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Course, academic year 2023/2024
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Principles of genetics - MB140P16E
Title: Principles of Genetics
Czech title: Základy genetiky
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2022 to 2023
Semester: winter
E-Credits: 5
Examination process: winter s.:combined
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Capacity: 20
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Guarantor: doc. RNDr. Jiří Král, CSc.
RNDr. Michaela Schierová, Ph.D.
Teacher(s): doc. RNDr. Jiří Král, CSc.
RNDr. Michaela Schierová, Ph.D.
Is incompatible with: MB140P47, MB140P17
Annotation -
Last update: RNDr. Irena Lichá, CSc. (18.03.2019)
The course summarizes the main topics of classical and molecular genetics. The program of lectures is divided
into four blocks: 1) characterization of genetic material at the level of DNA, chromosomes and genome, 2)
principles of inheritance of qualitative and quantitative traits, 3) mutations, mutagens and repair systems 4)
population and evolutionary genetics. In addition, other topics are included in the lectures, such as the use of DNA
polymorphism in gene mapping and molecular taxonomy, methods of gene dose compensation for sex
chromosomes, oncogenetics and epigenetics.
Seminar is an integral part of the course. By solving theoretical tasks and by examining microscopic samples,
understanding the principles of genetic analysis will be improved.
Credit from the seminar: at least 50% points for solving theoretical tasks at least 50% attendance at seminars.
Depending on the difficulty, the task solutions are evaluated by a maximum of 4 points.

The exam is combined, includes the written test composed of 20 questions covering all presented topics. Each
answer is rated 0 - 5 points. Only students who got at least 60 points in the written test are allowed to the oral part of
exam. The condition for passing the exam is credit from seminar.
Literature -
Last update: RNDr. Jana Rubešová, Ph.D. (08.06.2022)

The essential study material for the exam are presentations available on Moodle.

Klug W.S., Cummings M.R., Spencer C.: Concepts of Genetics , Pearson Education, Inc., ,

Snustad D.P., Simmons M.J.: Principles of Genetics 2019 John Wiley and Sons, Inc., Hoboken,

Brooker RJ: Genetics: Analysis and Principles, 6th ed., McGraw-Hill Education, 2017

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