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Last update: T_FUUK (10.03.2004)
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Last update: HERMAN/MFF.CUNI.CZ (07.05.2008)
See annotation. |
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Last update: prof. RNDr. Petr Heřman, CSc. (30.10.2019)
Oral exam. |
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Last update: T_FUUK (28.04.2008)
W.J.Moore, Fyzikální chemie, Praha, SNTL 1981
R.Ch. Cantor, P. R. Shimmel, Biophysical chemistry, W.H. Freeman & Co., San Francisko, 1980
B.Alberts,O.Bray, J.Lewis, M.Raff, K.Roberts, J.O. Watson, Molecular Biology of the Cell, Garland Publishing, Inc., New York, London, 1989
G.G.Hammes, Enzyme catalysis and regulation, Academic Press, New York, London, 1982
W.Hoppe, W.Lohman, H.Markl, H.Ziegler, Biophysics, Springer-Verlag, Berlin, Heidelberg, New York, Tokyo, 1983
P.R. Bergethon, E.R. Simons, Biophysical chemistry, Springer-Verlag, NY, 1990
J. Horák, A. Kotyk, K.Sigler, Biochemie transportních pochodů, Academia, Praha 1984
V. Kalous, Z. Pavlíček, Biofyzikální chemie, SNTL, Praha 1984 |
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Last update: T_FUUK (12.05.2008)
lecture |
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Last update: prof. RNDr. Petr Heřman, CSc. (30.10.2019)
Oral exam, see syllabus. |
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Last update: T_FUUK (28.04.2004)
1. Thermodynamics of biochemical reactions Biological cycle, energy and order, chemical potentials, activity, chemical affinity, chemical reactions, kinetics and equilibria, temperature dependence, theory of the transient complex, reversible and chain reactions, compartmental analysi 2. Enzyme catalysis and regulation Chemical aspects of the enzyme catalysis, elementary steps, stady state kinetics, King-Altman method, one substrate one product, multiple substrates and products, regulation, allostery, models, effectors, inhibition, activation. 3. Membrane transport Passive and active transport, uniport, symport, antiport, transporters, termodynamic aspects of the active transport, pores and channels, membrane potential, osmotic stability, intracellular pH, transport of macromolecules and particles, regulation 4. Respiratory chain Structure and function of mitochondria, production of ATP, proton gradient 5. Photosynthesis Structure and function of chloroplasts, antenae systemes, reaction center, electron transport, proton gradients, phosphorylation, sugar synthesis 6. The nervous system Neurons, gated ion channels, action potential, neurotransmiters, postsynaptical potentials, synaptic modifications amd elliminations, grant postsynaptic potencial, adaptation, neuron networks 7. Vision Molecular basis of the photoreception, vizual pigments, photoreceptors, ion channels, vizual excitation and adaptation, differences for vertebrata and invertebrata, role of calcium 8. Active movement Muscle cells, actine and myosine, contraction role of calcium nad ATP, cellular and intracellular movement, microtubules, cilia
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