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Course, academic year 2023/2024
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Biochemistry I - MC250P40A
Title: Biochemie I (kata)
Czech title: Biochemie I (kata)
Guaranteed by: Department of Biochemistry (31-250)
Faculty: Faculty of Science
Actual: from 2020 to 2023
Semester: summer
E-Credits: 6
Examination process: summer s.:
Hours per week, examination: summer s.:3/2, C [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Note: enabled for web enrollment
Guarantor: prof. RNDr. Helena Ryšlavá, CSc.
Teacher(s): RNDr. Michaela Čermáková, Ph.D.
prof. RNDr. Jiří Hudeček, CSc.
prof. RNDr. Helena Ryšlavá, CSc.
RNDr. Dagmar Svášková, Ph.D.
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Annotation -
The course is intended for students of "Clinical and toxicological analysis", it is the first half of a two-semester course.
Introduction, basic terms and principles of biochemistry. Biomolecules (proteins, saccharides, lipids and nucleic acids) - their structure and biochemical properties. Enzymes - properties, structure, coenzymes and cofactors. Bioenergetics - thermodynamic principles, macroergic compounds.
Basic methodology of biochemistry (isolation and purification of biomolecules, laboratory animals, immunochemical methods, microscopy
Lectures - in Czech (English possible).
Last update: Hudeček Jiří, prof. RNDr., CSc. (17.02.2014)
Literature -

J. M.Berg, J. L. Tymoczko, L. Stryer: Biochemistry, 6th Ed., W. H. Freeman and Co., N.Y. 2007; D. Voet, J.G. Voet: Biochemistry, Wiley, N.Y. 1995; R.H. Garrett, C.M. Grisham: Biochemistry, Saunders Col. Publ., N.Y. 1995, D. L. Nelson, M. M. Cox: Lehninger Principles of Biochemistry. 5th Ed.,  W. H. Freeman and Co., N.Y. 2008.

 

Last update: Hudeček Jiří, prof. RNDr., CSc. (17.02.2014)
Requirements to the exam -

Credit: active participation in seminars, tests. For English-speaking students (Erasmus), specific conditions might be negotiated (because of their frequent later arrival).

Last update: Svášková Dagmar, RNDr., Ph.D. (22.02.2024)
Syllabus -

Structure of living cell and biochemical function of organelles. Molecular components of cell (amino acids, peptides, proteins, carbohydrates, lipids, nucleic acids), their structure, chemical and biochemical properties. Enzymes - structure of enzyme molecule, enzyme properties, kinetics of enzyme reaction, regulatory enzymes. Basic biochemical methodology: arrangement of the work in biochemical laboratories, organization of chemical literature, evaluation of results. Isolation and purification of biomolecules, seperation methods, electromigration. Laboratory animals. Immmunochemical methods, microscopy.



Last update: Hudeček Jiří, prof. RNDr., CSc. (17.02.2014)
Entry requirements - Czech

Základní znalosti obecné, anorganické a fyzikální chemie a základní matematické dovednosti (na úrovni kvalitního absolventa střední školy). 

Last update: Hudeček Jiří, prof. RNDr., CSc. (17.02.2014)
 
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