Physical background of biological processes. Interaction of physical fields and ionizing radiation with organism. Basic medical instruments.
Poslední úprava: Tejral Gracian, Mgr., Ph.D. (30.09.2021)
Podmínky zakončení předmětu - angličtina
Exam
Poslední úprava: Tejral Gracian, Mgr., Ph.D. (30.09.2021)
Literatura - angličtina
AMLER, Evžen. Chapters from biophysics. Prague: Institute of Biophysics, Charles University, 2nd Faculty of Medicine, 2006. ISBN 978-80-239-8173-5.
HRAZDIRA, Ivo, Vojtěch MORNSTEIN and Aleš BOUREK. Biophysical principles of medical technology. Brno: Masaryk University, Medical faculty, 2000. ISBN 978-80-210-2414-4.
VÍTEK, František. Lectures on medical biophysics. Prague: Karolinum, 2004. ISBN 978-80-246-0893-8.
ALBERTS, Bruce et al. Essential Cell Biology. Fifth edition. New York: W. W. Norton & Company, 2019. ISBN 978-0-393-68037-9.
general physics overview (e.g. YOUNG, Hugh D. and Roger A. FREEDMAN. University physics with modern physics. 15th edition. Hoboken, N.J.: Pearson Higher Education, 2020. ISBN 978-0-13-515955-2.)
Eye as an optical system - physical characteristics optical eye defects and correction
Eye as a light detector, biophysics of vision
Color of light, perception and sensitivity
Atom structure
Forms of ionizing radiation, their origin X-ray (RTG) radiation, origin, properties and applications
Characteristics of X-rays, possibility of their modification
Natural and artificial sources of ionizing radiation
Fundamental principles of interaction of radiation with the environment Interaction of electromagnetic radiation with matter
Biological effects of ionizing radiation, radionuclides in medicine
Thermodynamic system, state quantities; internal energy, heat, work
First and second law of thermodynamics Entropy in living organisms
Measurement of temperature, thermometry, thermography, general types of thermometers, medical thermometers
Thermal well-being of an organism, regulation of temperature in the organism, hyperthermia and cryotherapy
Biophysical principle of energy transformation in the mitochondrial membrane
Biophysical basis of ATP synthesis at the ATP synthase
Structure of biomembranes
Laser – principle, characteristics and properties of a beam Application of laser radiation, lasers in medicine
Cytometry (flow cytotometry, cell-sorting, FACS)
Endoscopy principle
Optical microscopes (microscope for transmitted and incident light, phase contrast, polarization microscope, fluorescence microscope)
Electron microscope
Fluorescence spectroscopy (steady-state spectroscopy, quenching of fluorescence, lifetimes of the excited state, fluorescence polarization, fluorophores)
Principle of imaging methods based on ionizing radiation (RTG, PET, SPECT, CT)
Principle of imaging methods based on non-ionizing radiation (sonography, thermography, MRI)
Biosignals
Electrical manifestation of organism and their subsystems
Electrodes; artefacts Native record, provocation and stimulation
Biosignal processing and analysis; channel
Differential amplifiers and integrations of inputs
