Subjects

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IIC - 2. Pain - CMCP0233 (Pathological Physiology, Pharmacology, Anaesthesiology and Resuscitation, Radiotherapy and Oncology, Neurology, Chemistry and Pathobiochemistry, Psychiatry, Psychology, Neurosurgery)

Title:	IIC - 2. Bolest
Guaranteed by:	Department of Physiology 3FM CU (12-UFYN)
Faculty:	Third Faculty of Medicine
Actual:	from 2016
Semester:	summer
Points:	2
E-Credits:	2
Examination process:	summer s.:
Hours per week, examination:	summer s.:0/30, other [HS]
Capacity:	unknown / unknown (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	not taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time
Level:

Guarantor:	doc. RNDr. Anna Yamamotová, CSc.
Classification:	Medicine > Clinical Disciplines
Attributes:	Modul IIC

Examination dates Schedule

Annotation -

Last update: doc. RNDr. Anna Yamamotová, CSc. (25.11.2008)

?Pain? is a problem oriented-course, part of the module Theoretical Bases of Clinical Medicine. The curse includes pathological physiology, pharmacology and explains the mechanisms of pain of different origin and their treatment.

Aim of the course -

Last update: doc. RNDr. Anna Yamamotová, CSc. (30.05.2008)

The course will cover the anatomical and functional basis of pain disorders. Presentation of the neurobiology of pain and analgesia, clinical pain conditions, basic and applied research methods in the study of pain, and the theory and practice of pain management.

Of special interest will be information describing clinical examination, evaluation, interpretation, and treatment of pain disorders.

Literature -

Last update: doc. RNDr. Anna Yamamotová, CSc. (25.11.2008)

Textbook of Pain. P. D. Wall and R. Melzack, Eds. Edinburgh: Churchill Livingston 1999, 4th edition.

Sarafino, E. P.: Health psychology. New York: Wiley and Sons 1994, 1998 (chapters 11, 12).

Katzung BG et al.: Basic and Clinical Pharmacology, A Lange medical book, 1998

Rang HP et al.: Pharmacology, Churchil Livingstone, 1997

Harvey RA et al.: Lippincott?s Illustrated Reviews Pharmacology, Lippincott-Raven, 1997

Marco Mumenthaler: Neurology. Georg Thieme Verlag, Stuttgart, 1990.

Anne G. Osborn: Diagnostic Neuroradiology. Mosby, St. Louis, Baltimore, Boston, 1994.

Teaching methods -

Last update: doc. RNDr. Anna Yamamotová, CSc. (30.05.2008)

The course will be conducted in lecture and seminars.

Requirements to the exam -

Last update: doc. RNDr. Anna Yamamotová, CSc. (25.11.2008)

Test from pharmacology, final credit test.

Syllabus -

Last update: doc. RNDr. Anna Yamamotová, CSc. (30.05.2008)

Pathophysiology and psychophysiology of pain

Terminology used in pain physiology

Peripheral mechanisms of pain

Central mechanisms of pain

Central pain inhibitory mechanism, its neuroanatomical substrates and neurotransmitter systems

Classification of opioid receptors and their distribution in CNS

Measurement of pain

Psychological approaches to pain

Pain as a psychological phenomenon

Psychological factors influencing the rise and course of pain and reactions to it

Indication and application of psychological (counselling and psychotherapeutic) approaches in pain control

Aspects of pain in children

Pathophysiological and psychological aspects of pain in children

Pain measurement in children in regard of the age

Contact with the child with acute and chronic pain: as a source of information

Non-pharmacological approach to the pain in children

Pharmacology of pain

Opioid analgesics

Nonopioid analgesics

Determining of exemplary case studies

Schedule of pharmacotherapeutical design (problem, selection of drug group, concrete drug, drug form, doses, risks, individualization, economical aspects, further control)

Individual elaboration of appropriate case studies

Surgery of pain

Spinothalamic chordotomy - transsection of tractus spinothalamicus lateralis

comissurotomy ? transsection of comissura anterior (mediolongitudinal myelotomy)

central myelothermocoagulation ? thermal lesion at C1 or Th12 level

thermocoagulation in dorsal root entry zone ? exclusion of the secondary pain pathway neuron in the dorsal roots of spinal cord

electrostimulation methods

stereotaxic methods in thalamic region

intrathecal opiate application ? application of opiates into liquor spaces using permanent reservoirs

Anaesthesiological care and postsurgical pain

Anaesthesiological methods in pain therapy

Postoperative pain

Chronic and malignant pain

Obstetric analgesia

Therapy of pain in neurology

Acute and chronic pain

Headache

Primary headache: (migraine, tension type headache and related syndromes, cluster headache and related syndromes)

Secondary headache due to another cranial or extracranial disease.

Pains of Vertebral Column (vertebrogenic (spondylogenic) pain, radicular (neurogenic) pain

Pain control in cancer patients

Various types of pain in cancer patient ? somatic, visceral

Pain characteristics (acute and chronic pain)

The difference in pain control in cancer patient in comparison with non-cancer patient

Surgical therapy of pain (types of surgery)

Radiation therapy of pain (analgesic radiotherapy using external beam radiotherapy, ?half body irradiation?, brachytherapy using radioactive strontium in therapy of multiple bone involvement

Painkillers used in cancer patients

Psychotherapy as a part of complex care of cancer patient in pain

General rules for pain control in cancer patient

Psychiatric approach to pain

Psychiatric aspects of pain:

Psychogenic pain - somatoform pain disorder (ICD 10 category-F45.4)

Pain and pain treatment in the cognitive behavioural therapy

Psychopharmacology of pain

Case story clinical presentation