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Course, academic year 2023/2024
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Transposable elements: from junk DNA toad to Prince Major Driver of biodiversity - MB120P177
Title: Transposable elements: from junk DNA toad to Prince Major Driver of biodiversity
Guaranteed by: Department of Botany (31-120)
Faculty: Faculty of Science
Actual: from 2023
Semester: winter
E-Credits: 4
Examination process: winter s.:
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Capacity: 20
Min. number of students: 5
4EU+: no
Virtual mobility / capacity: no
State of the course: cancelled
Language: English
Additional information: https://lab-allience.natur.cuni.cz/plantreproevo/teaching/transposons
Note: enabled for web enrollment
Guarantor: doc. Clément Lafon Placette, Dr.
Is incompatible with: MB120P186
Opinion survey results   Examination dates   Schedule   
Annotation
Last update: doc. Clément Lafon Placette, Dr. (02.09.2020)
This course will be held in English.
Transposable elements (TEs), since their discovery, have been considered either as useless pieces of DNA, as selfish
parasitic genes or as major elements driving biodiversity. The aim of this course is to bring a holistic knowledge of
TEs, from the molecular mechanisms underlying their function to their impact on populations and species in
eukaryotes. It will involve lectures gathering current research issues as well as practicals involving modern tools
used in current research.
Syllabus
Last update: doc. Clément Lafon Placette, Dr. (04.10.2022)

Preliminary schedule:

Block 1: molecular aspects and developmental roles of TEs

·       Week 1 (7/10). Lecture: Introduction [CLP].

·       Week 2 (14/10). Lecture: TE families, modes of actions and evolution [CLP].

·       Week 3 (21/10). Lecture: Epigenetic silencing of TEs by host genomes [LF].

·       Week 4 (28/10). Holiday.

·       Week 5 (4/11). Lecture: TEs and sexual reproduction [CLP].

·       Week 5 (11/11). Homework.

·       Week 6 (18/11). Knowledge consolidation. Presentations. Essay practice [CLP].

 

Block 2: evolutionary implications of TEs

·       Week 11 (26/11). Lecture: Natural selection and TEs [CLP].

·       Week 8 (2/12). Lecture: Stress impact on TE activity [CLP].

·       Week 9 (9/12). Lecture: Molecular domestication of TEs [RB].

·       Week 10 (16/12). Lecture: TEs and biodiversity [CLP].

·       Week 12 (13/01/2023). Knowledge consolidation. Presentations. Essay practice [CLP].

 

Block 3: hands on TEs! (practical classes)

One week in January. Teachers: VC, IS and CLP. Detailed program TBA.

·       Day 1. Profiling the epigenetics of TEs 1.

·       Day 2. Profiling the epigenetics of TEs 2.

·       Day 3. Profiling the epigenetics of TEs 3.

·       Day 4. Identify and annotate TEs in genomes with RepeatExplorer 1.

·       Day 5. Identify and annotate TEs in genomes with RepeatExplorer 2.

 
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