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Immunodeficiency II.pdf | Immunodeficiency. second part | MUDr. Dana Čechová |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (06.09.2019)
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (06.09.2019)
The application of basic immunology mechanisms and components in the clinical immunology and allergology, differential diagnostics and therapy. |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (06.09.2019)
The structure, mechanisms and function of the immune system. Immunopathologic reactions, inflammation, basic immunologic diagnoses (immunodeficiency, autoimmune diseases, allergy), transplantations. Clinical microbiology in association to immune dysfunctions. Diagnostic process, laboratory tests, treatment. |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (22.09.2022)
Chapel, H. et al.: Essentials of Clinical Immunology. Blackwell Publishing, 2006 and new editions. |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (22.09.2023)
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (02.09.2021)
Credit from Basic Immunology. Prerequisities. |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (02.09.2021)
prerequisities |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (22.09.2023)
Credit: presence form of education: activity during seminars, presence min. 90%. Examination: oral in person, 3 questions |
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Last update: MUDr. Mgr. Jitka Petanová, CSc. (22.09.2023)
Examination: oral (in person), 3 questions (1 question from topic I, 2 questions from topic II). Terms of examination: week after the block, exam. period (January, February, June).
Examination topics: I. Basic imunology 1. Basic characteristic of the innate immunity 2. Effector cells of the innate immunity 3. Humoral components of the innate immunity 4. Phagocytosis 5. Natural killer cells 6. Dendritic cells and their importance (+ clinical use) 7. Cytokines - basic characteristic. Functional groups, examples 8. Proinflammatory cytokines (+ clinical importance and use) 9. Complement system 10. Basic characteristic of the adaptive immunity 11. Antigen presenting cells 12. Recognition of the antigen by T cells and by B cells - the difference 13. Activation of B lymphocytes and T lymphocytes 14. Specific cytotoxic reaction 15. Immunoglobulins. Functions of antibodies 16. Interaction between cells 17. Mucosal immunity (structure and function); oral tolerance 18. Inflammation (inflammatory reaction, compounds, phases) 19. Immunological tolerance (central, peripheral) 20. Hypersensitivity reaction type I 21. Hypersensitivity reaction type II 22. Hypersensitivity reaction type III 23. Hypersensitivity reaction type IV 24. Antireceptor antibodies 25. Transplantation, graft rejection and its prevention. 26. Transplantation, graft versus host reaction 27. Defence to extracellular and intracellular pathogens - comparison
II. Clinical immunology and allergology (pathogenesis, clinical signs, examples of diseases, basic diagnostic and therapeutic possibilities) 1. Antitumor immunity, therapy 2. Clinical and laboratory signs of inflammation 3. Chronic inflammation and its complications 4. Primary antibody immunodeficiency 5. Primary cellular immunodeficiency 6. Complement dysfunctions 7. Phagocytic dysfunctions 8. Secondary immunodeficiency 9. Diagnostics of immunodeficiency (clinical, laboratory methods) 10. Organ specific autoimmune diseases - basic characteristic, examples 11. Systemic autoimmune diseases - basic characteristic, examples 12. Systemic lupus erythematosus 13. Sjogren´s syndrome 14. Antiphospholipid syndrome 15. Vasculitis - basic classification, clinical symptoms 16. Laboratory tests for diagnostic of autoimmune diseases 17. Anaphylactic and anaphylactoid reaction, treatment 18. Allergic rhinoconjunctivitis - pathogenesis, symptoms, treatment 19. Allergy and bronchial asthma 20. Food allergy, food intolerance 21. Drug allergy 22. Diagnostic of allergic diseases 23. Immunomodulation 24. Therapeutic use of immunoglobulins 25. Monoclonal antibodies and their use (in diagnostic and therapy) 26. Groups of immunosuppressive drugs 27. Therapy of allergic diseases 28. Passive and active immunization, adjuvants 29. Immunopathologic states in haematology 30. Immunopathologic states in neurology 31. Immunopathologic states in respiratory system 32. Immunopathologic states in otorhinolaryngology 33. Immunopathologic states in gastroenterology 34. Immunopathologic states in dermatology 35. Immunopathologic states in nephrology 36. Immunopathologic states in reproduction |
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