Dosage Forms II - GAPS346
Title: Dosage Forms II
Guaranteed by: Department of Pharmaceutical Technology (16-16210)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2024
Semester: winter
Points: 0
E-Credits: 8
Examination process: winter s.:written
Hours per week, examination: winter s.:56/35, C+Ex [HS]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: not taught
Language: English
Teaching methods: full-time
Level:  
Is provided by: GAF346
Note: deregister from the credit exam date if a requisite was not fulfilled
Guarantor: doc. PharmDr. Zdeňka Šklubalová, Ph.D.
Interchangeability : GAPS028
Is interchangeable with: GAPS028, GAPS006
Examination dates   Schedule   
Annotation -
Pharmaceutical technology 2 is focused on specific dosage forms mainly produced in pharmaceutical industry, such as sterile dosage forms, aerodispersion, vaccines, solid dosage forms - tablets, capsules, pellets, etc.). Drug delivery systems with modified release are included. The practical training continues in the evaluation of properties of pharmaceutical products. Seminars improve knowledge of specific methods used in the formulation and/or the evaluation of pharmaceutical preparations.
Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Course completion requirements -

 

For the credit:

 

  • practical training and seminars - 100% presence
  • reports from practical training
  • 75% correct in test

The subject is concluded by passing the exam and it is included in the Final State Examination.

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Literature -

Obligatory:

  • Ranade, Vasant V. Cannon, John B.. Drug delivery systems. Boca Raton: CRC Press, 2011, 590 s. ISBN .

  • Allen, Loyd V. Ansel, Howard C.. Ansel's Pharmaceutical dosage forms and drug delivery systems. Philadelphia: Lippincott William nad Wilkins, 2014, 794 s. ISBN 978-1-4698-5568-4.

  • null. . In Yeo, Yoon (ed.). Nanoparticulate drug delivery systems : strategies, technologies, and applications . Hoboken: Wiley, 2013, s. -. ISBN 978-1-118-14887-7..

  • null. . In Florence, A. T. Siepmann, Jurgen (eds.). Modern pharmaceutics . New York: Informa Healthcare USA, 2009, s. -. ISBN 978-1-4200-6566-4..

  • null. . In Akers, Michael J.. Sterile drug products : formulation, packaging, manufacturing, and quality . New York: Informa Healthcare, 2010, s. -. ISBN 978-084933993-6..

  • null. . In Allen, Loyd V. (ed.). Remington : an introduction to pharmacy . London: Pharmaceutical Press, 2013, s. -. ISBN 978-0-85711-104-3..

  • null. . In Swarbrick, James, (ed.). Encyclopedia of pharmaceutical technology . New York: Informa Healthcare, 2007, s. -. ISBN 0-8493-9399-X..

Last update: prepocet_literatura.php (19.09.2024)
Teaching methods -

lecture

seminar

practical training

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Requirements to the exam -

The confirmation of  credits from SIS

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Syllabus -

1) Dosage Forms

  • Dosage forms and their classification

  • Pharmaceutical excipients

  • Biopharmaceutical principles in dosage forms

  • Pharmaceutical dispersion systems

  • Liquid dosage forms

  • Semisolid dosage forms

  • Solid dosage forms

  • Sterile dosage forms

  • Inhalation preparations

  • Modified release drug delivery systems

  • Targeted drug delivery systems

    2) Manufacturing operations in pharmaceutical technology

  • Water production

  • Filtration

  • Comminution. Milling

  • Mixing. Homogenization

  • Drying, Freeze Drying

  • Sterilization

    3) Quality control and stability of dosage forms

  • Good manufacturing practice

  • Stability of dosage forms.

  • Pharmaceutical packaging

  • Uniformity of dose

  • Disolution tests

  • Granulometry

  • Rheology

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)
Learning resources -

Web FaF:

https://intranet.faf.cuni.cz/Study-materials/KFT/?path=pharmaceutical+technology

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (04.12.2021)