SubjectsSubjects(version: 964)
Course, academic year 2024/2025
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Radiolabelled Biologically Active Substances - GDAFM02
Title: Radioaktivně značené biologicky aktivní látky
Guaranteed by: Department of Biophysics and Physical Chemistry (16-16110)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2024
Semester: both
Points: 0
E-Credits: 0
Examination process: oral
Hours per week, examination: 0/0, Ex [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech
Teaching methods: full-time
Level:  
Note: course is intended for doctoral students only
enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: Mgr. Pavel Bárta, Ph.D.
Annotation -
The subject is focused on the providing of the theoretical information about the preparation, control, preclinical testing, and clinical application of radiolabelled compounds. The basic topics of the subject includes atom structure, types of radioactive decay, the interaction of ionizing radiation with absorbing matter and particularly biological systems, the summary of experimentally and clinically used radionuclides and their production, methods of direct and indirect radiolabelling of biologically active compounds with the emphasis on radiometal complexes, methods of quality control, pharmacopeial requirements on radiopharmaceuticals, and clinical application of biological active radiopharmaceuticals in radiotherapy, radiodiagnosis and theranostics.
Last update: Bárta Pavel, Mgr., Ph.D. (15.08.2023)
Course completion requirements -

The student will have to pass the oral examination when questioned about the gained knowledge in the topic.

Last update: Bárta Pavel, Mgr., Ph.D. (15.08.2023)
Literature -

Obligatory:

  • Sampson, Charles B.. Sampson's textbook of radiopharmacy. London: Pharmaceutical Press, 2011, 725 s. ISBN 978-0-85369-789-3.
  • Reilly, Raymond (ed.). Monoclonal antibody and peptide-targeted radiotherapy of cancer. Hoboken: Wiley, 2010, 624 s. ISBN 978-0-470-24372-5.

Recommended:

  • Kowalsky, Richard J. Falen, Steven W.. Radiopharmaceuticals in nuclear pharmacy and nuclear medicine. Washington, D.C.: American Pharmacists Association, 2011, 741 s. ISBN 978-1-58212-118-5.
  • Tuniz, Claudio. Radioactivity : a very short introduction. Oxford: Oxford University Press, 2012, 154 s. ISBN 978-0-19-969242-2.

Last update: prepocet_literatura.php (19.09.2024)
 
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