 to 14.15 in the lecture hall of the Institute of Pharmacology (FARMP1, 2nd floor of the Purkinje Institute, Albertov 4), unless otherwise stated in the SIS (see Education plan).Due to the reconstruction of the auditorium, lectures will be held until further notice in the auditorium of the Institute of Hygiene and Epidemiology, HYGEP1 - Studničkova 7 (secretariat Mgr. Brücknerová, line 8534).
Seminars
- Attendance at seminars held in a full-time form remains mandatory.
- Passing the compulsory tests listed for the given subject in the syllabus (see Education plan).
- For the list of seminar rooms and group teachers see below
Credit - conditions for granting credit:
1. full-time completion of practical training (maximum 2 absences on seminars are allowed);
2. successful passing of 4 compulsory tests given by the subject syllabus (see "Education plan" in SIS).
If you have any questions, do not hesitate to contact us.
MUDr. Nikolina Kutinová Canová, Ph.D. (ncano@lf1.cuni.cz ), representative for teaching
prof. MUDr. Ondřej Slanař, Ph.D. (oslan@lf1.cuni.cz ), head of the department
A list of seminar rooms and group teachers for summer semester 2023/2024:
Poslední úprava: MUDr. Nikolina Kutinová Canová, Ph.D. (15.02.2023)
Pharmacology 1 is completed by credit.
Conditions for granting credit from pharmacology • active participation in seminars, maximum two absences • Successful completion of all tests according to the seminar program
Pharmacology final questions exam from 2020/2021
1. - Adrenergic mediation (adrenergic neurotransmission, types of receptors, their localization and function, classification of substances affecting sympathetic drugs - substances acting directly and indirectly). - Hypnotics, sedatives.
2. - Cholinergic mediation (cholinergic transmission, cholinergic receptors, their localization and influ-enced functions, main uses of particular groups of cholinergic substances). - Drugs affecting bone mineral homeostasis, osteoporosis treatment.
3. - Non-steroidal anti-inflammatory agents, mechanism of action, therapeutic use, adverse reactions (including adverse reactions of specific COX-2 inhibitors). - Combination of antimicrobial agents; advantages and disadvantages, examples of synergism and antagonism of individual combinations.
4. - General anesthetics and medicines used for premedication. - Drug distribution in the body (volume of distribution - importance for drug dosing); one or more compartment models; zero and first order in pharmacokinetics.
5. - Noninsulin antidiabetics. - Central muscle relaxants - mechanism of action, therapeutic and adverse effects.
6. - Pharmacokinetics; basic parameters and formulas for calculation of pharmacokinetic parameters, importance of individual parameters. - Anticoagulants, including NOAC (new oral anticoagulants).
7. - Diuretics (classification, mechanisms of action; therapeutic use of individual groups of diuretics). - Principles of pain management - analgesics
8. - Antiepileptic drugs (groups of antiepileptic drugs including newer drugs, mechanism of action, principles of antiepileptic drug administration, drug choice for different types of epilepsy). - Treatment of anaphylactic shock.
9. - Parkinson's disease, Alzheimer's dementia and other degenerative CNS diseases - current possi-bilities of pharmacotherapy. - Dose-response (dose types, dose-effect relationship, plasma level-effect, therapeutic range, therapeutic index).
10. - β sympatholytics (classification; cardiac and non-cardiac indications of administration, adverse reactions). - Special features of pharmacotherapy in pregnancy and lactation; teratogenic effects of drugs; medicines that can be used during pregnancy in severe conditions (hypertension, diabetes, bron-chial asthma, infectious diseases, epilepsy).
11. - Ionotropics and medicines used in acute heart failure. - Drugs used against herpes viruses, influenza viruses and infectious hepatitis (review).
13. - Antimanics and antidepressants (groups of antidepressants including SSRIs, SNRIs, etc.). - Thyroid drugs.
14. - Intoxication drugs; principles of patient care, antidotes. - Antiasthmatics
15. - Time course of drug levels in the body. Importance for substance dosing optimization. Therapeu-tic drug monitoring (examples).
- Macrolides and antibiotics related to macrolides.
16. - Therapeutic options to reduce the activity of the renin-angiotensin-aldosterone system; impor-tance for prognosis in cardiovascular diseases. - Androgens and antiandrogens - effects and therapeutic use.
18. - Medicines used in dermatology. - Side and adverse effects of drugs - classification (dose-dependent - specific examples). Impor-tance of pharmacovigilance.
19. - Drugs used in angina (group review, other indications, side effects, absolute contraindications). - Side effects of antibiotics (allergic reactions, toxic effects on the nervous system, locomotive organs, gastrointestinal, haematopoietic, cardiovascular, nephrotoxicity) - examples.
20. - Alpha and beta sympathomimetics (classification according to selectivity, therapeutic use, adver-se effects). - Drug delivery routes to the body (relationship of the mode of administration to the rate and du-ration of action of the drug, relationship to the pharmacokinetics of the substance); dosage forms.
21. - Second choise antihypertensive drugs. - Antifungals for general and local use.
22. - Drugs used to treat obesity and metabolic syndrome. - Alkylating agents in cancer chemotherapy; mechanism of cytotoxic effect, adverse effects and toxicity, therapeutic use.
23. - Importance of increased sympathetic activity in cardiovascular diseases - therapeutic possibilities of its reduction. - Opioid analgesics.
25. - Parasympathomimetics (indication of administration, side effects). - Antiemetics, antimigraines.
26. - Betalactam antibiotics (except cephalosporins). - Special features of pharmacotherapy and drug dosage in children and the elderly. Dose ad-justment depending on elimination organ function.
27. - Local anesthetics, overview of substances, intoxication with local anesthetics. - Intestinal anti-inflammatory and other drugs used in non-specific inflammatory bowel disease (including biological drugs).
28. - The mechanism of action of drugs at the molecular level; drug-specific target structures; drugs with receptor independent effects (examples). - Cephalosporins (differences between groups, clinical use).
29. - Therapeutic use of anticholinergic agents. - Female sex hormones, hormonal contraceptives in women, hormone replacement therapy.
30. - Biotransformation of drugs and its importance for the excretion of drugs from the body (types of biotransfor-mations, enzyme induction and inhibition). - Chemotherapy of malignant tumors; classification, resistance to cytotoxic agents; hormonal sub-stances in the treatment of malignant tumors, newly developed substances (biological drugs, kina-se inhibitors, immunotherapeutics, etc.).
31. - Pharmacotherapy of chronic heart failure. - Laxatives and constipantion.
33. - Coronary vasodilators and agents used in ischemic heart disease. - Tocolytics, uterotonics and uterine-inducing drugs (prostaglandins).
34. - Antiplatelet and fibrinolytics. Hemostatics, antifibrynollytics. - Anabolic steroids - therapeutic use and abuse in athletes.
35. - Alpha-adrenergic sympatholytics, direct vasodilators, venopharmaceuticals. - Antirheumatics, antiuratics.
36. - Calcium channel inhibitors. - Drug interactions: types of interactions, interactions with food (examples). Polypragmasia.
37. - Interindividual variability in patient sensitivity to drugs (causes). Pharmacogenetics (importance, practical use, examples). - Antiarrhythmics (classification, mechanism of action); preferentially used antiarrhythmic drugs (including new substances).
38. - Antihistamines (classification, therapeutic indications, side effects). - Antimetabolites, antibiotics and plant alkaloids in the treatment of cancer.
39. - Basic quantitative aspects of pharmacon-receptor interaction (affinity, in-trinsic activity); ago-nism, partial agonism, competitive and non-competitive antagonism (graphically plotted on dose / concentration curve). - Immunosuppressants, immunomodulants (clinical application of immu-nosuppressants, relation-ship betwe-en immunotherapy and tumor chemotherapy).
40. - Substances used to treat allergic reactions. - Tetracyclines and related antibiotics, glycopeptide antibiotics, lincosamides, nitroimidazoles, chemotherapeutic agents inhibiting folic acid pro-duction.
41. - Antihypertensive overview; position of beta blockers among antihypertensives, beta blockers with vasodilatory effect. - Hypothalamic and pituitary hormones and their inhibitors - overview, clinical use.
42. - Drugs used to treat gastroduodenal ulcer disease. - Antiviral agents; drugs used to treat patients with HIV / AIDS (mechanisms of action, clinical use, side effects).
43. - Drugs used in cardiology in acute conditions (acute heart failure, myocar-dial infarction, hyper-tensive crisis). - Substances used in erectile dysfunction.
44. - Antibiotics for special uses (antistaphylococcal, anaerobes, legionella, chlamydia and pseudomo-nads). - Antitussives and expectorants; decongestion.
45. - Aminoglycosides; mechanism of action, indications, side effects. - Anxiolytics.
47. - Basic pharmacokinetic parameters affecting steady-state drug levels - elimination constant, eli-mination half-life, drug clearance, renal and non-renal clearance. - Treatment of addictions; smoking and drug interactions.
48. - Psychostimulants (clinical use, drug dependence) and nootropic agents. - Fluoroquinolones, quinolones and medicines for the treatment of urinary infections.
49. - Hypolipidemics - Antiprotozoal agents. Clinically used anthelmintics.
50. Pancreatic hormones; insulin (mechanism of action, types of insulins and their use in the tre-atment of diabetes mellitus). - Bronchodilators, COPD pharmacotherapy (review).
Rules of pharmacology examinations at the Pharmacological Institute of the First Faculty of Medicine List of exam dates All exam dates will be announced on SIS at the latest by the end of the 5th week of the semester. The number of exam dates is fixed and finite.
Exam dates for the summer semester will be announced by the end of the 5th week at the latest. Login to summer semester: Pre-exam dates and regular exam dates (from the 7th week in the semester) summer holidays (from the 3rd week of the regular exam period SS) 2nd part of the exam period SS in September (after the end of holiday exam dates)
Rules for enrollment and check-out The start of recording of exam dates will be indicated in the SIS and will be different for different groups of dates: • pre- exam dates (from the 7th week in the semester) • regular examination period (from the 7th week in the semester) • first 2 weeks in SS for examinations (from the 3rd week of regular exam period) • summer holidays (from the 3rd week of the regular exam period SS) • 2nd part of the examination period in September (after the end of the holiday period)
A student can apply for only one exam date at a time. He / she can enroll for the next exam date after the "failed" classification or after logging off from the previous exam date (see below). The student can take the exam only if he / she is enrolled for the exam date in SIS and has fulfilled all the requisites for the exam. Enrollment for the exam is not conditioned by the granting of credit, but the examination is in ad-dition to the credit of the subject is limited by the completion of the subject, which is a (pre) requi-site. A student who does not have the requisites will be deleted from the exam before the exam, and he will receive an e-mail. The exam date is not lost. Enrollment for the dates will be possible within 24 hours before the exam. Check-out will be pos-sible up to 48 hours before the exam.
Failure to attend the exam and apology The student must apologize to the assistant Olga Bartošová (omato@lf1.cuni.cz, tel. 224 968 030, 224 964 133) in writing or electronically, explaining and substantiating the reason for the apology. The student will be informed about the acceptance of the excuse and will be removed from the original exam date and will be able to register for a new exam date. The head of the subject may request clarification of the apology or its reason if the apology is not sufficient.
Retesting the exam The student has the right to take the exam no more than three times; However, if the student do-es not exhaust these possibilities within the announced deadlines, this does not constitute a right to announce a special exam date. Further exam dates will not be announced.
Examination rules The extent of knowledge required for the exam is defined by exam questions, pharmacology text-book and content of lectures and seminars. It is assumed that the student will acquire some know-ledge by self-study and that he / she will be able to apply the knowledge he / she acquired during the study of other subjects. The exam consists of two parts - written and oral. For the 1st and 2nd correction exam the student does not have to meet the point limit of the test. It is not allowed to use Pharmindex Brever or other drug databases during the test.
1. Written part a. Test Includes questions from the winter and summer semester. Students must pass a test with a limit of at least 70% correctly answered questions. If they do not meet the limit they are classified "failed". Students do not have to meet the point limit of the test at the 1st and 2nd correction exam. Test results are taken into account in the final evaluation (failure to meet the point limit may result in a significant reduction in the final evaluation of the exam).
b. Recipe It consists of a written prescription of two products. Significant ignorance may be the reason for the failure of the whole exam.
2. Oral part It consists of 2 questions that are drawn. If the student is on the second correction exam (third exam) is examined by a committee of at least two examiners.
Rozpis výuky -
Rozpis semestrální
Výukový týden
Datum
Od - Do
Typ výuky
Téma
Učitel
Soubory
Poznámka
Hodnocení
1
19.02.2024
14:30 - 16:45
seminář
Organization of teaching pharmacology seminars, conditions for granting credit, etc. Dosage forms, application routes. Basics of prescribing medicines; electronic prescription. Recipe for mass-produced medicinal products.
21.02.2024
12:45 - 14:15
přednáška
Characteristics of the pharmacology. Development of new drug, clinical evaluation and registration of drugs.
prof. MUDr. Ondřej Slanař, Ph.D.
Lectures on Pharmacology 1 will take place on Wednesdays from 00:45 PM to 02:15 PM
Due to the reconstruction of the auditorium, lectures will be held until further notice in the auditorium of the Institute of Hygiene and Epidemiology, HYGEP1 - Studničkova 7 (secretariat Mgr. Brücknerová, line 8534).
22.02.2024
14:30 - 16:45
seminář
Organization of teaching pharmacology seminars, conditions for granting credit, etc. Dosage forms, application routes. Basics of prescribing medicines; electronic prescription. Recipe for mass-produced medicinal products.
Compulsory seminars are scheduled on Monday and Thursday from 2:30 PM to 4:45 PM *
2 absences are allowed
*The program of seminars is always determined by the teacher in connection with the dates of lectures and free days.
2
26.02.2024
14:30 - 16:45
seminář
Prescription of individually prepared medicinal products. Practicing recipes.
The lecture will be held in the auditorium of the Institute of Hygiene and Epidemiology, HYGEP1 - Studničkova 7 (secretariat Mgr. Brücknerová, line 8534).
29.02.2024
14:30 - 16:45
seminář
Prescription of individually prepared medicinal products. Practicing recipes.
3
04.03.2024
14:30 - 16:45
seminář
Pharmacotherapy of pain; opioid and non-opioid analgesics. Pharmacotherapy options for migraine headaches.
06.03.2024
12:45 - 14:15
přednáška
Pharmacodynamics - basic terms, types of receptors, receptor theory (agonism / antagonism), receptor diseases, molecular mechanism of drug action in organism, concentration / dose - effect relationship.
MUDr. Olga Bartošová, Ph.D.
Since March 6, 2024, lectures will be held, until further notice, in the Institute of Pharmacology, the seminar room No. 2, door number 2080, the 1st floor of the Purkinje institute, Albertov 4, Prague 2.
07.03.2024
14:30 - 16:45
seminář
.Pharmacotherapy of pain; opioid and non-opioid analgesics. Pharmacotherapy options for migraine headaches.
4
11.03.2024
14:30 - 16:45
seminář
TEST – recipe/prescription writing. Drug interactions (overview), database of drug interactions (examples), database of clinical trials.
13.03.2024
12:45 - 14:15
přednáška
Vegetative nervous system: drugs affecting the sympathetic.
PharmDr. Jan Hartinger, Ph.D.
14.03.2024
14:30 - 16:45
seminář
TEST – recipe/prescription writing. Drug interactions (overview), database of drug interactions (examples), database of clinical trials.
5
18.03.2024
14:30 - 16:45
seminář
Pharmacokinetics - repetition + examples of calculations.
20.03.2024
12:45 - 14:15
přednáška
Vegetative nervous system: drugs affecting the cholinergic nervous system.
PharmDr. Jan Hartinger, Ph.D.
21.03.2024
14:30 - 16:45
seminář
Pharmacokinetics - repetition + examples of calculations.
6
25.03.2024
14:30 - 16:45
seminář
Antihistamines, antiemetics, pharmacotherapy options for allergic conditions
Since April 3, 2024, lectures will be held, in the lecture hall of the Institute of Pharmacology, Albertov 4, 2nd floor, door number: 3067.
04.04.2024
14:30 - 16:45
seminář
TEST - pharmacokinetics and pharmacodynamics. Psychotropic drugs: sedatives, hypnotics, anxiolytics
8
08.04.2024
14:30 - 16:45
seminář
TEST - pharmacokinetics and pharmacodynamics. Psychotropic drugs: sedatives, hypnotics, anxiolytics
10.04.2024
12:45 - 14:15
přednáška
Antiparkinsonians, cognitives, nootropics; overview of the possibilities of pharmacotherapy of multiple sclerosis.
MUDr. Olga Bartošová, Ph.D.
11.04.2024
14:30 - 16:45
seminář
Antihistamines, antiemetics, pharmacotherapy options for allergic conditions
9
15.04.2024
14:30 - 16:45
seminář
Local anaesthetics. + Repetition of autonomic nerve system (ANS) - clinical use of substances affecting ANS.
17.04.2024
12:45 - 14:15
přednáška
Antiepileptics, myorelaxants.
MUDr. Pavel Ryšánek, Ph.D.
18.04.2024
14:30 - 16:45
seminář
Local anaesthetics. + Repetition of autonomic nerve system (ANS) - clinical use of substances affecting ANS.
10
22.04.2024
14:30 - 16:45
seminář
TEST - ANS. Evidence-based medicine, EBM, drug information sources, drug databases. Basic terms: placebo, pharmacovigilance, polypragmasia, rational pharmacotherapy, orphan drugs.
Due to the shut-off of water in the entire Albertova campus, the pharmacology lecture cannot be held face-to-face on April 24, 2024. Therefore, the lecture will be held online in real time on MS Teams from 12:45 p.m.
25.04.2024
14:30 - 16:45
seminář
TEST - ANS. Evidence-based medicine, EBM, drug information sources, drug databases. Basic terms: placebo, pharmacovigilance, polypragmasia, rational pharmacotherapy, orphan drugs.
11
29.04.2024
14:30 - 16:45
seminář
Drugs used in anaesthesiology. General anaesthetics. Premedication.
01.05.2024
12:45 - 14:15
nic
FREE DAY
02.05.2024
14:30 - 16:45
seminář
Drugs used in anaesthesiology. General anaesthetics. Premedication.
12
06.05.2024
14:30 - 16:45
seminář
Insulin and non-insulin antidiabetics.
08.05.2024
12:45 - 14:15
nic
FREE DAY
09.05.2024
14:30 - 16:45
seminář
Insulin and non-insulin antidiabetics.
13
13.05.2024
14:30 - 16:45
seminář
Hormonal contraception, hormone replacement therapy. Testosterone and anabolic steroids.
15.05.2024
12:45 - 14:15
přednáška
Antitumor pharmacotherapy II: targeted anticancer treatment, immunotherapy of cancer
PharmDr. Irena Štenglová Netíková, Ph.D.
16.05.2024
14:30 - 16:45
seminář
Hormonal contraception, hormone replacement therapy. Testosterone and anabolic steroids.
14
20.05.2024
14:30 - 16:45
seminář
Test - antidiabetics. Phytopharmaceuticals, homeopathy.
22.05.2024
12:45 - 14:15
přednáška
Side effects of medicines. Pharmacology of drug abuse.
MUDr. Pavel Ryšánek, Ph.D.
23.05.2024
14:30 - 16:45
seminář
Test - antidiabetics. Phytopharmaceuticals, homeopathy.
15
27.05.2024
14:30 - 16:45
seminář
Drugs used in dermatology. CREDIT (does not have to be listed in the credit book, it is enough only in SIS).
29.05.2024
12:45 - 14:15
přednáška
Pharmacogenetics, pharmacogenomics, personalized medicine
přednášející: Dr. BSc. Michal Barabas, M.Phil.
30.05.2024
14:30 - 16:45
seminář
Drugs used in dermatology. CREDIT (does not have to be listed in the credit book, it is enough only in SIS).
Schedule semestral
Educational week
Date
From - To
Education type
Theme
Teacher
Files
Note
Hodnocení
1
19.02.2024
14:30 - 16:45
seminar
Organization of teaching pharmacology seminars, conditions for granting credit, etc. Dosage forms, application routes. Basics of prescribing medicines; electronic prescription. Recipe for mass-produced medicinal products.
21.02.2024
12:45 - 14:15
lecture
Characteristics of the pharmacology. Development of new drug, clinical evaluation and registration of drugs.
prof. MUDr. Ondřej Slanař, Ph.D.
Lectures on Pharmacology 1 will take place on Wednesdays from 00:45 PM to 02:15 PM
Due to the reconstruction of the auditorium, lectures will be held until further notice in the auditorium of the Institute of Hygiene and Epidemiology, HYGEP1 - Studničkova 7 (secretariat Mgr. Brücknerová, line 8534).
22.02.2024
14:30 - 16:45
seminar
Organization of teaching pharmacology seminars, conditions for granting credit, etc. Dosage forms, application routes. Basics of prescribing medicines; electronic prescription. Recipe for mass-produced medicinal products.
Compulsory seminars are scheduled on Monday and Thursday from 2:30 PM to 4:45 PM *
2 absences are allowed
*The program of seminars is always determined by the teacher in connection with the dates of lectures and free days.
2
26.02.2024
14:30 - 16:45
seminar
Prescription of individually prepared medicinal products. Practicing recipes.
The lecture will be held in the auditorium of the Institute of Hygiene and Epidemiology, HYGEP1 - Studničkova 7 (secretariat Mgr. Brücknerová, line 8534).
29.02.2024
14:30 - 16:45
seminar
Prescription of individually prepared medicinal products. Practicing recipes.
3
04.03.2024
14:30 - 16:45
seminar
Pharmacotherapy of pain; opioid and non-opioid analgesics. Pharmacotherapy options for migraine headaches.
06.03.2024
12:45 - 14:15
lecture
Pharmacodynamics - basic terms, types of receptors, receptor theory (agonism / antagonism), receptor diseases, molecular mechanism of drug action in organism, concentration / dose - effect relationship.
MUDr. Olga Bartošová, Ph.D.
Since March 6, 2024, lectures will be held, until further notice, in the Institute of Pharmacology, the seminar room No. 2, door number 2080, the 1st floor of the Purkinje institute, Albertov 4, Prague 2.
07.03.2024
14:30 - 16:45
seminar
Pharmacotherapy of pain; opioid and non-opioid analgesics. Pharmacotherapy options for migraine headaches.
4
11.03.2024
14:30 - 16:45
seminar
TEST – recipe/prescription writing. Drug interactions (overview), database of drug interactions (examples), database of clinical trials.
13.03.2024
12:45 - 14:15
lecture
Vegetative nervous system: drugs affecting the sympathetic.
PharmDr. Jan Hartinger, Ph.D.
14.03.2024
14:30 - 16:45
seminar
TEST – recipe/prescription writing. Drug interactions (overview), database of drug interactions (examples), database of clinical trials.
5
18.03.2024
14:30 - 16:45
seminar
Pharmacokinetics - repetition + examples of calculations.
20.03.2024
12:45 - 14:15
lecture
Vegetative nervous system: drugs affecting the cholinergic nervous system.
PharmDr. Jan Hartinger, Ph.D.
21.03.2024
14:30 - 16:45
seminar
Pharmacokinetics - repetition + examples of calculations.
6
25.03.2024
14:30 - 16:45
seminar
Antihistamines, antiemetics, pharmacotherapy options for allergic conditions
Since April 3, 2024, lectures will be held, in the lecture hall of the Institute of Pharmacology, Albertov 4, 2nd floor, door number: 3067.
04.04.2024
14:30 - 16:45
seminar
TEST - pharmacokinetics and pharmacodynamics. Psychotropic drugs: sedatives, hypnotics, anxiolytics
8
08.04.2024
14:30 - 16:45
seminar
TEST - pharmacokinetics and pharmacodynamics. Psychotropic drugs: sedatives, hypnotics, anxiolytics
10.04.2024
12:45 - 14:15
lecture
Antiparkinsonians, cognitives, nootropics; overview of the possibilities of pharmacotherapy of multiple sclerosis.
MUDr. Olga Bartošová, Ph.D.
11.04.2024
14:30 - 16:45
seminar
Antihistamines, antiemetics, pharmacotherapy options for allergic conditions
9
15.04.2024
14:30 - 16:45
seminar
Local anaesthetics. + Repetition of autonomic nerve system (ANS) - clinical use of substances affecting ANS.
17.04.2024
12:45 - 14:15
lecture
Antiepileptics, myorelaxants.
MUDr. Pavel Ryšánek, Ph.D.
18.04.2024
14:30 - 16:45
seminar
Local anaesthetics. + Repetition of autonomic nerve system (ANS) - clinical use of substances affecting ANS.
10
22.04.2024
14:30 - 16:45
seminar
TEST - ANS. Evidence-based medicine, EBM, drug information sources, drug databases. Basic terms: placebo, pharmacovigilance, polypragmasia, rational pharmacotherapy, orphan drugs.
Due to the shut-off of water in the entire Albertova campus, the pharmacology lecture cannot be held face-to-face on April 24, 2024. Therefore, the lecture will be held online in real time on MS Teams from 12:45 p.m.
25.04.2024
14:30 - 16:45
seminar
TEST - ANS. Evidence-based medicine, EBM, drug information sources, drug databases. Basic terms: placebo, pharmacovigilance, polypragmasia, rational pharmacotherapy, orphan drugs.
11
29.04.2024
14:30 - 16:45
seminar
Drugs used in anaesthesiology. General anaesthetics. Premedication.
01.05.2024
12:45 - 14:15
nothing
FREE DAY
02.05.2024
14:30 - 16:45
seminar
Drugs used in anaesthesiology. General anaesthetics. Premedication.
12
06.05.2024
14:30 - 16:45
seminar
Insulin and non-insulin antidiabetics.
08.05.2024
12:45 - 14:15
nothing
FREE DAY
09.05.2024
14:30 - 16:45
seminar
Insulin and non-insulin antidiabetics.
13
13.05.2024
14:30 - 16:45
seminar
Hormonal contraception, hormone replacement therapy. Testosterone and anabolic steroids.
15.05.2024
12:45 - 14:15
lecture
Antitumor pharmacotherapy II: targeted anticancer treatment, immunotherapy of cancer
PharmDr. Irena Štenglová Netíková, Ph.D.
16.05.2024
14:30 - 16:45
seminar
Hormonal contraception, hormone replacement therapy. Testosterone and anabolic steroids.
14
20.05.2024
14:30 - 16:45
seminar
Test - antidiabetics. Phytopharmaceuticals, homeopathy.
22.05.2024
12:45 - 14:15
lecture
Side effects of medicines. Pharmacology of drug abuse.
MUDr. Pavel Ryšánek, Ph.D.
23.05.2024
14:30 - 16:45
seminar
Test - antidiabetics. Phytopharmaceuticals, homeopathy.
15
27.05.2024
14:30 - 16:45
seminar
Drugs used in dermatology. CREDIT (does not have to be listed in the credit book, it is enough only in SIS).
29.05.2024
12:45 - 14:15
lecture
Pharmacogenetics, pharmacogenomics, personalized medicine
přednášející: Dr. BSc. Michal Barabas, M.Phil.
30.05.2024
14:30 - 16:45
seminar
Drugs used in dermatology. CREDIT (does not have to be listed in the credit book, it is enough only in SIS).
