SubjectsSubjects(version: 953)
Course, academic year 2023/2024
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Physiology of bacteria I - MB140P34
Title: Fyziologie bakterií I
Czech title: Fyziologie bakterií I
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2019
Semester: winter
E-Credits: 4
Examination process: winter s.:combined
Hours per week, examination: winter s.:3/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Level: basic
Note: enabled for web enrollment
Guarantor: doc. RNDr. Ivo Konopásek, CSc.
Teacher(s): doc. RNDr. Ivo Konopásek, CSc.
Pre-requisite : MB140P33
Is co-requisite for: MB140C34
Is pre-requisite for: MB140P32
Annotation -
The aim of the lecture is to give the student a comprehensive idea of ​​the structure and function of bacterial and archaea cells, which are the implementation of their genetic program depending on the changing environmental conditions.
Prerequisite of the course is Microbiology MB140P33I.
Last update: Konopásek Ivo, doc. RNDr., CSc. (22.04.2022)
Literature -

1. Kim B.H., Gadd, G.M.: Prokaryotic Metabolism and Physiology, Cambridge University Press, 2019, ISBN 978-1-316-62291-9

(Older edition: Kim B.H., Gadd, G.M.: Bacterial Physiology and Metabolism, Cambridge University Press, 2008,ISBN-10: 0521712300, ISBN-13: 978-0521712309)

2. Madigan, Martinko, Berger, Buckley, Stahl: Brock Biology of Microorganisms, Pearson; 15 edition (2017), ISBN-10: 9780134261928

Last update: Konopásek Ivo, doc. RNDr., CSc. (22.04.2022)
Requirements to the exam -

The exam is written. It is based on presentations of lectures and on compulsory literature.

Last update: Konopásek Ivo, doc. RNDr., CSc. (25.10.2019)
Syllabus -

1. Introduction - Physiology of bacteria Characteristics of bacteria and archea, History of bacteria physiology, Strategy in physiological research and genomic revolution, Model organism - Escherichia coli, Bacteria: laboratory pure cultures and bacterial communities

2. Structure and function of bacterial cell Chemical composition and structure of bacterial cell, DNA, nucleus and genomes of bacteria, Proteins, Flagella, pili and fimbriae, Cases, S-layers, Outer membrane of gram-negative bacteria, Cell wall and periplasmic space, Cytoplasmic membrane, Cytoplasm and cytoplasmic compartments

3. Transport in bacteria Transport in bacteria, lipids, membrane proteins, Ionophores as models Types of transport, diffusion, primary and secondary transport, ABC transporters, phosphotransferase system, precursor and product antiport, iron transport, Native protein conformation, chaperones and chaperonins, Protein transport to CPM, periplasms , OM, excretion of proteins into the environment,

4. Bacterial nutrition, energy, catabolism and anabolism. Bacterial nutrition, Glycolysis and its alternatives, Krebs cycle, Energy production and transformation in bacterial cell, Aerobic respiration

5. Biosynthesis and growth Molecular composition of bacteria, Nitrogen and sulfur assimilation, Biosynthesis of amino acids, nucleotides, lipids, Biosynthesis of cell wall structures, Individual cell growth, cell cycle, Growth of bacterial population, Continuous cultivation

6. Metabolic diversity Anaerobic fermentation, Anaerobic respiration, Chemolitotrophy, Phototrophy.  

Last update: Konopásek Ivo, doc. RNDr., CSc. (22.04.2022)
 
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