Microbiology I - FG10017
Anglický název: Microbiology I
Zajišťuje: Ústav klinické mikrobiologie (15-560)
Fakulta: Lékařská fakulta v Hradci Králové
Platnost: od 2025
Semestr: letní
Body: 0
E-Kredity: 3
Způsob provedení zkoušky: letní s.:
Rozsah, examinace: letní s.:15/36, Z [HS]
Počet míst: neomezen
Minimální obsazenost: neomezen
4EU+: ne
Virtuální mobilita / počet míst pro virtuální mobilitu: ne
Kompetence:  
Stav předmětu: nevyučován
Jazyk výuky: angličtina
Způsob výuky: prezenční
Úroveň:  
Garant: prof. MUDr. Pavel Boštík, Ph.D.
Neslučitelnost : FV10015
Prerekvizity : FG10003, FG10005
Záměnnost : FA0104038
Je neslučitelnost pro: FV10015, FGP017
Je prerekvizitou pro: FG50026, FG10024, FG10025, FG10026
Ve slož. prerekvizitě: FGP037, FGP038, FGP039, FGP040, FGP041, FGP042, FGP043, FGP044, FGP045, FGP046, FGP047, FGP048, FGP049, FGP050, FGP051, FGP052, FGP053, FG10036, FG10038, FG10039, FG10040, FG10041, FG10042, FG10043, FG10044, FG10045, FG10047, FG10048, FG10049, FG10075, FG10076, FG10077, FG10078, FG10079, FG10080, FG10083, FG10084, FG10090, FG10091, FG10097, FG10098, FV081, FV126, FV144
Termíny zkoušek   Rozvrh   
Anotace - angličtina
Bacteriology: Gram positive and G negative bacteria, basic characteristic, pathogenicity, therapy and prevention of bacterial infections. Antibiotics: mechanisms of action, resistance, susceptibility testing, rules of ATB therapy and rules on the use. Virology: RNA and DNA viruses, Prions, basic characteristics. The antiviral therapy, the prevention of viral diseases. Mycology: basic characteristics of pathogenic fungi, local and systemic infections, opportunistic infections, mycoses and antifungal therapy. Parasitology: Protozoa, worms, basic characteristics, cycles in nature, in animals and in human population, pathogenicity. Arthropods: causative agents of diseases and vectors. Therapy and prevention of parasitic infections. Basics of clinical microbiology. Nosocomial infections and diseases. Vaccines and principles of immunization. Laboratory methods in microbiology.
Poslední úprava: Dyntarová Eva (24.01.2024)
Literatura - angličtina

Compulsory literature

  1. W.A. Strohl, H. Rouse, B.D. Fischer Microbiology, Lippincott Williams a Wilkins, 2001,ISBN 0-397-51568-5
  2. W. Levinson, E. Jawetz Medical Microbiology and Immunology. 4th ed.,Appleton and Lange, Stamford, USA, 1996. ISBN 0-8385-6225-6 (and newer editions)

Recommend literature

  1. G. F. Brooks et al. Medical Microbiology. 3th ed., Lange, 2004. ISBN 0-07-141207-7
  2. C. A. Mims et.al. Medical Microbiology. Mosby, 1993. ISBN 0-397-44631-4 (and newer editions)
  3. Oto Melter et Rute Castelhano. The MicroBook Clinical Microbiology fo Medical Students.2019. ISBN 978-80-246-3781-3

 

Poslední úprava: Dyntarová Eva (24.01.2024)
Požadavky ke zkoušce - angličtina

REQUIREMENT FOR CREDIT (Summer TERM)

 1. All protocols from practical classes completed

2. Not more than 1 excused absence (1 practical class)

3. Credit test accomplished

4. In case of more than 1 absence – oral examination on the missed topic by the group eacher

CREDIT TEST

1. Presented on the next-to-last final practical class

2. Location: the seminar room at the Microbiology department.  Students are responsible for having access to Moodle, which is required for the test.

3. Contains 20 multiple choice questions, time to complete: 20 minutes

4. Correct answers necessary to pass ≥ 70%

5. In case of failure to pass - only 1 correction attempt (mandatory)

 CORRECTION CREDIT TEST

The correction test is obligatory for all students who failed the 1st attempt.

In case of failure of the correction test – oral examination of the student on an assigned topic is given (the topic will be sent by email or directly given by a group teacher).

 ORAL EXAMINATION due to the missed practical class

Theme: the topic missed during the practical class or an assigned theme

Short oral examination without preparation, the topic and results will be recorded in the student’s report card.

Poslední úprava: Dyntarová Eva (26.01.2024)
Sylabus

Lecturers

  • Prof. P. Boštík, MD, Ph.D.
  • Assoc. Prof. Vladimir Buchta, M.Sc., Ph.D.
  • Vlasta Štěpánová, M.D., Ph.D.
  • Kateřina Neradová, M.D., Ph.D.

No. Theme Lecturers Duration

  1. Introduction to Medical Microbiology, Bacteriology. Cell structure. Morphology.(Boštík, Prof., MD, Ph.D.)
  2. Virology, general virology - taxonomy of viruses, detection of viral infection. Special virology - DNA and RNA viruses. Antiviral agents. (Štěpánová, M.D., Ph.D.)
  3. Mycology. Taxonomy. Yeasts, molds, dimorphic fungi. Antifungal agents. (Buchta, Assoc. Prof., Ph. D.)
  4. Parasitology. General parasitology. Protozoa, helminthoses. Antiparasitic agents. (Boštík, Prof., MD, Ph.D.)
  5. Antibiotics - summary, mechanisms of action, mechanisms of resistance, examples of clinical usage. (Neradová, M.D., Ph.D.)

Practical courses & seminars

Lecturers

  • Vlasta Stepanova, M.D., Ph.D.- 7
  • Rudolf Kukla,MSc/Miroslav Fajfr, MD, Ph.D.. - 8

Practical courses

  1. Microbiology - workflow in microbiology lab.
    Students are introduced into safety rules in microbiological laboratory. Attention is paid to the issue of disinfection and sterilization. Hand hygiene.
  2. Basic principles of microbiological diagnostics. Direct tests Part 1 (microscopy). Gram staining, cultivation. Preanalytical phase. Collection, transport, and maintenance of biological materials.
  3. Basic principles of microbiological diagnostics. Direct tests Part 2 (cultivation, biochemistry).
    Cultivation, culture media, conditions of cultivation, MALDI-TOF MS.
  4. Antibiotic susceptibility testing. Disc diffusion method. Microdilution method. Minimal inhibition concentration, break-point, interpretation of test results. Detection of betalactamase.
  5. Staphylococcus. Description of genus, morphology, enzyme detection. Staphylococcal toxins, therapy.
  6. Streptococcus. Description of genus, morphology, hemolytic streptococci, viridans group, pneumococci. identification, therapy. Indication of the methods in clinical practice.
  7. Enterobacteriaceae. Description of genus, endotoxin, exotoxins. Main species of genus. Serotyping. Clinical diseases.
  8. Pseudomonas, non-fermentative rods (Burkholderia, Stenotrophomonas). Identification of non-fermentative rods, oxidase test, exotoxins (pigment). Oportunistic pathogens. Role of non-fermentative rods in hospital acquired infections.
  9. Basic principles of microbiological diagnostics. Microbiological methods in mycology and parasitology
  10. Molecular-biological methods. Microscopy, cultivation. Principle of PCR, the pros and cons.
  11. Bordetella, Neisseria, Haemophilus. Cultivation, morphology, satelitism. Capsulated pathogens. Credit test.
  12. Mycobacterium, Corynebacterium, Nocardia, Listeria. Acid-fast staining. Tuberculosis. Listeriosis. Credit.

Notes: Actual informations about microbiology lectures and practical classes you can find on MOODLE and the board on the first floor of the department of microbiology (the building No. 17, Faculty Hospital).

 

 

Poslední úprava: Dyntarová Eva (24.01.2024)