SubjectsSubjects(version: 945)
Course, academic year 2023/2024
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Molecular Medicine (biological, clinical, ethical and legal aspects) - FD10069
Title: Molecular Medicine (biological, clinical, ethical and legal aspects)
Guaranteed by: Department of Medical Biology and Genetics (15-120)
Faculty: Faculty of Medicine in Hradec Králové
Actual: from 2018
Semester: winter
Points: 0
E-Credits: 1
Examination process: winter s.:
Hours per week, examination: winter s.:0/15, C [HS]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: doc. RNDr. Věra Králová, Ph.D.
Pre-requisite : {Dentistry 3rd year}
Incompatibility : FZ10065
Interchangeability : FA0209137, FZ10065
Is incompatible with: FZ10065
Is interchangeable with: FZ10065
In complex pre-requisite: FD10083
Is complex co-requisite for: FD10083
Annotation
Last update: Marcela Laláková (17.09.2023)
Genomics in medicine – human genome, methods of gene mapping, genomics, transcriptomics, proteomics, translation of genomic data into clinical practice. Gene therapy – theoretical concepts, current clinical applications. Non-coding RNAs – functions, emerging medical significance. Biological therapy of tumours. Epigenetic mechanisms in the control of gene expression.
Requirements to the exam
Last update: Marcela Laláková (17.09.2023)

REQUIREMENTS FOR CREDIT

For credit, student should have attendance in seminars and pass a credit test.

Syllabus
Last update: Marcela Laláková (15.09.2023)

Practical courses & seminars

Lecturers:

  • Doc.RNDr. Vera Kralova, Ph.D.
  • Prof. PharmDr. Emil Rudolf, Ph.D.
  • RNDr. Jana Nekvindová, Ph.D.

Seminars

1. 11.

Genomics and the search for genes responsible for diseases. Gene therapy. 

Králová

 

 

 

8. 11.

Genetic heterogeneity of tumors.

Rudolf

 

 

 

15. 11.

Clinical applications of molecular genetic methods. 

Nekvindová

 

 

 

22. 11. 

Practical class: Clinical applications of molecular genetic methods – molecular genetic laboratories of the Derpartment of Clinical Biochemistry and Diagnostics, University Hospital. 

Nekvindová

 

 

 

 

Literature
Last update: Marcela Laláková (15.09.2023)

Recommend literature

  1. J. Pongracz, M. Keen Medical Biotechnology, Elsevier, 2009, ISBN 978-0-08-045135-0
  2. Internet - based on-line databases Medline and PubMed
 
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