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Course, academic year 2023/2024
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Technology of Natural Drugs - GAF236
Title: Technology of Natural Drugs
Guaranteed by: Department of Pharmacognosy and Pharmaceutical Botany (16-16230)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2023
Semester: summer
Points: 0
E-Credits: 3
Examination process: summer s.:written
Hours per week, examination: summer s.:28/14, C+Ex [HS]
Capacity: unlimited / unlimited (20)
Min. number of students: 5
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Explanation: (F 3.r.)
Note: deregister from the exam date if a requisite was not fulfilled
course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: PharmDr. Daniela Suchánková, Ph.D.
In complex pre-requisite: GAF1002, GAF1004
Annotation -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)
Technology of Natural Drugs deals with procedures and equipment used for processing of medicinal plants and herbal drugs, for the extraction, isolation and purification of pharmaceutically important natural substances, and for the quality control of raw materials and final products. Attention is also paid to pharmacopoeial regulations and principles of good manufacturing practice.
Course completion requirements -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)

exam
Literature -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)

Obligatory:

  • Samuelsson, Gunnar. Drugs of natural origin : a textbook of pharmacognosy. Stockholm: Swedish Pharmaceutical Society, 1999, 551 s. ISBN 9789186274818.

  • EDQM. European Pharmacopoeia 9.0-9.5. Strassbourg: EDQM, 2017, s. ISBN 9789287183330.

  • . . In . český lékopis . Praha: Praha: Grada Publishing, a.s., 2017, s. -. ISBN 978-80-271-0500-7..
Syllabus -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)

  • Use and processing of medicinal plants. Natural substances in the therapy.

  • Sources of natural substances.

  • Production of medicinal plants.

  • Factors influencing constituents of herbal drugs.

  • Preservation of medicinal plants.

  • Storage of medicinal plants and herbal drugs.

  • Pests and contamination of herbal drugs; aflatoxins.

  • Quality control of herbal drugs.

  • Technological processing of herbal drugs for their further use. Procedures and equipment for cutting, grinding, and homogenization.

  • Manufacturing of herbal teas. Manufacturing process and quality control.

  • General principles of isolation of substances from plant material. Processing of crude drugs, extraction, concentration, refining, isolation – methods and equipment.

  • Industrial isolation of natural substances – development of an isolation method, manufacturing of simple standardized extracts and refined extracts.

  • Isolation of some pharmaceutically important substances – galantamine, paclitaxel, ergot alkaloids, lanatoside C, digoxin, anthocyanins, and silymarin.

  • Natural substances in modern pharmacy. Secondary metabolites of microorganisms. Drugs produced by means of biotechnological methods. Biopharmaceuticals.

  • Legislation aspects of medicinal plants and food supplements. Medicinal plants in European Union. Regulation on nutrition and health claims made on foods. Traditional herbal medicinal products and European Union herbal monographs.
Teaching methods -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)

Lectures and practical classes.
Requirements to the exam -
Last update: PharmDr. Daniela Suchánková, Ph.D. (19.02.2024)

To pass credit for practical classes.

The exam is written. Its content is based on the lectured material and written materials, which are placed for students in the Study Materials on the website of the faculty - Department of Pharmacognosy and pharmaceutical botany - Technology of Natural drugs. The test has 22-25 questions, partly of a quiz nature and partly of a descriptive nature (1-5 words); Each quiz question has 4 possible answers, of which 1-2 are correct.

1) Each correctly ticked answer is scored 1 point.

2) If someone ticks 3-4 of the 4 possible answers to the question, he gets 0 points for this question !!!

Classification

Required % of successful answers

failed

< 65

3

65,01 – 78,00

2

78,01 – 90,00

1

90,01 – 100,00

 
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