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Applied nuclear chemistry - MC240P59

Title:	Aplikovaná jaderná chemie
Czech title:	Aplikovaná jaderná chemie
Guaranteed by:	Department of Inorganic Chemistry (31-240)
Faculty:	Faculty of Science
Actual:	from 2019
Semester:	summer
E-Credits:	3
Examination process:	summer s.:oral
Hours per week, examination:	summer s.:2/0, Ex [HT]
Capacity:	unlimited
Min. number of students:	4
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	Czech
Note:	enabled for web enrollment

Guarantor:	RNDr. Václav Tyrpekl, Ph.D.
Teacher(s):	doc. RNDr. Vojtěch Kubíček, Ph.D. RNDr. Václav Tyrpekl, Ph.D.

Opinion survey results Examination dates SS schedule

Annotation -

Last update: doc. RNDr. Vojtěch Kubíček, Ph.D. (08.04.2013)

The course is aimed at the most important application of temporary nuclear chemistry.
The first part shows chemical aspects of nuclear energy sources – uranium mining and processing, types of
nuclear power plants, nuclear fuel processing, applied materials.
The second part brings overview of medical applications of nuclear chemistry in radiotherapy and imaging
techniques PET and SPECT – properties and production of important radionuclides, fundamental aspects of
medical application.

Literature -

Last update: doc. RNDr. Vojtěch Kubíček, Ph.D. (26.10.2019)

V. Majer: Základy jaderné chemie, Základy jaderné chemie. SNTL Praha 1981.
G. Choppin, J.-O. Liljenzin, J. Rydberg: Radiochemistry and Nuclear Chemistry, 3rd Edition, Butterworth - Heinemann, 2002
Comprehensive Nuclear Materials, 2012 Elsevier Ltd., Editor-in-Chief: Rudy J.M. Konings
K. Kupka, J. Kubinyi, M Šámal a kol.: Nukleární medicína, P3K Příbram 2007.

Requirements to the exam -

Last update: doc. RNDr. Vojtěch Kubíček, Ph.D. (07.02.2019)

Student has to write a manuscript dealing with the given topic and present overview of the topic. The presentations will be organised in the lecture time in the last three weeks of semestr. Additional questions will be asked in the frame of presentation to test knowledges.

Syllabus -

Last update: doc. RNDr. Vojtěch Kubíček, Ph.D. (23.11.2023)

Introduction, historical overview
Basic principles - nucleus, radioactivity, atom stability, nuclear fission, nuclear reactions
Radionuclide production - particle accelerators (ion sources, single-path accelerators, Van den Graaf, cyclotrons, synchrotrons, neutron sources), production yield, processing
Important radionuclides - medicine (¹³¹In,⁶⁷Ga, ^131,123I, ¹⁸F, ¹¹C, ¹⁵O), nuclear energy (^238,235U, ²³⁹Pu), nuclear fusion (H, D, T)
Introduction to nuclear energy - nuclear power plants (types), construction materials (concrete, steel, nuclear fuel, cooling water)
Nuclear fuel cycle - uranium mining and processing, uranium chemistry (salts, oxides), nuclear fuel, reprocessing
High-temperature chemistry (severe accidents) in nuclear power plants - phase diagrams (multicomponent) of nuclear materials, fuel degradation and reactor active-zone melting, leakage and chemistry of fission products.
Chemistry of radioactive elements - Uranium, Thorium, Radium, Radon, Polonium, Transuranium elements
Introduction to nuclear medicine, labeling of organic molecules for radiodiagnostics, radiopharmaceuticals - production, selectivity, biodistribution, targeting
Nuclear imaging techniques: Positron emission tomography (PET), Single photon emission computed tomography (SPECT), Radiotherapy - principles, most common isotopes, half-lives, ligand types