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Biochemistry III - MC280P24

Title:	Biochemie III (b)
Czech title:	Biochemie III (b)
Guaranteed by:	Department of Chemistry Education (31-280)
Faculty:	Faculty of Science
Actual:	from 2024
Semester:	winter
E-Credits:	2
Examination process:	winter s.:
Hours per week, examination:	winter s.:2/1, C+Ex [HT]
Capacity:	25
Min. number of students:	2
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	Czech
Level:	specialized
Additional information:	https://dl2.cuni.cz/course/view.php?id=1463
Note:	enabled for web enrollment priority enrollment if the course is part of the study plan

Guarantor:	doc. RNDr. Václav Martínek, Ph.D.
Teacher(s):	doc. RNDr. Václav Martínek, Ph.D.
Incompatibility :	MC280P24B

Opinion survey results Examination dates WS schedule E-learning course

Annotation -

Biochemistry III (b) is aimed at older students of the Master's program of Teacher Education of Chemistry. The lecture should help students prepare for the final exam in biochemistry at the Department of Chemical Education.
The lecture deals with the area of general biochemistry in the context of the main topics of the national RVP framework program.

Last update: Martínek Václav, doc. RNDr., Ph.D. (25.10.2019)

Literature -

Color Atlas of Biochemistry - Koolman J. et al. 2nd edition 2005

Fundamentals of Biochemistry - Voet et al. 2nd edition 2006

Biochemistry - Stryer et al. 7th edition 2007

Last update: Rubešová Jana, RNDr., Ph.D. (27.04.2017)

Requirements to the exam -

At least 80% attendance and presentation of the biochemistry topic is required for credit. The exam is a combination of a written comprehensive exam and an oral exam.

Last update: Martínek Václav, doc. RNDr., Ph.D. (23.09.2024)

Syllabus -

• The composition of living matter, water, cell, viruses, cytoskeleton

• Carbohydrates: classification, structure, function

• Amino acids: classification, structure, properties, peptides

• Proteins: structure, distribution, complex proteins

• Enzymes: classification, reaction equilibrium, enzyme kinetics, inhibition, regulation (allosteric)

• Nucleic acids: building blocks, types, structure

• Replication, transcription, translation, protein synthesis

• Lipids and biomembranes: classification, properties and function, metabolism (β-oxidation), biosynthesis, bile acids, ketone bodies

• Vitamins, cofactors and "macroergic 'compounds, muscle contraction

• Glycolysis, gluconeogenesis, Pentose cycle

• Oxidative decarboxylation, citric acid cycle, respiratory chain (oxidative vs substrate phosphorylation)

• Basic relations in metabolism, classification of organisms, catabolism, anabolism

• Human biochemistry I: digestion (enzymes), proteolysis, proteases, blood (O2 transport, hemoglobin, erythrocyte)

• Human biochemistry II: hormones, nervous system (neurotransmitters), signaling molecules, metabolism of xenobiotics

• Photosynthesis, Calvin Cycle, C3, C4 and CAM plants

Last update: Rubešová Jana, RNDr., Ph.D. (27.04.2017)

Learning outcomes -

    The student identifies the basic composition of living organisms and their key components.
    The student analyzes the structure and function of carbohydrates in biological processes.
    The student distinguishes different types of amino acids and their properties, including the structure of peptides.
    The student describes the structure and distribution of proteins, including folded proteins.
    The student explains the mechanisms of enzymes, including reaction equilibria and kinetics.
    The student investigates the building blocks of nucleic acids and their structure.
    The student demonstrates the processes of replication, transcription, and translation in proteosynthesis.
    The student evaluates the properties and functions of lipids and biomembranes, including metabolism.
    The student evaluates the role of vitamins and cofactors in metabolic processes.
    The student applies knowledge of glycolysis, gluconeogenesis, and the pentose cycle.
    The student interprets the processes of oxidative decarboxylation and the citrate cycle.
    The student compares basic metabolic relationships between catabolism and anabolism.
    The student analyzes the enzymatic processes of digestion and oxygen transfer in the blood.
    The student examines the role of hormones and neurotransmitters in the nervous system.
    The student explains the mechanisms of photosynthesis and the Calvin cycle in plants.

Last update: Martínek Václav, doc. RNDr., Ph.D. (23.09.2024)