Medical Microbiology 2 - MB140P77E
Title: Medical Microbiology 2
Czech title: Lékařská mikrobiologie 2
Form of teaching: lecture+block practicals
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2025 to 2025
Duration in semesters: 1
Semester: winter
E-Credits: 5
Examination process: winter s.:combined
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Extent per academic year: 1 [weeks]
Capacity: unlimited
Maximum number of enrolled students: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: not taught
Language: English
Explanation: Přednášky i praktikum se konají na 1. Lékařské fakultě UK jako součást předmětu"Mikrobiologie 2“ a vyučovaného na 1. LF UK tj. Mikrobiologie 2 - B80382(Všeobecné lékařství AP)
Repeated enrollment: 2 / 2 / 2 / 2
Note: enabled for web enrollment
priority enrollment if the course is part of the study plan
Guarantor: MUDr. Emil Pavlík, CSc.
Mgr. Kateřina Petříčková, Ph.D.
doc. RNDr. Jan Bobek, Ph.D.
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Annotation -
Provides basic information on general and specialised human medical microbiology, virology, mycology and
parasitology. Describes important human pathogens, their characteristic properties, pathogenicity mechanisms of
the diseases they induce, and basics of the antibiotic, antifungal, antiviral and antioparasitic therapy of the
diseases. In practical hands-on learning provides important skills for bacteriological investigation of selected
samples. The student will learn technics for clinical specimen collection, strategy of microbial identification and
anti-microbial therapy.
Last update: Lichá Irena, RNDr., CSc. (18.03.2019)
Literature -

MURRAY P.R., ROSENTHAL K.S., PFALLER M.A. eds.: Medical Microbiology fifth edition, Mosby Inc. St. Louis 2006.

# KAYSER F.H., BIENZ K.A., ECKERT, J., ZINKERNAGEL R.M. eds.: Medical Microbiology, Georg Thieme Verlag Stuttgart-New York 2005.

Last update: Lichá Irena, RNDr., CSc. (18.03.2019)
Learning outcomes

After successful completion of the course, the student:

  • Defines the basic concepts of general and special microbiology, virology, and parasitology and outlines their significance in medicine.

  • Lists and distinguishes the main groups of human pathogens (bacteria, viruses, fungi, parasites) and identifies their fundamental biological characteristics.

  • Describes and compares the structure of bacterial, micromycete, and parasitic cells and explains the relationship between structure and function.

  • Describes the structure of viruses, their replication cycle, and explains virus–host cell interactions.

  • Defines the terms pathogenicity and virulence, identifies virulence factors of microorganisms, and provides examples of their effects. Defines and distinguishes bacterial toxins and superantigens and gives examples of their effects on the host.

  • Describes the basic types of bacterial metabolism, growth, and reproduction and interprets their significance for diagnostics and therapy.

  • Explains the principles of bacterial genetic information and describes the mechanisms of its transfer.

  • Describes and distinguishes the components of innate and adaptive antibacterial immunity and explains the relationships between the immune response and the course of infection.

  • Explains the basic mechanisms of inflammation and sepsis.

  • Describes the principles of passive and active immunization, categorizes types of vaccines, and evaluates their benefits and limitations.

  • Lists and compares physical and chemical methods of sterilization and disinfection and applies them in model situations.

  • Describes the structural types of anti-infective agents, explains their mechanisms of action, and distinguishes the basic mechanisms of resistance.

  • Explains the principles of antimicrobial susceptibility testing and evaluates their importance for therapeutic strategy.

  • Describes the physiological microbial flora of the human body, evaluates its significance, and explains the role of biofilms in clinical microbiology.

  • Describes the principles of proper collection of clinical specimens and applies them in laboratory diagnostics.

  • Lists and explains the basic methods for identification of bacteria, viruses, and parasites, including culture-based, serological, and molecular methods.

  • Summarizes basic diagnostic and therapeutic approaches to selected infectious diseases and justifies their choice.

  • Interprets the results of basic microbiological investigations (culture, PCR, serology, MALDI) in a clinical context.

  • Characterizes and classifies the main bacterial, mycotic, viral, and parasitic human pathogens and gives examples of the diseases they cause.

  • Provides an overview of the principal pathogens affecting individual organ systems (urinary tract, respiratory system, gastrointestinal tract, central nervous system, skin, genital tract).

  • Describes the specifics of nosocomial infections and evaluates their importance for clinical practice.

  • Explains the principles of biological weapons and assesses their risks in the context of bioterrorism.

Last update: Petříčková Kateřina, Mgr., Ph.D. (20.01.2026)
The course does not include work placement