; - GAF385

• Title: Methods of Organic Structure Elucidation
• Guaranteed by: Department of Organic And Bioorganic Chemistry (16-16120)
• Faculty: Faculty of Pharmacy in Hradec Králové
• Actual: from 2023
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Hours per week, examination: summer s.:0/28, C [HS]
• Capacity: unknown / unlimited (30)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: deregister from the credit exam date if a requisite was not fulfilled; course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: PharmDr. Petr Matouš, Ph.D.
• Pre-requisite : GAF301

Annotation

Last update: PharmDr. Petr Matouš, Ph.D. (15.02.2024)

The subject is both theoretical (deepening of knowledge of spectral methods, especially NMR, then MS, IR and other methods used in many areas of chemical research), and practical (evaluation of NMR, IR, MS, ... data with an emphasis on identification of unknown compounds, correct interpretation and recording of characterization according to scientific standards). Students completing this subject will be prepared for the following scientific activity (diploma thesis, postgraduate studies, ...) and future career (pharmaceutical industry).

Course completion requirements

Last update: PharmDr. Petr Matouš, Ph.D. (15.02.2024)

The subject will not be opened in the academic year 2023/24

Syllabus

Last update: PharmDr. Petr Matouš, Ph.D. (15.02.2024)

Theoretical part:

• properties of matter, separation, izolation of compounds
• NMR, IR, MS, HR-MS, CHN analysis, polarimetry
• X-ray crystallography
• EMS, circular dichroism
• identification of chiral compounds

Practical part:

• interpretation of 1D NMR spectra
• interpretation of IR and MS spectra
• interpretation of other data (chiral compounds, dr, de, er, ee, etc.)
• identification of unknown compounds
• characterization of coumpounds