Subjects

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Molecular aspects of cellular signalling, its disorders and clinical impact - CVOL0038

Title:	Molecular aspects of cellular signalling, its disorders and clinical impact
Guaranteed by:	Department of Pneumology 3FM CU and UHB (12-PNEU)
Faculty:	Third Faculty of Medicine
Actual:	from 2016
Semester:	summer
Points:	3
E-Credits:	3
Examination process:	summer s.:
Hours per week, examination:	summer s.:0/15, C [HS]
Extent per academic year:	15 [hours]
Capacity:	unknown / unknown (20)
Min. number of students:	3
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	not taught
Language:	English
Teaching methods:	full-time
Teaching methods:	full-time
Level:

Guarantor:	MUDr. Ilona Tietzová, Ph.D., MBA

Examination dates Schedule

Annotation -

Last update: Tomáš Pajl (02.07.2013)

The aim of this one-semester course is to provide the students the basic overview of molecular aspects of cell signaling, its disorders and clinical implications.

Aim of the course -

Last update: Tomáš Pajl (02.07.2013)

The aim of the course is to provide the students the basic overview of molecular

mechanims of cell signaling, its disorders and clinical implications.

The students will get information on the different molecular signaling pathways,

the mechamisms of their regulation and on their role in physiology and

etiopathogenesis of diseases.

Literature -

Last update: Tomáš Pajl (02.07.2013)

1. Voet D. and Voet J.G. Biochemistry, 3rd Edition. Wiley, New Jersey, 2004.

2. Runge M.S. and Patterson C. Principles of Molecular Medicine. 2.nd Edition.

Humana Press, New Jersey, 2006.

Teaching methods -

Last update: Tomáš Pajl (02.07.2013)

Lectures and seminars.

Syllabus -

Last update: Tomáš Pajl (02.07.2013)

Characterization of signal molecules, signaling pathways and molecular responses

to the signal. Hormone signaling. Cytokine signaling. Signaling aspects of

cholesterol biosynthesis regulation. Adhesion receptors signaling. Apoptotic

signaling.

Entry requirements -

Last update: Tomáš Pajl (02.07.2013)

12 hours in semesters