Cellular Pathobiochemistry - FV054

• Title: Cellular Pathobiochemistry
• Guaranteed by: Department of Medical Biochemistry (15-180)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2023
• Semester: winter
• Points: 0
• E-Credits: 1
• Examination process: winter s.:
• Hours per week, examination: winter s.:15/0, C [HS]
• Capacity: 30
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: doc. RNDr. Radim Havelek, Ph.D.
• Comes under: Dentistry - ELECTIVE subjects; Dentistry - ELECTIVE subjects (2019->; General medicine - ELECTIVE subjects
• Pre-requisite : {Maláskup. Bch I a dBch II}
• Incompatibility : FG50036
• Interchangeability : FG50036
• Is incompatible with: FG50036
• Is interchangeable with: FG50036

Annotation

Last update: doc. MUDr. Alena Stoklasová, CSc. (04.09.2023)

The aim of this subject is to provide deeper insight into the intracellular events and signalling involved in cell death and proliferation, cell damage induction and prevention/response and related regulatory events on molecular level. The knowledge is applied to carcinogenesis, diagnostics and treatment of cancers.

Requirements to the exam

Last update: doc. MUDr. Alena Stoklasová, CSc. (04.09.2023)

Credit:

Attendance - one absence is tolerated.  Credit test: focused on topics discussed in lectures.

Syllabus

Last update: doc. MUDr. Alena Stoklasová, CSc. (04.09.2023)

Lecturers:

• prof. PharmDr. Emil Rudolf, Ph.D.
• prof. MUDr. Martina Řezáčová, Ph.D.
• doc. MUDr. Alena Stoklasová, CSc.
• doc. RNDr. Radim Havelek, Ph.D.
• RNDr. Jana Nekvindová, Ph.D.

Lectures:

1. Oxidative stress. 
2. Pathobiology of cell death, intracellular communication.   
3. Cell cycle and programmed cell death.
4. Cellular strategy in response to DNA damage.
5. Epigenetics. Credit test.

Literature

Last update: doc. MUDr. Alena Stoklasová, CSc. (04.09.2023)

Synopsis of lectures: http://moodle.lfhk.cuni.cz/moodle2/course/index.php?categoryid=15