Subjects

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Biochemistry for IES - MO550P88

Title:	Biochemie pro ŽP
Czech title:	Biochemie pro ŽP
Guaranteed by:	Institute for Environmental Studies (31-550)
Faculty:	Faculty of Science
Actual:	from 2020
Semester:	winter
E-Credits:	4
Examination process:	winter s.:
Hours per week, examination:	winter s.:2/0, Ex [HT]
Capacity:	unlimited
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	Czech
Note:	enabled for web enrollment

Guarantor:	Mgr. Radek Indra, Ph.D.
Teacher(s):	Mgr. Radek Indra, Ph.D.

Opinion survey results Examination dates WS schedule

Annotation -

Last update: Mgr. Radek Indra, Ph.D. (24.10.2019)

The course is primarily for students of Environmental Protection and Social Epidemiology. The course covers the whole area of general biochemistry and basic metabolic processes. Emphasis is placed on understanding the interdependence of processes in cells with regard to human diseases and the environment.

Literature -

Last update: Mgr. Radek Indra, Ph.D. (24.10.2019)

Presentations from the lectures are sufficient materials for the exam. Further information

Textbooks

Sofrova et al.: Biochemistry Basic Course (UK, 2009) (in Czech)

M. Kodicek, O. Valentova, R. Hynek: Biochemistry: Chemical View of the Biological World (VSCHT, 2015) (in Czech)

D. Voet, J.G. Voet: Biochemistry (Wiley, 2011) (in English)/ Biochemistry (Victoria Publishing, 1996) (in Czech)

Requirements to the exam -

Last update: Mgr. Radek Indra, Ph.D. (04.10.2021)

The exam is oral, written or combined based on an agreement on the opening lecture in the extent of the subject matter. Questions are drawn from a list of questions provided to students during the semester.

Syllabus -

Last update: Mgr. Radek Indra, Ph.D. (24.10.2019)

1. Prokaryotic and eukaryotic cells - composition and importance of cellular components

2. Amino acids - classification and chemical properties. Peptides and proteins - peptide bond, classification, structure and function

3. Enzymes - classification, rate of enzyme reaction, enzyme inhibition, mechanism of enzyme catalysis

4. Monosaccharides - classification and physico-chemical properties. Disaccharides. Polysaccharides - structural and storage importance. Sugar derivatives

5. Nucleic acids - components of nucleic acids, importance of nucleotides

6. Lipids - fatty acids and other classes of lipids. Cell membrane - composition and importance

7. Membrane transport - passive and facilitated diffusion, active transport. transport-related diseases

8. Classification of organisms according to energy sources. Macroergic compounds. Photosynthesis - light and dark phase. Respiratory chain and ATP formation

9. Metabolism of simple carbohydrates - glycolysis, fermentation, pyruvate dehydrogenase complex, gluconeogenesis. Diabetes mellitus

10. Citrate and glyoxalate cycle. Pentosaphosphate pathway of carbohydrate metabolism. Metabolism of glycogen and starch

11. Metabolism of triglycerides, synthesis and degradation of fatty acids. Lipid cleavage as a source of water

12. Cell cycle, DNA replication and transcription. DNA damage and their repair