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Course, academic year 2023/2024
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Basic of Medical Chemistry and Biochemistry - CDHLC1
Title: Základy lékařské chemie a biochemie
Guaranteed by: Department of Hygiene 3FM CU (12-HYG)
Faculty: Third Faculty of Medicine
Actual: from 2019
Semester: winter
Points: 2
E-Credits: 2
Examination process: winter s.:
summer s.:
Hours per week, examination: winter s.:20/0, C [HS]
summer s.:0/20, C+Ex [HS]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: RNDr. Martin Jaček, Ph.D.
RNDr. Jana Fauknerová Matějčková, Ph.D.
Examination dates   Schedule   
Annotation -
Last update: RNDr. Pavla Balínová (27.10.2008)
Lectures are focused on basic knowledge of chemical bonds, chemical reactions, properties of solutions and analysis of biological material. The teaching also includes the basic overview of natural products and their characterictics. In summer semester lessons are continue on function of an eucaryotic cell. Function and diagnostic importance of enzymes are also explained. These concepts are followed by a summary of digestion and metabolism of basic nutrients. Principles of hormonal regulations and an effect of nutrition are included.
Aim of the course -
Last update: RNDr. Pavla Balínová (27.10.2008)

The primary aim is to inform students about some general rules in chemistry and an application of chemistry in medical practice. Students should be oriented in nomenclature of inorganic and organic compounds and they should be able to calculate basic chemical problems (concentration and pH of solutions). The second aim is to give an overview describing the structure, properties and importance of natural products (nucleic acids, saccharides, lipids, amino acids and proteins).

Then students are informed about structure and function of the cell, proteosynthesis and importance of enzymes. Lectures are focused on an integration of chemical and physiological knowledge of human body (e. g. digestion and metabolism of carbohydrates). Students should be able to understand the biochemistry of a muscle cell with the inclusion of muscle cell contraction. Hormonal regulations and basics of clinical biochemistry are also explained.

Literature -
Last update: MATEJ7A3 (27.09.2010)

Vacík J.: Přehled středoškolské chemie, SPN Praha 1999

Urban J.: Lékařská chemie (skripta 3. LF UK), Praha 1995

Němečková A. a kol.: Lékařská chemie a biochemie, Avicenum Praha 1991

Štern P. a kol.: Obecná a klinická biochemie pro bakalářské obory studia, Karolinum Praha 2005

Vodrážka Z.: Biochemie, Academia Praha 1999

Ledvina M. a kol.: Biochemie pro studující medicíny, Karolinum Praha 2005

Musil J., Nováková O.: Biochemie v obrazech a schématech, Avicenum Praha 1989

Teaching methods -
Last update: MATEJ7A3 (27.09.2010)

Lectures, 2 seminars

Requirements to the exam -
Last update: MATEJ7A3 (27.09.2010)

Credit test

Syllabus -
Last update: RNDr. Pavla Balínová (27.10.2008)

Winter semester:

Chemistry and medicine

Basics of laboratory medicine

Important organic analytes in body fluids

Important organic compounds in biochemistry

Structure, chemical and biological properties of saccharides

Structure, chemical and biological properties of lipids

Structure, chemical and biological properties of amino acids, peptides and proteins

Summer semester:

Introduction to biochemistry. Enzymes. Gain of an energy in the cell

Carbohydrate metabolism. Glycemia. Diabetes mellitus

Lipid metabolism. Lipoproteins. Ketone bodies.

Metabolism of amino acids and proteins. Ammonia detoxication.

Principle of muscle contraction. Energy metabolism of muscle cell.

Hormonal regulation of metabolic processes

Basics of clinical biochemistry

Entry requirements -
Last update: RNDr. Pavla Balínová (27.10.2008)

Succesfull passing the entrance examination (biology, chemistry)

 
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