It is an interdisciplinary cross-curricular subject that summarizes the essential aspects of the molecular biology of
malignant tumors and puts them in the context of their clinical behavior, course of the disease and response to
treatment. Each topic covers basic biological facts and principles, their specific application in the development of
oncological diseases, method of detection, possibilities of use in the diagnosis and treatment of tumors.
Syllabus
Last update: Marcela Holanová (12.07.2023)
1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells
2. Genetic predispositions, hereditary cancer syndromes
3. Cell signaling, growth factor receptor pathways
4. DNA damage and repair, epigenetic alterations
5. Cell cycle, ploidy, chromosomal aberrations
6. Apoptosis, cell immortalization
7. Cancer cell metabolism
8. Tumor radiobiology
9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs
10. Immune response, tumor microenvironment, microbiome
11. Methods in molecular biology, predictive testing, tumor molecular classification
12. Molecular-based therapy, gene therapy
Education plan -
Schedule by date
Day
Date
Description
Teacher
Files
Note
Hodnocení
Wednesday
06.03.2024
14:00 - 15:30
1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells
2. Genetic predispositions, hereditary cancer syndromes
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Wednesday
13.03.2024
14:00 - 15:30
3. Cell signaling, growth factor receptor pathways
4. DNA damage and repair, epigenetic alterations
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Wednesday
20.03.2024
14:00 - 15:30
5. Cell cycle, ploidy, chromosomal aberrations
6. Apoptosis, cell immortalization
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Wednesday
27.03.2024
14:00 - 15:30
7. Cancer cell metabolism
8. Tumor radiobiology
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Wednesday
03.04.2024
14:00 - 15:30
9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs
10. Immune response, tumor microenvironment, microbiome
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Wednesday
10.04.2024
14:00 - 15:30
11. Methods in molecular biology, predictive testing, tumor molecular classification
12. Molecular-based therapy, gene therapy
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
Rozpis datumový
Den
Datum
Popis
Učitel
Soubory
Poznámka
Hodnocení
Středa
06.03.2024
14:00 - 15:30
1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells
2. Genetic predispositions, hereditary cancer syndromes
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Středa
13.03.2024
14:00 - 15:30
3. Cell signaling, growth factor receptor pathways
4. DNA damage and repair, epigenetic alterations
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Středa
20.03.2024
14:00 - 15:30
5. Cell cycle, ploidy, chromosomal aberrations
6. Apoptosis, cell immortalization
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Středa
27.03.2024
14:00 - 15:30
7. Cancer cell metabolism
8. Tumor radiobiology
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Středa
03.04.2024
14:00 - 15:30
9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs
10. Immune response, tumor microenvironment, microbiome
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090
průměr: 5, hodnoceno: 1x
Středa
10.04.2024
14:00 - 15:30
11. Methods in molecular biology, predictive testing, tumor molecular classification
12. Molecular-based therapy, gene therapy
Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090