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Last update: VOTRUB (20.03.2003)
as main components of the cytoskeleton. Together with a number of associated, structural and regulatory proteins, they provide the cell with important dynamics, the mechanical support and integrity. Furthermore, exposing a surface comparable in size with the system of cellular membranes the cytoskeleton may directly affect functioning of interacting proteins in a number of cellular processes, e.g. by sequestering of enzymes from their specific targets. Since the cytoskeletal proteins |
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Last update: VOTRUB (20.03.2003)
1) Architecture of eukaryotic cells - introduction, components of the cytoskeleton, conservativity, heterogeneity , modern methods of cytoskeleton studies (biochemical, immunocytochemical, toxins, molecular biology).
2) Microtubules - structure, dynamics and nucleation; organizing centers (MTOC); microtubule assemblies, molecular motors and associated proteins; functions of microtubules.
3) Actin microfilaments - structure and dynamics; actin containing structures; molecular motors and associated proteins; functions of actin microfilaments.
4)Microtubules and associated proteins in plant cells; Acentrosomal nucleation; mitosis and cytokinesis.
5) Role of cytoskeletal proteins in controlling gene expression (e.g. in localized translation and protein trafficking).
6) Signalling and controlling mechanisms of the cytoskeleton organization; role of cytoskeleton in morphogenesis of plants; role of cytoskleton in cellular reactions to biotic or abiotic stress.
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