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Last update: prof. RNDr. Danuše Sofrová, CSc. (04.10.2010)
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Last update: RNDr. Marek Vrbacký, Ph.D. (29.09.2015)
Bioenergetics; David G. Nicholls, Stuart J. Ferguson 4th edition, Academic Press, 2013
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Last update: RNDr. Marek Vrbacký, Ph.D. (08.11.2011)
Znalost látky (tematické okruhy viz sylabus) v rozsahu přednášek. Zkouška je písemná a její součástí je problémová úloha. Posluchačům jsou k dispozici prezentace z přednášek. Plnotextová verze doporučené učebnice Bioenergetics 3 je dostupná ze sítě PřF: http://www.sciencedirect.com/science/book/9780125181211 |
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Last update: prof. RNDr. Danuše Sofrová, CSc. (04.10.2010)
Thermodynamics of life. Gibbs energy. Oxidation-reduction (redox) potential.
High-energy compounds. Central role of ATP. Biological redox reactions. Redox membrane carriers. Basic types of metabolism.
History and perspective of bioenergetics. Peter Mitchell in his chemiosmotic hypothesis.
Structure of mitochondria and biological membranes. Mitochondrial proteome.
Membrane transport. Mitochondrial shuttle mechanisms.
Oxidative decarboxylation of 2-oxoacids.
Citric acid (Krebs) cycle, glyoxylate cycles.
Lipids metabolism.
Respiratory chain, aerobic phosphorylation.
Mitochondrial genetics and pathology.
Respiratory chain and primary stage of photosynthesis: shared and unique features, electron and proton transport pathways. Light-harvesting complexes.
Secondary stage of photosynthesis - Calvin cycle, photorespiration, C3, C4 and CAM plants. Photosynthesis regulation.
Other biosynthetic processes in photoautotrophs (gas nitrogen fixation, assimilation of nitrate and sulphate). |