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Last update: KROUTIL (19.04.2006)
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Last update: RNDr. Martin Štícha, Ph.D. (27.10.2019)
Mass spectrometry for chemists and biochemists, Johnstone Robert A. Mass spectrometry, Gross J. H. |
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Last update: RNDr. Martin Štícha, Ph.D. (27.10.2019)
The study is completed with an exam in the form of a written test of 60 minutes. The test consists of 4 questions. Each question is rated 5 points. The minimum number of points required to pass the exam is 12 (60%).
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Last update: KROUTIL (19.04.2006)
Introduction. Experimental design of mass spectrometer. Survey of ionization techniques. Electron impact ionization. Chemical ionization. Other ionization techniques. Mass analyzers. Magnetic mass analyzer. Electric analyzer. Quadrupole analyzer. Ion trap. Time of flight analyzer. Detectors. Multipliers. Scintilation photomultipliers. Mass spectrum. Molecular ion. Analysis of isotopic composition. Stable izotopes. Determination of number of rings plus double bonds from elemetal formula. Theory of fragmentation. Charge and unpaired electron localization in molecular ion. Molecular ion fragmentation, fragmentation paths. Mechanisms of fragmetation of organic molecules. Sigma bond dissociation. Alfa cleavage initiated by radical-site. Cleavage initiated by charge-site. Decompositions of cyclic structures. Rearrangements. Radical-site rearrangements. Charge-site rearrangements. |