SubjectsSubjects(version: 945)
Course, academic year 2023/2024
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Prokaryotic genetics - MB140P13
Title: Genetika prokaryot
Czech title: Genetika prokaryot
Guaranteed by: Department of Genetics and Microbiology (31-140)
Faculty: Faculty of Science
Actual: from 2022
Semester: summer
E-Credits: 3
Examination process: summer s.:oral
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Level: basic
Note: enabled for web enrollment
Guarantor: RNDr. Jaroslav Nunvář, Ph.D.
Teacher(s): RNDr. Jaroslav Nunvář, Ph.D.
Co-requisite : {At least one of the following subjects ((MB140P71, MB140P21, MB140P41)}
Is co-requisite for: MB140C13, MB140C31
Annotation -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (16.05.2023)
Aim of the lecture is to introduce students to fundamentals of prokaryotic genetics. The genetic organization of prokaryotes, means of gene transfer and genetic approaches to study prokaryotes will be covered.

Literature -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (16.05.2023)

Molecular Genetics of Bacteria, Snyder, L. and Champness, W. 2nd Ed., (ASM Press), 2003.

Requirements to the exam
Last update: RNDr. Jaroslav Nunvář, Ph.D. (16.05.2023)

The exam is oral.

Syllabus -
Last update: RNDr. Jaroslav Nunvář, Ph.D. (16.05.2023)

The lectures are given in Czech language only.

1. Genomic organization, replication

2. Transcription, translation

3. Global regulation

4. Transformation, transposition

5. Conjugation

6. Bacteriophages

7. Important genetic elements (integrons, R/M systems, T/A modules, CRISPR-Cas)

8. Mutations

9. Generalized mutagenesis

10. Mapping of mutations, genomics

11. Directed genetic analysis, metagenomics

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