Subjects

Your browser does not support JavaScript, or its support is disabled. Some features may not be available.

Biotechnology - GAPS231

Title:	Biotechnology
Guaranteed by:	Department of Pharmacognosy and Pharmaceutical Botany (16-16230)
Faculty:	Faculty of Pharmacy in Hradec Králové
Actual:	from 2022
Semester:	summer
Points:	0
E-Credits:	3
Examination process:	summer s.:written
Hours per week, examination:	summer s.:28/14, C+Ex [HS]
Capacity:	unknown / unknown (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	taught
Language:	English
Teaching methods:	full-time
Teaching methods:	full-time
Level:
Is provided by:	GAF231
Explanation:	(F 3.r.)
Note:	deregister from the exam date if a requisite was not fulfilled course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	doc. PharmDr. Tomáš Siatka, CSc.

Examination dates SS schedule

Annotation -

Last update: doc. PharmDr. Tomáš Siatka, CSc. (18.09.2023)

A basic course in biotechnology. The subject describes and explains concepts and theoretical principles underlying the biotechnology-based development and manufacturing of biologically active natural products as well as the other biotechnological applications relevant to the human health. Special attention is paid to biopharmaceuticals (manufacturing and applications).

Course completion requirements -

Last update: doc. PharmDr. Tomáš Siatka, CSc. (18.09.2023)

A requirement for passing credit is fulfiment of the following conditions:

presence at all seminars and fulfilment of seminar papers

Literature -

Last update: doc. PharmDr. Tomáš Siatka, CSc. (01.10.2021)

Obligatory:

Kristiansen, Bjørn Ratledge, Colin, (eds.). Basic biotechnology. Cambridge, U.K. ; New York: Cambridge University Press, 2006, 666 s. ISBN 0-521-84031-7.

Syllabus -

Last update: doc. PharmDr. Tomáš Siatka, CSc. (18.09.2023)

Biotechnology.

Basic terms.
History of biotechnology.

Industrial biotechnology.

Biotechnological process.
Industrial microorganisms.
Fermentation equipment, mixing, aeration, sterilization.
Culture media.
Microbial growth and product formation.
Fermentation monitoring and control.
Downstream processing.

Recombinant technology.

Protoplast and cell fusion.
Recombinant DNA technology.
Protein engineering.
Production of recombinant proteins.

Enzyme technology.

Enzymes and cells as biocatalysts.
Immobilized biocatalysts.
Industrial biotransformations.

Plant biotechnology.

Plant tissue culture.
Transgenic plants.

Animal biotechnology.

Animal cell culture.
Hybridoma technology.
Transgenic animals.

Pharmaceuticals produced by means of biotechnological methods.

Small molecules and biopharmaceuticals.
Antibiotics.
Immunosuppressant.
Alkaloids.
Enzymes.
Enzyme inhibitors.
Cytokines.
Monoclonal antibodies.
Fusion proteins.
Vitamins.
Amino acids, dipeptides.
Organic acids.
Oligosaccharides and polysaccharides.
Living cells and organisms.
Vaccines.
Genes.

Teaching methods -

Last update: Ing. Lucie Navrátilová (26.06.2020)

Lectures and practical classes.

Requirements to the exam -

Last update: doc. PharmDr. Tomáš Siatka, CSc. (01.10.2021)

To pass credit.