Clinical Cases in Immunology - MB151P108
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The course is given in a 8-day run in summer semester
This course is targeted on general biology audience with an interest in immunology, genetics and human diseases. The aim of this course is to review, deepen and solidify your knowledge in immunopathology and clinical immunology by presenting and discussing authentic examples of patients suffering from diverse genetically inherited immune disorders. Each lecture features 3-4 different but related individual case studies, briefly describing patients’ symptoms, clinical examination, medical history, and therapeutic treatments. Based on this information we try to determine which part of the immune system is dysfunctional and diagnose the specific disease. We then discuss cellular and molecular mechanisms leading to the specific disorder, as well as possible genetic predisposition. We then compare how much the human phenotype resembles phenotypes in corresponding mouse models. Last update: Šebková Nataša, RNDr., Ph.D. (26.09.2024)
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Case Studies in Immunology: A Clinical Companion, Raif Geha, Luigi Notarangelo Last update: Gáliková Kristýna, Mgr. et Mgr., DiS. (12.03.2026)
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The examination will proceed at the end of the course using a Single best answer test - only one answer is the best. You will get 1 point for each correct answer. Grade 1 is for >85%, grade 2 is for >70%, grade 3 is for >55%. Last update: Drbal Karel, RNDr., Ph.D. (02.04.2024)
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Syllabus: 1) Immunodeficiencies Last update: Drbal Karel, RNDr., Ph.D. (02.12.2022)
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The aim of the course is for students to identify and classify key inborn errors of immunity, autoimmune disorders, or lymphoproliferative conditions based on the analysis of clinical case studies. Students will explain the molecular mechanisms of immune system dysfunction and apply this theoretical knowledge to the interpretation of clinical symptoms. Furthermore, students are able to analyze the relationships between genotype and phenotype, compare clinical disease manifestations in humans with mouse models, and evaluate the appropriateness of proposed therapeutic procedures. The learning outcome is the ability to independently recognize specific immunopathologies.
Last update: Šebková Nataša, RNDr., Ph.D. (24.02.2026)
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Předmět bude vyučován v angličtině, turnusově na konci června, a to v průběhu ca 2 týdnů. Odkaz na web učitele: https://www.weizmann.ac.il/immunology/Abramson/teaching Last update: Šebková Nataša, RNDr., Ph.D. (08.01.2026)
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