|
|
|
||
Last update: RNDr. Róbert Šuťák, Ph.D. (18.03.2019)
|
|
||
Last update: RNDr. Helena Kulíková (18.03.2019)
J. Marr, M. Müller: Biochemistry and Molecular Biology of Parasites, Academic Press, London 1995 |
|
||
Last update: RNDr. Róbert Šuťák, Ph.D. (18.03.2019)
80% účast na praktických cvičení + zápočet (odevzdání zpracovaných protokolů); písemný test |
|
||
Last update: RNDr. Róbert Šuťák, Ph.D. (18.03.2019)
1. Adaptation of metabolism of parasites to the host - oxidative stress, anaerobiosis, host-parasite competition for essential substances 2. Metabolism of selected anaerobic unicellular parasites – Entamoeba, Trichomonas, Giardia; effects of chemotherapeutics 3. Metabolism of selected unicellular parasites – trypanosomes, leishmanias; effects of chemotherapeutics 4. Metabolic specificity of intracellular parasitism – Trypanosoma cruzi, Plasmodium spp. 5. Metabolism of selected multicellular parasites – helminths, invertebrate parasites 6. Unusual properties of genetic information of parasitic protists – genome size, organellar genomes, splicing, and editing 7. Diagnosis of parasitic infections by molecular biology methods – PCR, ELISA 8. Entering of parasites into the host, its tissues and cells – molecular and biochemical mechanisms 9. Escape strategies of parasites – intracellular parasitism, molecular mimicry, antigenic variability 10. Host manipulation by parasites – influencing the immune system, changes in host metabolism, behavioral changes 11. Parasites as model organisms – possibilities of studying parasites in laboratory conditions |