Genetics of susceptibility to infectious diseases - CPVL105

• Title: Genetics of susceptibility to infectious diseases
• Guaranteed by: Department of Medical Genetics 3FM CU (12-GEN)
• Faculty: Third Faculty of Medicine
• Actual: from 2023
• Semester: winter
• Points: 1
• E-Credits: 1
• Examination process: winter s.:
• Hours per week, examination: winter s.:0/15, C [HS]
• Capacity: unknown / unknown (20)
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: doc. Marie Lipoldová, CSc.
• Comes under: AVSEOB-PVK-3 (ZÁPIS); AVSEOB-PVK-4 (ZÁPIS); AVSEOB1-PVK-3 (ZÁPIS)
• Pre-requisite : C1VL001

Annotation

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

For the students of the 2nd, 3rd and 4th. This course is offered each academic year.

Aim of the course

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

To provide students with an integrated view of the principal mechanisms of genetic susceptibility to infectious diseases, with an emphasis on new developments.

Course completion requirements

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

70% attendance, short answers to basic questions.

Literature

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

Goering R, Dockrell H, Zuckerman M, Chiodini PL. Mims' Medical Microbiology and Immunology, 7th Edition, Elsevier, 2024 (or 6^th Edition, Elsevier 2019)

Delves PJ, Martin SJ, Burton DR, Roitt IM: ROITT’s Essential Immunology, 13th edition, Wiley Blackwell, 2017

Turnpenny PD, Ellard S, Cleaver R. Emery's Elements of Medical Genetics and Genomics, 16th Edition, Elsevier 2022

Journals: Nature, Science, Nature Genetics, Nature Reviews Genetics, Nature Reviews Immunology, Nature Biotechnology…

Requirements to the exam

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

70% attendance, short answers to basic questions.

Syllabus

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

• Overview of basic terms in description of infectious diseases

• Overview of basic terms and methods in genetics of susceptibility to diseases

• Genes influencing susceptibility to SARS-CoV-2

• Genes influencing susceptibility to HIV

• Natural selection during the Black Death

• Genetic influence on susceptibility to bacterial sepsis

• Genetic influence on susceptibility to Mycobacterium leprae

• Genetic influence on susceptibility to tuberculosis

• Genes controlling susceptibility to malaria

Entry requirements

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

Basic knowledge in genetics and immunology of infectious diseases.

Course completion requirements

Last update: doc. Marie Lipoldová, CSc. (08.01.2024)

70% attendance, short answers to basic questions.