Subjects

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Applied Statistics - GAPL005

Title:	Advanced Statistics
Guaranteed by:	Department of Biophysics and Physical Chemistry (16-16110)
Faculty:	Faculty of Pharmacy in Hradec Králové
Actual:	from 2024
Semester:	winter
Points:	0
E-Credits:	2
Examination process:	winter s.:
Hours per week, examination:	winter s.:8/10, C [HS]
Capacity:	unknown / unknown (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	taught
Language:	English
Teaching methods:	full-time
Level:

Guarantor:	doc. Dipl.-Math. Erik Jurjen Duintjer Tebbens, Ph.D.

Examination dates WS schedule

Annotation -

Advanced Statistics deals with the main statistical methods used in pharmaceutical chemistry. The emphasis is on choosing the right type of statistical test and the resulting interpretation of the results. Students will become familiar with statistical functions in specialized software (mainly Prism GraphPad) using concrete examples from pharmaceutical chemistry.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (17.01.2025)

Course completion requirements -

Conditions for granting the credit test – Applied statistics

1. Active participation during all seminars – in the case of absence, a written
excuse by the physician must be handed over.
2. The student must pass the final test in which all tasks must be fulfilled in a
satisfactory way. Every student has at most 3 tries.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (03.01.2025)

Literature -

Recommended:

Klemera, Petr, Klemerová, Věra. Základy aplikované statistiky pro studující farmacie. Praha: Karolinum, 1999, 84 s. ISBN 80-7184-888-3.

. . In Box, George E. P., Hunter, J. Stuart, Hunter, William Gordon. Statistics for experimenters : design, innovation, and discovery . Hoboken, N.J.: Wiley-Interscience, 2005, s. -. ISBN 0-471-71813-0..

Li Wan Po, Alain. Statistics for pharmacists. London: Blackwell Sci., 1997, 252 s. ISBN 0-632-04881-6.

Zvára, Karel. Biostatistika. Praha: Karolinum, 2003, 213 s. ISBN 80-246-0739-5.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (17.01.2025)

Teaching methods -

The guarantor lectures, teachers conduct seminars. Consultation may be based on a personal, telephone or email order.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (17.01.2025)

Requirements to the exam -

The subject does not end with an exam.

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (17.01.2025)

Syllabus -

- descriptive statistics for quantitative and qualitative data and their visualization

- normal and lognormal distribution, tests of (log)normality, qq-plots

- curve fitting for nonlinear agonist/inhibitor models

- simple and multiple linear regression

- simple and multiple logistic regression

- survival analysis

- t-tests and nonparametric counterparts

- ANOVA, one- and two-way and nonparametric counterparts

- Chi-square and exact Fisher test

- Correlation coefficient and autocorrelation

Last update: Duintjer Tebbens Erik Jurjen, doc. Dipl.-Math., Ph.D. (17.01.2025)