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Course, academic year 2025/2026
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Extemporaneous Preparation in Hospital Pharmacy - GAF327
Title: Extemporaneous Preparation in Hospital Pharmacy
Guaranteed by: Department of Pharmaceutical Technology (16-16210)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2021 to 2025
Semester: summer
Points: 0
E-Credits: 4
Examination process: summer s.:combined
Hours per week, examination: summer s.:0/40, C+Ex [HS]
Capacity: unknown / unknown (3)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: doc. PharmDr. Zdeňka Šklubalová, Ph.D.
Co-requisite : GAF346
Interchangeability : GAF289
Is interchangeable with: GAF289
Annotation -
An optional course in the 4th year of pharmacy studies.<br> The course follows the course Pharmaceutical Technology I and II. It is intended for students who want to expand their knowledge in the field of hospital preparation of drugs and specialize in working in a hospital pharmacy. The main goal is knowledge of hospital preparation, especially the preparation of pediatric preparations, sterile preparations (ophthalmic and parenteral) and the production of cytostatic preparations.<br> The course includes a one-day visit to a hospital pharmacy (in Hradec Králové).<br> The capacity is limited to 3 students.<br>
Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Course completion requirements -

100% presence in lectures/seminars and training.

The credit test: ≥75% correct answers in test/tasks is necessary

The course ends with an exam.
Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Literature -

Obligatory:

  • -. European Pharmacopoeia 9.0. Strassbourg: , 2017, s. ISBN .
  • . . In Allen, Loyd V.. Pharmaceutical dosage forms and drug delivery systems . Philadelphia: Wolters Kluwer, 2018, s. -. ISBN 978-1-4963-7291-8..
  • . . In Allen, Loyd V.. The art, science, and technology of pharmaceutical compounding . Washington, D.C.: American Pharmacists Association, 2012, s. -. ISBN 978-1-58212-164-2..

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Teaching methods -

lecture

seminar

training

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Requirements to the exam -

100% presence at theoretical and practical training

Seminar work/tasks

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Syllabus -

• Specifics of hospital preparation of LP

• Preparation of pediatric preparations, IPL

• Preparation of sterile preparations – principles

• Preparation of sterile preparations – infusion and injection preparations

• Preparation of sterile preparations – parenteral nutrition, AIO

• Preparation of sterile preparations – specific isotonization procedures

• Central preparation of cytostatics

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Learning resources -

Moodle kurz: Nemocniční příprava léčivých přípravků https://dl1.cuni.cz/enrol/index.php?id=2907

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
Learning outcomes -

The course builds on the knowledge and skills acquired in the subjects Pharmaceutical Technology I and II.

After completing the course, students will be able to use the following terms (including their commonly used abbreviations): clean rooms, aseptic work, preparation of sterile products, individual preparation of medicinal products, preparation of cytostatics, risk management, validation parameters of sterilization, cryoscopic value, chloride equivalent, isotonic adjustment, buffering, parenteral nutrition, CAN, calcium phosphate product (CaP), AIO, osmolarity

Learning outcomes:

Based on the knowledge and skills acquired, the student will:

• describe the structure of a hospital pharmacy

• explain the specifics of hospital preparation of non-sterile and sterile medicinal products, including pediatric preparations

• explain the requirements for the preparation of cytostatic and other hazardous drugs

• discuss the requirements for individual preparation of medicinal products

• discuss the risks in the preparation of medicinal products (risk management)

• discuss the principles of adjusting the composition of ophthalmic and parenteral preparations, including infusions for parenteral nutrition

• be able to practically adjust the composition of eye drops, calculate the CAN, CaP value and osmolarity of a parenteral preparation (mixture)

• be able to propose a suitable procedure for preparing medicinal products according to a prescription, evaluate the compatibility/incompatibility between components and practically prepare a medicinal product

• discuss the validation parameters of sterilization, be able to calculate the validated sterilization time

Last update: Šklubalová Zdeňka, doc. PharmDr., Ph.D. (30.07.2025)
 
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