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Course, academic year 2023/2024
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Chemical Sensors and Biosensors - MC230P16
Title: Chemické sensory a biosensory
Czech title: Chemické sensory a biosensory
Guaranteed by: Department of Analytical Chemistry (31-230)
Faculty: Faculty of Science
Actual: from 2020
Semester: summer
E-Credits: 2
Examination process: summer s.:combined
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Note: enabled for web enrollment
Guarantor: RNDr. Hana Dejmková, Ph.D.
Teacher(s): RNDr. Simona Baluchová, Ph.D.
RNDr. Hana Dejmková, Ph.D.
Annotation -
Overview of principles and designs of chemical sensors and biosensors. Definition of chemical sensor and its basic static and dynamic parameters. Electrochemical sensors with liquid electrolyte. Solid-state electrochemical sensors. Sensors based on measurement of electron conductivity. Calorimetric sensors. Mass-sensitive sensors. FET sensors. Optical sensors.
Last update: OPEKAR (29.01.2003)
Literature -

Sensors. A Comprehensive Survey (Eds. W.Göpel, J.Hesse, J.N.Zemel), Vols.2, 3, VCH, Weinheim, 1991.

Last update: Nesměrák Karel, doc. RNDr., Ph.D. (28.10.2019)
Requirements to the exam -

The course is concluded by elaborating and giving a 10-15 minute presentation on a drawn topic from the issue of chemical sensors.

Last update: Nesměrák Karel, doc. RNDr., Ph.D. (28.10.2019)
Syllabus -

1. Definition of chemical sensor and its basic scheme: molecular/ionic selector, physical-chemical interaction, physical transducer (regulator). Comparison of properties of a physical (artificial) and biological (human) sensors.

2 .Basic parameters characterizing (chemical) sensors properties: static parameters - response, dynamic range, sensitivity, selectivity; dynamic parameters - response rate, time constant.

3. Sensors based on different physical-chemical principles - a survey:

  • electrochemical sensors with liquid electrolyles (liquid-state sensors);

  • solid-state elelectrochemical sensors;

  • field effect transistor (FET) based sensors;

  • electronic conductance sensors;

  • calorimetric sensors;

  • mass-sensitive sensors;

  • optochemical/photochemical sensors.

3.1. Electrochemical sensors with liquid electrolytes:

Potentiometric sensors (ISE, coated wires), gas sensors (Severinghaus type, air-gap, potentiometric biosensors).

Amperometric sensors (wall-jet, thin-layer, tubular), gas sensors (Clark type, amperometric biosensors). Function of porous and nonporous membrane in chemical sensors

3.2. Electrochemical sensors with solid electrolytes:

ZrO2 sensors (lambda sensors, oxygen pump);

Sensors with proton conductors;

Solid-state sensors containing an active layer.

3.3. FET - based sensors:

Ion selective FET (ISFET);

Chemically selective FET (CHEMFET);

Work function sensors.

3.4. Electronic conductance sensors:

Metaloxide (SnO2) sensors (TGS, Figaro);

Chemiresistors (with inorganic active layer, with metalophtalocyanine layer, with conducting organic polymers);

Multisensors, electronic nose (pattern recognition analysis).

3.5. Calorimetric sensors:

Pelistors, pyroelectric sensors;

Heat conductivity based sensors.

3.6. Mass sensitive sensors (piezoelectric crystal / chemically sensitive layer):

bulk acoustic wave - BAW (or quartz crystal microbalance, QCM);

Surface acoustic wave sensor (SAW), application in biosensors.

3.7. Optical sensors:

Sensors with optical fibers (optody).

Last update: OPEKAR (09.01.2003)
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