Biology of Tumor Cells - FV111

• Title: Biology of Tumor Cells
• Guaranteed by: Department of Medical Biology and Genetics (15-120)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2022
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Hours per week, examination: summer s.:24/6, C [HT]
• Capacity: 20
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: prof. PharmDr. Emil Rudolf, Ph.D.
• Comes under: General medicine - ELECTIVE subjects
• Pre-requisite : {Malá skupina pro předmět FV111}
• Incompatibility : FG50033
• Interchangeability : FG50033
• Is incompatible with: FG50033
• Is interchangeable with: FG50033

Requirements to the exam

Last update: Marcela Laláková (10.02.2024)

Credit:

Credit will be given to the students with at least 80 % attendance in lectures, practical classes and seminars. Each student must actively participate in panel discussion.

Syllabus

Last update: Marcela Laláková (10.02.2024)

Lecturers:

• Prof. PharmDr. Emil Rudolf, Ph.D.

Lectures:

1. Tumor heterogeneity
2. Signaling pathways in tumor cells 
3. Stem cell concept in tumorigenesis 
4. Chemoresistance and metabolism in tumor cell  
5. Barriers of tumorigenesis in tumor cells
6. Invasion and metastasis 
7. New approaches to biological treatment of tumors
8. Step by step carcinogenesis in selected examples of human malignancies

 
Practical courses:

1. Expression of cellular markers in malignant cells  
2. Proliferation and cell cycle analysis of tumor cell populations; Credit

Literature

Last update: Marcela Laláková (10.02.2024)

Compulsory literature:

1. Internet - based on-line databases Medline and PubMed