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Course, academic year 2023/2024
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Genetics for the students of Biology Education programmes - MB140P15U
Title: Genetika pro učitelské kombinace
Czech title: Genetika pro učitelské kombinace
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2020
Semester: summer
E-Credits: 4
Examination process: summer s.:combined
Hours per week, examination: summer s.:3/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Level: basic
Is provided by: MB140P11
Explanation: nahrazeno v nových plánech MB140P11
Additional information:
Guarantor: RNDr. Olga Rothová, Ph.D.
Teacher(s): RNDr. Olga Rothová, Ph.D.
Is incompatible with: MB140P11
Annotation -
The lecture is specifically designed for students of "Biology oriented at education" programmes. It introduces them to the
field of modern genetics, the knowledge of which is necessary for the understanding of the majority of other biological
subjects and areas. The lecture gives a summary of the basic genetic terms and rules, as well as of the contemporary trends
in genetics (extranuclear inheritance, epigenetic, molecular evolution ...). At the same time, it offers opportunity to discuss
the implications of the results of genetic research for the modern society (genetic diagnostics and gene therapy, forensic
genetics, genetic engineering of plants and animals etc.).
Last update: Rothová Olga, RNDr., Ph.D. (15.04.2008)
Literature -

Kočová M., Nováková M.: Vybrané úlohy ke cvičením z genetiky. Karolinum, Praha, 1997.

Kočárek E.: Genetika, Scientia, Praha, 2004.

Klug W.S., Cummings M.R., Spencer C.A.: Concepts of Genetics (8th ed.), Pearson Education, Inc., Upper Saddle River, NJ, 2006.

Russell P.J.: iGenetics. A Mendelian Approach. Benjamin Cummings, San Francisco, CA, 2006.

Griffiths A.J.F., Wessler S.R., Lewontin R.C., Gelbart W.M., Suzuki D.T., Miller J.H.: Introduction to Genetic Analysis (8th ed.). W.H.Freeman and Co., New York, 2005.

Last update: Rothová Olga, RNDr., Ph.D. (15.04.2008)
Requirements to the exam -

The exam is oral, it will take about half an hour, the content of lectures will be tested.

Last update: Schierová Michaela, RNDr., Ph.D. (24.10.2019)
Syllabus -

Cell division and reproduction of organisms

Haploidy-diploidy, basis of cytogenetics - chromosome, mitosis, meiosis, structure and behaviour of chromosomes during cell cycle, B chromosomes, spermatogenesis and oogenesis

Model organisms in biology and genetics

Basic concepts of genetics

Heredity and variability, gene, allele, genotype, phenotype, dominance - recessivity - co-dominance, principles of segregation and combination, lethality, gene interactions - types, causes and manifestations

Gene expression in prokaryotes and eukaryotes

Regulation of gene expression ? common attributes and differences, the effect of external and internal environment, developmental genetics, epigenetic regulation

Mutation and mutagenesis

Gene ? chromosome ? genome mutations, mutagenes, DNA repair, transposable elements, polyploidy ? eupolyploidy, aneuploidy, evolutionary role of mutations, process of speciation

Gene linkage

Recombination, crossing-over, linkage analysis, gene mapping

Genetic control of sex determination

Genetic and environmental sex determination in various organisms, lyonization, sex-linked, sex-limited and sex-influenced traits and their heredity

Extranuclear inheritance

Extranuclear genomes in the cell, their inheritance, interaction with nuclear genome, genomes of viruses and viroids

Quantitative genetics

Polygenic determination of traits, principles and methods of traditional and modern quantitative genetics, heritability

Human genetics

Pedigree analysis, examining twins, karyotype analysis, diagnostics of genetic diseases, gene therapy

Population and evolutionary genetics

Types of populations, Hardy-Weinberg´s law, genetic equilibrium forces that change gene frequencies in populations (selection, mutation, migration, genetic drift etc.)

Practical uses of genetics

Breeding and its methods (selection, mutagenesis, polyploidization, genetically modified organisms), forensic genetics, conservation genetics and endangered species programmes

Last update: Rothová Olga, RNDr., Ph.D. (15.04.2008)
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