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The course entitled Biochemistry and Biology of Microorganisms is dealing with the important issue of investigation, interaction (effect) and application of microorganisms with a special attention to bacteria. Beside the detailed explanation of microorganism genetics and biochemistry, the lecture makes students familiar with microorganism handling, cultivation procedures and principles of their molecular-biology applications. In the context of a bacterial morphology and taxonomy, medical consequences of human-bacteria interactions (pathogen classification, mechanism of antibiotic action) and biotechnology applications (industry and food production) are covered. The knowledge gained in the basic Biochemistry course is recommended and expected.
Lectures - in Czech - Last update: Hodek Petr, prof. RNDr., CSc. (14.02.2017)
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Zubay, G.: Origin of Life on the Earth and in the Cosmos, WCB Publishers, Boston, 1996.
Lecture handouts are available on Moodle: http://dl2.cuni.cz/course/view.php?id=1282 Last update: Hodek Petr, prof. RNDr., CSc. (09.09.2014)
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písemný test, hodnocení: 100-87% výborně, 86-73% velmi dobře, 72-60% dobře Last update: Osičková Adriana, Ing., Ph.D. (04.02.2021)
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A. History Question of origin and evolution of live Significant discoveries of microbiology
B. Biology of microorganisms Bacterial cell vs. other microorganisms Bacterial cell morphology, growth and cell division, sporulation Taxonomy, nomenclature, systematics
C. Biochemistry of microorganisms Classification based on source of carbon and energy Energy metabolism, photosynthesis Alternative metabolism pathways Transport, element cycle
D. Microbial genetics DNA, RNA, replication, transcription, translation Regulation, cell cycle Plasmids, viruses, transposomes Principles of molecular-biology applications
E. Medical microbiology Disease, pathogens, symbionts Sterilization, chemotherapy, and antibiotics
F. Applied microbiology Industry and food production application
G. Basic principles of handling with microorganisms Last update: Liberda Jiří, RNDr., Ph.D. (18.09.2009)
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