Transposable elements: from junk DNA toad to Prince Major Driver of biodiversity - MB120P177

• Anglický název: Transposable elements: from junk DNA toad to Prince Major Driver of biodiversity
• Zajišťuje: Katedra botaniky (31-120)
• Fakulta: Přírodovědecká fakulta
• Platnost: od 2023
• Semestr: zimní
• E-Kredity: 4
• Způsob provedení zkoušky: zimní s.:
• Rozsah, examinace: zimní s.:2/2, Z+Zk [HT]
• Počet míst: 20
• Minimální obsazenost: 5
• 4EU+: ne
• Virtuální mobilita / počet míst pro virtuální mobilitu: ne
• Stav předmětu: zrušen
• Jazyk výuky: angličtina
• Další informace: https://lab-allience.natur.cuni.cz/plantreproevo/teaching/transposons
• Poznámka: povolen pro zápis po webu
• Garant: doc. Clément Lafon Placette, Dr.
• Je neslučitelnost pro: MB120P186

Anotace

Poslední úprava: doc. Clément Lafon Placette, Dr. (02.09.2020)

This course will be held in English.
Transposable elements (TEs), since their discovery, have been considered either as useless pieces of DNA, as selfish
parasitic genes or as major elements driving biodiversity. The aim of this course is to bring a holistic knowledge of
TEs, from the molecular mechanisms underlying their function to their impact on populations and species in
eukaryotes. It will involve lectures gathering current research issues as well as practicals involving modern tools
used in current research.

Sylabus

Poslední úprava: doc. Clément Lafon Placette, Dr. (04.10.2022)

Preliminary schedule:

Block 1: molecular aspects and developmental roles of TEs

·       Week 1 (7/10). Lecture: Introduction [CLP].

·       Week 2 (14/10). Lecture: TE families, modes of actions and evolution [CLP].

·       Week 3 (21/10). Lecture: Epigenetic silencing of TEs by host genomes [LF].

·       Week 4 (28/10). Holiday.

·       Week 5 (4/11). Lecture: TEs and sexual reproduction [CLP].

·       Week 5 (11/11). Homework.

·       Week 6 (18/11). Knowledge consolidation. Presentations. Essay practice [CLP].

 

Block 2: evolutionary implications of TEs

·       Week 11 (26/11). Lecture: Natural selection and TEs [CLP].

·       Week 8 (2/12). Lecture: Stress impact on TE activity [CLP].

·       Week 9 (9/12). Lecture: Molecular domestication of TEs [RB].

·       Week 10 (16/12). Lecture: TEs and biodiversity [CLP].

·       Week 12 (13/01/2023). Knowledge consolidation. Presentations. Essay practice [CLP].

 

Block 3: hands on TEs! (practical classes)

One week in January. Teachers: VC, IS and CLP. Detailed program TBA.

·       Day 1. Profiling the epigenetics of TEs 1.

·       Day 2. Profiling the epigenetics of TEs 2.

·       Day 3. Profiling the epigenetics of TEs 3.

·       Day 4. Identify and annotate TEs in genomes with RepeatExplorer 1.

·       Day 5. Identify and annotate TEs in genomes with RepeatExplorer 2.