Subjects

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Medical Mycology - MB120P170E

Title:	Medical Mycology
Czech title:	Lékařská mykologie
Guaranteed by:	Department of Botany (31-120)
Faculty:	Faculty of Science
Actual:	from 2023
Semester:	summer
E-Credits:	4
Examination process:	summer s.:oral
Hours per week, examination:	summer s.:2/1, C+Ex [HT]
Capacity:	25
Min. number of students:	5
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	cancelled
Language:	English
Note:	enabled for web enrollment

Guarantor:	MUDr. Mgr. Vít Hubka, Ph.D.

Opinion survey results Examination dates Schedule

Annotation -

Last update: MUDr. Mgr. Vít Hubka, Ph.D. (20.03.2019)

The aim of the course is to gain complex insight into various aspects of fungal infections, which are becoming increasingly important in both human and veterinary medicine. The emphasis is given to the pathogenesis of the
disease, ecology and biology of major pathogens. The subject also includes an overview of modern approaches in the diagnostics and antifungal therapy of mycoses. During the practical course, the students will be acquainted
with basic characteristics of clinically important fungi in culture and microscopy, histopathological picture, cultivation and isolation techniques, antifungal susceptibility testing methods, basic diagnostic tests and their
evaluation.

Literature -

Last update: MUDr. Mgr. Vít Hubka, Ph.D. (20.03.2019)

Sullivan DJ & Moran GP (2014) Human Pathogenic Fungi: Molecular Biology and Pathogenic Mechanisms. Caister Academic Press. ISBN: 978-1-908230-44-7

Seyedmousavi S, de Hoog GS, Guillot J & Verweij PE (2018) Emerging and epizootic fungal infections in animals. Springer International Publishing. ISBN 978-3-319-72091-3

De Hoog GS, Guarro J, Gené J & Figueras MJ (2014) Atlas of Clinical Fungi, 4rd edn, CBS-KNAW Fungal Biodiversity Centre, Utrecht

Merz WG & RJ Hay (2011) Topley & Wilson's Medical Mycology 10th edn. Wiley India Pvt Ltd. ISBN: 8126533331

Requirements to the exam -

Last update: MUDr. Mgr. Vít Hubka, Ph.D. (20.03.2019)

Requirements: at least 70% attendance at lectures, submission of protocols from the practicalcourse.

Oral examination form.

Syllabus -

Last update: MUDr. Mgr. Vít Hubka, Ph.D. (20.03.2019)

1) Fungal virulence factors, host side risk factors, infection mechanisms, survival in the host

2) Immunological aspects of fungal infections - infection of a healthy and immunocompromised host

3) Mycological diagnostic methods, collection and processing of clinical material, laboratory markers of mycoses, diagnostic criteria for confirmation of invasive fungal infections

4) Antifungals - chemical classification, mechanisms of action and resistance, antifungal susceptibility testing methods

5) Invasive mycoses caused by filamentous fungi (Aspergillus, Mucorales, Fusarium, etc.)

6) Yeast infections (Candida, Cryptococcus, aj.)

7) Keratinophilic fungi and superficial mycoses

8) Subcutaneous mycoses; mycoses due to fungus-like eukaryotic microorganisms

9) Pneumocystis; endemic mycoses (dimorphic fungi)

10) Veterinary mycology I - mycoses in invertebrates and cold-blooded vertebrates

11) Veterinary mycology II - mycoses in warm-blooded vertebrates