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Course, academic year 2024/2025
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Physical Principles of Dosage Forms - GAPS019
Title: Physical Principles of Dosage Forms
Guaranteed by: Department of Pharmaceutical Technology (16-16210)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2023
Semester: winter
Points: 0
E-Credits: 2
Examination process: winter s.:written
Hours per week, examination: winter s.:28/0, Ex [HS]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Is provided by: GAF308
Note: deregister from the exam date if a requisite was not fulfilled
course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: doc. Dr. Georgios Paraskevopoulos, Ph.D.
Annotation -
Subject Physical Principles of Dosage Forms is taught in the third year of study and builds on Biophysics and Physical Chemistry. The aim of the subject is to provide comprehensive information on the basic physical principles used in formulation, function and stabilizing pharmaceutical forms. In particular, it describes the properties of solid phase (active compounds and Excipients), liquid phase and dispersion (molecular, colloidal and macrodispersion) and interfacial interfacacial phenomena that are related to the physical and chemical stability of pharmaceutical products. In the subject of the Physical Principles of Dosage Forms, students will also be acquainted with the basics of polymer chemistry necessary to understand the structure, properties and function of these substances in pharmaceutical formulations and modern drug delivery systems. The basic principles of pharmaceutical nanotechnologies will also be included. Considering that the physical properties of materials and physical processes at the interface significantly affect resulting quality of pharmaceutical formulations, understanding these principles is essential for further study of pharmaceutical technology and dosage forms. From this perspective, the Physical Principles of Dosage Forms can be viewed as an interdisciplinary subject with a linking function between fundamental subjects taught in the first section of study and highly specialized pharmaceutical technology. Topics: Solution properties, Solid phase, Solid phase properties, Solubility and dissolution, Diffusion, Interfacial phenomena in pharmaceutical Systems, Pharmaceutical surfactants, Pharmaceutical polymers, Polymer systems, Rheology, Dispersion systems and their stability,
Last update: Paraskevopoulos Georgios, doc. Dr., Ph.D. (17.07.2024)
Course completion requirements -

written test

Last update: Paraskevopoulos Georgios, doc. Dr., Ph.D. (17.07.2024)
Literature - Czech

Povinná:

  • Sinko, Patrick J. (ed.). Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences. Philadelphia: Lippicott Williams & Wilkins, 2011, 659 s. ISBN 978-1-60913-402-0.
  • Attwood, D.. Physical pharmacy. London: Pharmaceutical Press, 2012, 218 s. ISBN 978-0-85711-064-0.

Last update: prepocet_literatura.php (19.09.2024)
Syllabus -

Subject Physical Principles of Dosage Forms is taught in the third year of study and builds on Biophysics and Physical Chemistry. The aim of the subject is to provide comprehensive information on the basic physical principles used in formulating and stabilizing pharmaceutical forms. In particular, it describes the properties of the solid phase (active compounds and Excipients), liquid phase and dispersion (molecular, colloidal and macrodispersion) and interfacial phenomena that are related to the physical and chemical stability of pharmaceutical products. In the subject of the Physical Principles of Dosage Forms, students will also be acquainted with the basics of polymer chemistry necessary to understand the structure, properties and function of these substances in pharmaceutical formulations and modern drug delivery systems. The basic principles of pharmaceutical nanotechnologies will also be included. Considering that the physical properties of materials and physical processes at the interface significantly affect the resulting quality of pharmaceutical formulations, understanding these principles is essential for further study of pharmaceutical technology and dosage forms. From this perspective, the Physical Principles of Dosage Forms can be viewed as an interdisciplinary subject with a linking function between fundamental subjects taught in the first section of study and highly specialized pharmaceutical technology. Topics: Solution properties, Solid-phase, Solid-phase properties, Solubility and dissolution, Diffusion, Interfacial phenomena in pharmaceutical Systems, Pharmaceutical surfactants, Pharmaceutical polymers, Polymer systems, Rheology, Dispersion systems and their stability, Nanotechnology.

Last update: Paraskevopoulos Georgios, doc. Dr., Ph.D. (17.07.2024)
Learning resources - Czech

Material from lectures at the study material of faf.cuni.cz

Last update: Paraskevopoulos Georgios, doc. Dr., Ph.D. (17.07.2024)
 
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