Physical Organic Chemistry - GDEFCH05

• Title: Physical Organic Chemistry
• Guaranteed by: Department of Organic And Bioorganic Chemistry (16-16120)
• Faculty: Faculty of Pharmacy in Hradec Králové
• Actual: from 2019
• Semester: both
• Points: 0
• E-Credits: 0
• Hours per week, examination: 0/0, Ex [HT]
• Capacity: winter:unknown / unknown (unknown); summer:unknown / unknown (unknown)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Note: course is intended for doctoral students only; enabled for web enrollment; you can enroll for the course in winter and in summer semester
• Guarantor: doc. PharmDr. Jiří Kuneš, CSc.

Annotation

The course extends the knowledge of physical properties of organic compounds and spectral methods. It is focused on intermolecular attractive forces, physical properties related to interactions between molecules of the same structure and physical properties influencing the interactions between molecules of different structures. Another objective of the course is to broaden the knowledge of the students in the methods of structure elucidation based on the absorption of electromagnetic waves (absorption in UV area, visible light area, IR and radiowaves). Particular attention is paid to advanced 1D experiments (APT, DEPT), and both homocorrelated and heterocorrelated (COSY, NOESY) and heterocorelated (HSQC, HMBC) 2D experiments, and their practical applications to structure elucidation of unknown substances.

Last update: Kuneš Jiří, doc. PharmDr., CSc. (24.09.2021)

Course completion requirements

Oral examination

Last update: Kuneš Jiří, doc. PharmDr., CSc. (24.09.2021)

Literature

Obligatory:

• . . In Robert M. Silverstein, Francis X. Webster, David J. Kiemle. Spectrometric Identification of Organic Comnpounds. . : , , s. -. ISBN ISBN 978-0471393..

Last update: prepocet_literatura.php (19.09.2024)

Syllabus

1. Intermolecular attractive forces

2.Physical properties related to interactions between molecules of the same structure

3. Physical properties influencing the interactions between molecules of different structures

4.Absorption of electromagnetic waves

5.¹H-NMR

6.¹³C-NMR

7. Basic 2D-NMR experiments

8. Use of MS in structural analysis of substances

Last update: Kuneš Jiří, doc. PharmDr., CSc. (24.09.2021)