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Physiology - B83113 (Dentistry)
Title: Physiology
Guaranteed by: Institute of Physiology First Faculty of Medicine Charles University (11-00150)
Faculty: First Faculty of Medicine
Actual: from 2023
Semester: winter
Points: 10
E-Credits: 10
Examination process: winter s.:
summer s.:
Hours per week, examination: winter s.:5/1, C [HT]
summer s.:6/1, C+Ex [HT]
Extent per academic year: 195 [hours]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Explanation: prof. MUDr. O. Kittnar, CSc. MBA
Additional information: http://fyziologie.lf1.cuni.cz/medici-a-zubni-lekarstvi
Note: prefer medical statement
enabled for web enrollment
Guarantor: prof. MUDr. Otomar Kittnar, CSc., MBA
Comes under: Compulsory for Dentistry 2.y._23/24
Attributes: Předmět pro elearning
Teoretický předmět
Zubní lékařství
Pre-requisite : {splněna jedna z anatomií}, B81129, B81133, B83031
Interchangeability : B81404
Is pre-requisite for: B81164, B81156, B81155, B81159, B83151, B81157, B83156, B83145, B83149, B83148, B83153, B83155
In complex pre-requisite: B80079
Annotation
Last update: Jana Kolářová (16.09.2019)
The Physiology subject is read in winter and summer semesters. There are 38 lectures in winter semester and 45 lectures in summer semester. The lectures in the winter semester include physiology of the cell, general neurophysiology including physiology of muscles, blood, circulatory, respiratory and digestive systems. In the summer semester, regulation in which kidneys, the endocrine system and central nervous system take part are dealt with. Practical labs is aimed at verification of theoretical knowledge and at training certain skills through investigation of some functions of the human organism and their regulatory mechanisms as well as through experiments on animals. Computer models and patient simulators complement the labs. There are 8 lab sessions in one semester, each one lasting 2 teaching hours (16 teaching hours in each semester). The conditions for gaining the credits in either semester include active work in particular practical and a successful outcome of the revision tests.
Syllabus
Last update: Jana Kolářová (19.09.2019)
Lectures in Physiology - Winter semestr (DENTISTRY)

Medical Physiology, History of the Subject

Cellular Physiology, Cell Organelles

Cell Membranes

Membrane Transport

Ion Channels, Membrane Potentials and their Propagation

Signal Transduction

Receptors and Information Molecules

Cytoskeleton, Cell Junctions, Extracellular Matrix

Cell Cycle, Tussie Maintenance

Principles of Homeostasis, Blood, Plasma

Blood Cells, Hemopoiesis

Hemostasis and Blood Coagulation

Body Defence System

Respiration. Pulmonary Ventilation

Diffusion, Perfusion, Pulmonary Circulation

Gas Transport and Exchange

Regulation of Respiration, Respiration in Hypobaric and Hyperbaric Conditions

Circulation, Heart, Electrical Activity in the Heart

Cardiac Mechanics

Electrocardiogram

Events of the Cardiac Cycle

Arterial System

Microcirculation and Exchange, Veins and Venous Return

Cardiovascular Control

Special Circulations

Principles of Biological Regulation

Physiology of the Digestive System, Motility

Secretory Functions

Digestion, Absorption

Metabolism, Minerals and Vitamins

Splanchnic Circulation, Functions of the Liver

Regulation of Food Intake

Function of the Skin

Temperature Regulation

Summer semestr

Kidney and Body Fluids, Fundamentals of Renal Physiology, Glomerular Filtration

Epithelial Transport, Filtrate Processing in the Tubules, Clearance

Mechanisms for Controlling Extracellular Fluid Osmolality

Excretion and Regulation of the Sodium, Potassium, and Urea, Micturition

Body Acid-Base State and Its Regulation

Endocrinology, The Cellular Biology of Endocrine System

Neurohypophyseal Hormones, Neuropeptides, Growth Factors

Control of the Calcium and Phosphate Balance

Adrenocortical and Thyroideal Hormones

Adrenal Medulla, Endocrine Rhythms

Pancreas and Regulation of Carbohydrate Metabolism, Adipocytal hormones

Reproductive and Hormonal Functions of the Male, Sexual Differentiation

Reproductive and Hormonal Functions of the Female

Anterior Pituitary

Pregnancy and Lactation

Fetal and Neonatal Physiology

General Prionciples of Neuronal Functions

Synaptic Transmission, Neurotransmitters

Membrane Potentials, Role of Dendrites, Integrative Function of Neuronal Circuits

Sensory Processes

Somatic Sensations, Pain

Auditory System

Gustation and Olfaction

Visual System

Sensory Processing

Control of Movements, The Spinal Motor Control, Reflex Arc

Striated muscle

Control of the Posture, Eye Position, Locomotion, Chewing

Voluntary Movements, Motor Functions of Cerebral Cortex

Motor Functions of Cerebellum and Basal Ganglia

Autonomic Nervous System

Hypothalamus, Smooth muscle

Limbic system, Reward system

Integrative Functions of the Central Nervous System

Integrative Functions of Cerebral Cortex in Humans

Learning and Memory

Association Functions of the Cerebral Cortex

Development of neuronal circuits, Neuroplasticity

Milleu of the CNS, Blood Brain Barrier

Body Rhythms

Waking and Sleeping

Optimality in Physiological Mechanisms

Literature - Czech
Last update: MUDr. Kateřina Jandová, Ph.D. (13.09.2019)

Textbook of Medical Physiology, Edited by Arthur C. Guyton

W.B. Saunders Company, 8th edition or later

Medical Physiology: Principles for Clinical Medicine, Rodney A. Rhoades, David R. Bell

Principles of Physiology, Edited by Robert M. Berne and Matthew N. Levy

Review of Medical Physiology, William F. Ganong

Czech: Lékařská fyziologie - Otomar Kittnar a kolektiv (Grada 2011)
Teaching methods - Czech
Last update: doc. MUDr. Vladimír Riljak, Ph.D. (13.02.2024)

Physiology Labs Syllabus - Summer semestr 2023/2024 (B83113 - DENTISTRY)

Physiology labs are scheduled (every other week) for Thursday 14:15-15:45, Lecture Hall - Department of Physiology

WEEK

Program

Thursday date 

1

 Introduction to summer semester, vital systems revision, how to study Physiology, concept of physiological thinking

22.2.2024

3

Polyuria, Renal system, Water homeostasis

7.3.2024

5

Importance of glycaemia, oral glucose tolerance test, regulation of metabolism by endocrine system, using spectrophotometry in biomedicine

21.3.2024

7

 Body fluids, blood, plasma, hemostasis, Quick test, APTT test

4.4.2024

9

Metabolism measurement, basal vs. maximal metabolic turnover, relationship between breathing, cardiovascular system and metabolic turnover

18.4.2024

11

Physiology od senses

2.5.2024

13

 Reflex evaluation, consciousness, behavior valuation and testing, classification of behavior in physiology

16.5.2024

15

Revision test, Revision discussion, consultations and credit

30.5.2024

To obtain the credit the active participation in seminaries is compulsory plus test on the end of the semester has to be passed successfully.

Any hesitations please consult with Vladimír Riljak (via email or via MS Teams chat).

Labs are taking place in lecture hall - please use the entrance from behind of the building (street Studničkova)
Requirements to the exam - Czech
Last update: MUDr. Kateřina Jandová, Ph.D. (31.01.2023)

The final exam consist of three parts:

1. Written test (entrance test), questions are multiple choice, single correct ones.

2. Lab examination. One question from the lab practicals.

3. Theory examination. Three questions (triplet), one of them is neurophysiology.

 

Evaluation of exam:

The final exam takes part during the summer semester exam period. Exam is successfully passed upon successful passing of all three parts of exam. Third attempt is always oral indenpendently on the results of previous parts of the exam.

Each exam term consists of all three parts.

 

Examination requires:

1. Valid SIS exam registration for particular term, detailed dates for examination terms in summer semester will be announced on SIS and on our webpage

2. Physiology credits signed for winter and summer semesters

3. Student ID card

 

Excuse from the exam:

Students are obliged to claim the exam excuse ahead of the particular exam term, otherwise you exam term is spent (lost). Receiving your apology after the respective exam term requires reasonable and documented justification in order to not lose the term.

 

Topics for the Final Exam in Physiology

Exam questions for Dentists:

The cell
The cell (cell membrane, nucleus, organelles, function) 
Transport across cell membranes 
Ionic currents underlying membrane potentials 
Contraction in skeletal muscle 
Sensory transduction 
Tissue maintenance 
Body fluids
Homeostasis 
The blood 
The blood cells 
Hemostasis 
Blood groups 
Mechanisms of immunity 
Blood circulation
Electrical activity of the heart 
The normal electrocardiogram 
Events of the cardiac cycle 
Function of cardiac valves, heart sounds 
Cardiac output, regulation 
Blood pressure in the heart, arteries, capillaries and veins 
Exchange of materials in capillaries 
Control of the cardiac output 
Control of the blood pressure 
Control of the blood volume 
Control of the regional blood flow 
Fetal and neonatal circulation 
The coronary circulation 
The circulation of the lungs 
Cerebral circulation 
Splanchnic circulation 
The Respiratory System
Ventilation 
Diffusion and transport of respiratory gases 
Transport of oxygen in blood 
Transport of carbon dioxide in blood 
Control of respiration 
pH regulation in body fluids 
The Digestive System
Motility of the gastrointestinal system 
Chewing and swallowing 
Secretion in the gastrointestinal system 
Digestion 
Absorption in the gastrointestinal system 
Functions of the liver 
Metabolism of nutrients 
Temperature regulation 
The excretory system
The physiology of the skin 
Glomerular filtration, its regulation 
Processing of the filtrate in the proximal and distal tubules 
Control of extracellular fluid osmolality 
Control of extracellular fluid volume, sodium and potassium balance 
Body acid-base state and its regulation 
Renal regulation of the acid-base balance 
Micturition 
The endocrine system
Mechanisms of cell signaling 
The adrenocortical hormones 
Growth hormone, growth factors, and control of the body growth 
Regulation of the carbohydrate metabolism 
Hypothalamo-hypophyseal relations 
The thyroid hormones secretion and its regulation 
The adrenal medulla 
Stress and emergency reaction 
Control of the calcium and phosphate balance 
Hormones of the anterior pituitary 
Neurohypophyseal hormones 
Endocrine and biological rhythms 
Reproductive and hormonal functions of the male 
Reproductive and hormonal functions of the female 
The ovarial cycle 
Physiology of pregnancy 
Fetal and neonatal physiology 
Principles of neurophysiology
Structure and function of nerve cells 
Membrane potentials 
Synaptic transmission 
Integration activity of neurons 
Reflex arc, classification of reflexes 
Milieu of the central nervous system 
The motor system
Physiology of the muscle contraction 
The neural control of movements 
Muscle tone and its control 
Motor functions of the spinal cord, brain stem, basal ganglia and the cerebellum 
Cortical control of motor functions 
The autonomic nervous system
Characteristics of sympathetic and parasympathetic action 
The sensory physiology
Signal transformation in receptor cells and coding 
Somatic sensations 
Perception of pain 
Function of the auditory system 
The vestibular apparatus 
Function of the visual system 
The sense of taste and smell 
Integrative function of the CNS
Function of the spinal cord 
Function of the limbic system 
Function of the cerebral cortex 
Intellectual functions of the brain, language 
Mechanism of learning and memory 
Waking and sleeping 
Bioelectrical activity of the CNS 

Practicals:
Membrane Potential, Model  
Tests for Hemosthasis 
Blood Groups Evaluation 
Hemoglobin and Hematocrit Estimation 
Sedimentation of Erythrocytes 
Blood Pressure Measurement 
Spirometry  
Evaluation of Reflexes 
Evaluation of Vision 
Hearing Tests
Education plan -
Schedule semestral
Educational week Date From - To Education type Theme Teacher Files Note Hodnocení
102.10.202310:45 - 12:15lectureMedical Physiology, History of the Subject  
03.10.202312:30 - 14:00lectureIntroduction to Cardiopulmonary Physiology  
06.10.202312:30 - 14:00lectureCellular Physiology, Cell Organelles  
210.10.202312:30 - 14:00lectureCell Membranes doc. MUDr. Vladimír Riljak, Ph.D.Please find attached my keynote presentations for “General Neurophysiology”. For the lectures of mine look into the part “Membrane potentials summary” and “Membrane potential”. Rest is non-obligatory and should offer you the concept of the whole topic.
13.10.202312:30 - 14:00lectureMembrane Transport  
316.10.202310:45 - 12:15lectureIon Channels 
17.10.202312:30 - 14:00lectureMembrane Potentials and their Propagationdoc. MUDr. Vladimír Riljak, Ph.D. 
20.10.202312:30 - 14:00lectureSignal Transduction  
424.10.202312:30 - 14:00lectureReceptors and Information Molecules 
27.10.202312:30 - 14:00lectureCytoskeleton, Cell Junctions, Extracellular Matrix 
530.10.202310:45 - 12:15lectureCell Cycle, Tissue Maintenance 
31.10.202312:30 - 14:00lecturePrinciples of Homeostasis, Blood, Plasma  
03.11.202312:30 - 14:00lectureBlood Cells, Hemopoiesis  
607.11.202312:30 - 14:00lectureHemostasis and Blood Coagulation 
10.11.202312:30 - 14:00lectureBody Defence System 
713.11.202310:45 - 12:15lectureRespiration. Pulmonary Ventilation 
14.11.202312:30 - 14:00lectureDiffusion, Perfusion, Pulmonary Circulation  
17.11.202312:30 - 14:00nothingState Holliday  
821.11.202312:30 - 14:00lectureGas Transport and Exchange 
24.11.202312:30 - 14:00lectureRegulation of Respiration, Respiration in Hypobaric and Hyperbaric Conditions 
927.11.202310:45 - 12:15lectureCirculation, Heart, Electrical Activity in the Heart 
28.11.202312:30 - 14:00lectureElectrocardiogram 
01.12.202312:30 - 14:00lectureCardiac Mechanics 
1005.12.202312:30 - 14:00lectureEvents of the Cardiac Cycle  
08.12.202312:30 - 14:00lectureArterial System 
1111.12.202310:45 - 12:15lectureMicrocirculation and Exchange, Veins and Venous Return  
12.12.202312:30 - 14:00lectureCardiovascular Control 
15.12.202312:30 - 14:00lectureSpecial Circulations  
1219.12.202312:30 - 14:00lecturePrinciples of Biological Regulation 
22.12.202312:30 - 14:00lecturePhysiology of the Digestive System, Motility 
1302.01.202412:30 - 14:00lectureSecretory Functions 
05.01.202412:30 - 14:00lectureDigestion, Absorption 
1409.01.202412:30 - 14:00lectureMetabolism, Minerals and Vitamins 
12.01.202412:30 - 14:00lectureSplanchnic Circulation, Functions of the Liver  
průměr: 3, hodnoceno: 1x
1515.01.202410:45 - 12:15lectureRegulation of Food Intake  
16.01.202412:30 - 14:00lectureFunction of the Skin  
19.01.202412:30 - 14:00lectureTemperature Regulation  
Schedule semestral
Educational week Date From - To Education type Theme Teacher Files Note Hodnocení
120.02.202412:30 - 14:00lectureKidney and Body Fluids, Fundamentals of Renal Physiology, Glomerular Filtration prof. MUDr. Jaroslav Pokorný, DrSc. 
21.02.202412:30 - 14:00lectureClearance, Tubular Processesprof. MUDr. Jaroslav Pokorný, DrSc. 
22.02.202410:30 - 12:00lectureKidney and their homeostatic roledoc. MUDr. Vladimír Riljak, Ph.D. 
227.02.202412:30 - 14:00lectureMechanisms for Controlling Extracellular Fluid Osmolality prof. MUDr. Jaroslav Pokorný, DrSc. 
28.02.202412:30 - 14:00lectureBody Acid-Base State and Its Regulation prof. MUDr. Jaroslav Pokorný, DrSc. 
29.02.202410:30 - 12:00lectureEndocrinology, The Cellular Biology of Endocrine System doc. MUDr. Vladimír Riljak, Ph.D. 
305.03.202412:30 - 14:00lectureNeurohypophyseal Hormones, Neuropeptides, Growth Factorsprof. MUDr. Jaroslav Pokorný, DrSc. 
06.03.202412:30 - 14:00lectureAdrenocortical and Thyroideal Hormones prof. MUDr. Jaroslav Pokorný, DrSc. 
07.03.202410:30 - 12:00lectureThyroid gland and Control of the Calcium and Phosphate Balance doc. MUDr. Vladimír Riljak, Ph.D. 
412.03.202412:30 - 14:00lectureAdrenal Medulla, Endocrine Rhythms prof. MUDr. Jaroslav Pokorný, DrSc. 
13.03.202412:30 - 14:00lectureAnterior Pituitary prof. MUDr. Jaroslav Pokorný, DrSc. 
14.03.202410:30 - 12:00lecturePancreas and Regulation of Carbohydrate Metabolism, Adipocytal Hormones doc. MUDr. Vladimír Riljak, Ph.D. 
519.03.202412:30 - 14:00lectureReproductive and Hormonal Functions of the Male, Sexual Differentiation prof. MUDr. Jaroslav Pokorný, DrSc. 
20.03.202412:30 - 14:00lectureReproductive and Hormonal Functions of the Femaleprof. MUDr. Jaroslav Pokorný, DrSc. 
21.03.202410:30 - 12:00lecturePregnancy and Lactation, Fetal and Neonatal Physiologydoc. MUDr. Vladimír Riljak, Ph.D. 
626.03.202412:30 - 14:00lectureGeneral Principles of Neuronal Functionsprof. MUDr. Jaroslav Pokorný, DrSc. 
27.03.202412:30 - 14:00lectureSynaptic Transmission, Neurotransmittersprof. MUDr. Jaroslav Pokorný, DrSc. 
28.03.202410:30 - 12:00nothingDean´s Day 
702.04.202412:30 - 14:00lectureMembrane Potentials, Integrative Function of Neuronal Circuitsprof. MUDr. Jaroslav Pokorný, DrSc. 
03.04.202412:30 - 14:00lectureSensory Processesprof. MUDr. Jaroslav Pokorný, DrSc. 
04.04.202410:30 - 12:00lectureIntroduction to Special Neurophysiologydoc. MUDr. Vladimír Riljak, Ph.D. 
809.04.202412:30 - 14:00lectureAuditory System prof. MUDr. Jaroslav Pokorný, DrSc. 
10.04.202412:30 - 14:00lectureGustation and Olfaction prof. MUDr. Jaroslav Pokorný, DrSc. 
11.04.202410:30 - 12:00lectureSensation system, Paindoc. MUDr. Vladimír Riljak, Ph.D. 
916.04.202412:30 - 14:00lectureSensory Processing prof. MUDr. Jaroslav Pokorný, DrSc. 
17.04.202412:30 - 14:00lectureControl of Movements, The Spinal Motor Control, Reflex Arc doc. MUDr. Vladimír Riljak, Ph.D. 
18.04.202410:30 - 12:00lectureStriated Muscle doc. MUDr. Vladimír Riljak, Ph.D. 
1023.04.202412:30 - 14:00lectureControl of the Posture Eye Position, Locomotion, Chewing prof. MUDr. Jaroslav Pokorný, DrSc. 
24.04.202412:30 - 14:00lectureVoluntary Movements, Motor Functions of Cerebral Cortex prof. MUDr. Jaroslav Pokorný, DrSc. 
25.04.202410:30 - 12:00lectureMotor Functions of Cerebellum and Basal Ganglia doc. MUDr. Vladimír Riljak, Ph.D. 
1130.04.202412:30 - 14:00lectureAutonomic Nervous System, Hypothalamus prof. MUDr. Jaroslav Pokorný, DrSc. 
01.05.202412:30 - 14:00nothingState holiday  
02.05.202410:30 - 12:00lectureLimbic System, Reward System, Smooth Muscledoc. MUDr. Vladimír Riljak, Ph.D. 
1207.05.202412:30 - 14:00nothingNo teaching  
08.05.202412:30 - 14:00nothingState holiday  
09.05.202410:30 - 12:00lectureIntegrative Functions of the Central Nervous System doc. MUDr. Vladimír Riljak, Ph.D. 
1314.05.202412:30 - 14:00nothingRector´s Day  
15.05.202412:30 - 14:00lectureIntegrative Functions of the Cerebral Cortex in Humansprof. MUDr. Jaroslav Pokorný, DrSc. 
16.05.202410:30 - 12:00lectureLearning and Memory doc. MUDr. Vladimír Riljak, Ph.D. 
1421.05.202412:30 - 14:00lectureAssociation Functions of the Cerebral Cortex Cognitive functions prof. MUDr. Jaroslav Pokorný, DrSc. 
22.05.202412:30 - 14:00lectureMilleu of the CNS, Blood Brain Barrier prof. MUDr. Jaroslav Pokorný, DrSc. 
23.05.202410:30 - 12:00lecturePhysiology of Behaviordoc. MUDr. Vladimír Riljak, Ph.D. 
1528.05.202412:30 - 14:00lectureBody Rhythms prof. MUDr. Jaroslav Pokorný, DrSc. 
29.05.202412:30 - 14:00lectureWaking and Sleeping doc. MUDr. Vladimír Riljak, Ph.D. 
30.05.202410:30 - 12:00lectureConsultations doc. MUDr. Vladimír Riljak, Ph.D. 
 
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