SubjectsSubjects(version: 945)
Course, academic year 2023/2024
   Login via CAS
--:--
 
 Search ... Teachers Departments Classes Classification View by plans Setup
 
 
 
 Details
 
 
 
 
Regulation of transcription and tumorous transformation of cells - CCOC5809
Title: Regulace transkripce a nádorová transformace buňky
Guaranteed by: Department of Pneumology 3FM CU and UHB (12-PNEU)
Faculty: Third Faculty of Medicine
Actual: from 2016
Semester: winter
Points: 1
E-Credits: 1
Examination process: winter s.:
Hours per week, examination: winter s.:0/15, C [HS]
Extent per academic year: 15 [hours]
Capacity: unknown / unknown (8)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: not taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
Additional information: http://pozn. vyučuje dr. Vachtenheim
Note: course can be enrolled in outside the study plan
Guarantor: doc. MUDr. Jiří Vachtenheim, CSc.
Classification: Medicine > Clinical Disciplines
Examination dates   Schedule   
Annotation -
Last update: RADOVA (08.09.2008)
Basic course providing the students with principles of transcription of DNA and the molecular mechanisms which play a role in the malignant transformation of the cell.
Aim of the course -
Last update: RADOVA (08.09.2008)

The aim of the course is to present basic information in the field of transcription DNA as the first step in the expression of genetic information, and mechanisms that regulate transcription. Another aim is to summarize molecular changes linked to the malignant transformation of the cell and the role of transcription in this process.
Literature -
Last update: RADOVA (08.09.2008)

Alberts B. a kol., " Základy buněčné biologie", Espero Publishing, Ústí nad Labem, 1998.

Alberts B. et al.:"Molecular Biology of the Cell", 4th ed., Garland Science, N.Y. 2002.

Teaching methods -
Last update: RADOVA (08.09.2008)

Seminar and practical demostrations.
Requirements to the exam -
Last update: Pavlína Svobodová (22.09.2010)

Attendance 90%, passing the written test with 60% of correct answers.
Syllabus -
Last update: RADOVA (08.09.2008)

1. Regulation of transcription in eukaryotic cells

2. Oncoproteins of DNA viruses and tumor suppressor genes.

3. Defects in cell cycle regulation and apoptosis during malignant transformation

4. Transformation and immortalization of cells in the cell culture

5. Practical demonstration of cell cultivation and gene transfer into cultured cells

6. Clinical aspects of gene mutations in oncology

 
Charles University | Information system of Charles University | http://www.cuni.cz/UKEN-329.html