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Course, academic year 2023/2024
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Pathological Anatomy I - FDP024
Title: Pathological Anatomy I
Guaranteed by: The Fingerland Department of Pathology (15-490)
Faculty: Faculty of Medicine in Hradec Králové
Actual: from 2020
Semester: summer
Points: 0
E-Credits: 6
Examination process: summer s.:
Hours per week, examination: summer s.:45/42, C [HS]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: prof. MUDr. Jan Laco, Ph.D.
Pre-requisite : {Dentistry 1st year}
Incompatibility : FZ10022
Interchangeability : FA0204039, FZ10022
Is pre-requisite for: FDP027
In complex pre-requisite: FDP045, FDP046, FDP047, FDP048, FDP049, FDP050, FDP051, FDP052, FDP053, FDP054, FDP055, FDP056, FDP057, FDP058, FDP059, FDP060, FDP061, FDP062, FD10048
Annotation
Last update: Bc. Michaela Žáková (09.01.2023)
Annotation: Pathological anatomy is part of basic study subjects. It introduces students to the nature of human diseases, the cause of diseases (etiology), the mechanisms of their development (pathogenesis) and the changes in cells and tissues caused by the disease state (morphology of diseases). Introduction; cell injury; adaptation; inflammation; repair; regeneration; circulatory disorders; shock; genetic diseases; immune system; environmental diseases; infectious diseases; oncology; heart; blood vessels; hematopoietic system; respiratory system; gastrointestinal system; liver; biliary system; pancreas; kidney; urinary tract.
Entry requirements
Last update: Bc. Michaela Žáková (09.01.2023)
Entry requirements: 0
Aim of the course
Last update: Bc. Michaela Žáková (09.01.2023)

The aim of the course:

The course pathological anatomy I includes general pathology and part of special (organ) pathology. The aim of general pathology is to acquaint students with the basic mechanisms of cell and tissue damage, with the basic aspects of the inflammatory reaction and with the general characteristics of cancer. The aim of special pathology is to acquaint students with etiopathogenesis, morphology, clinical manifestations and complications of the most important diseases of the cardiovascular system, respiratory system, hematological system, gastrointestinal system and urogenital system.

Requirements to the exam
Last update: Bc. Michaela Žáková (09.01.2023)

Conditions for granting pathology credit in summer term:

Credit examination takes place on the last two pathology practical classes, in the period from 18 to 25 May 2023.

The basic condition for granting the credit is participation in practical classes (one absence is accepted; each absence must be announced before the beginning of the class by e-mail to the teacher). More than one absence must be replaced in a way agreed with the assistant teacher. Oral part of the credit is based in the diagnosis of one to two microscopic slides and verification of knowledge of the relevant theory.

For credit there are one regular and 2 additional terms. The credit is tested generally by the assistant professor of the group.

 

Syllabus
Last update: Bc. Michaela Žáková (01.02.2023)

Sylabus:

Lecturers

• Kateřina Kamarádová, MD, PhD

• Petra Kašparová, MD, PhD

• Prof. Jan Laco, MD, PhD

• Prof. Aleš Ryška, MD, PhD

• Václav Stejskal, MD

 

Lectures

1.     Introduction. Cell pathology - cell injury, adaptation – Lecture on-line (prof. Ryška 3, hours)

2.     Introduction. Cell pathology - cell injury, adaptation- Lecture on-line (prof. Ryška, 3 hours)

3.     Inflammation, repair, regeneration (prof. Laco, 3 hours)

4.     Circulatory disorders, shock (prof. Laco, 3 hours)

5.     Genetic diseases. (prof. Laco, 3 hours)

6.     Immune system – Lecture on-line (prof. Laco, 3 hours)

7.     Infectious diseases (prof. Laco, 3 hours)

8.     Environmental diseases (dr. Kamarádová, 3 hours)

9.     Neoplasia I. (prof. Ryška, 3 hours)

10.   Neoplasia II. (prof. Ryška, 3 hours)

11.   Liver. Biliary system. Pancreas (prof. Laco, 3 hours)

12.   Respiratory system (prof. Laco, 3 hours)

13.   Gastrointestinal system (prof. Laco, 3 hours)

14.   Heart, blood vessels (dr. Stejskal, 6 hours)

15.   Kidney, urinary tract (prof. Laco, 3 hours)

16.   Hematopoietic system (dr. Kašparová, 3 hours)

 

Practical courses & seminars:

Lecturers

Kateřina Kamarádová, MD, PhD

Thursday, 15.2. – 17.5. 2023

 

Practical courses

1.     General pathology: Kidney infarction (1). Myocardial infarction (3). Post-myocardial infarction scar (4, 4B). Acute pancreatic necrosis (6). Brain infarction (7). Caseous necrosis, adrenal gland (10).

2.     General pathology: Lipomatous atrophy, pancreas (11). Steatosis, liver (24, 24B). Amyloidosis, kidney (29, 29B, 29C). Metastatic calcification, lung (42, 42B).

3.     General pathology: Fibrocystic changes of breast (50). Polycystic ovary (51). Polycystic kidney disease - adult type (48A). Gaucher´s disease, spleen (26). Purulent inflammation, neck (74).

4.     Disorders of circulation: Phlebothrombosis (57). Chronic pulmonary thrombembolism (58B). Lung edema (64). Chronic lung congestion (54, 54B). Chronic liver congestion (53).

5.     Pathology of heart and vessels: Myocardial hypertrophy (65). Infective endocarditis (84). Rheumatic myocarditis (109A). Fibrinous pericarditis (71). Aortic atheroma (32).

6.     Pathology of respiratory tract: Bronchopneumonia (81). Miliary tuberculosis of lung (98). DAD - acute phase (178). Squamous cell carcinoma of lung (160). Small cell carcinoma of lung (161).

7.     Pathology of gastrointestinal tract: Chronic gastritis (192, 192B). Chronic peptic ulcer of stomach (78). Suppurative appendicitis (77). Crohn's disease (193). Colonic adenocarcinoma (157). Liver cirrhosis (92, 92B).

8.     Pathology of urinary tract: Acute pyelonephritis (90). Renal pelvis papillocarcinoma (144). Carcinoma of kidney (168, 168B). Pathology of CNS: Purulent meningitis (73). Multiple sclerosis (119, 119B).

9.     Pathology of genital tract: Testicular seminoma (174). Prostatic nodular hyperplasia (120). Ovarian teratoma (170). Extrauterine gravidity, fallopian tube (67). Hydatidiform mole (172).

10.   Pathology of genital tract: Leiomyoma, uterus (129). Squamous cell carcinoma, uterine cervix (159). Condyloma acuminatum (143). Fibroadenoma, breast (150). Invasive ductal breast carcinoma (155).

11.   Hematopathology: Hodgkin´s lymphoma (135). Non-Hodgkin´s lymphoma (136). Chronic myeloid leukemia, liver (137). Myeloma, vertebra (189).

12.   Autopsy.

13.   Revision seminar.

14.   Credit.

Literature
Last update: Bc. Michaela Žáková (09.01.2023)

Compulsory literature:

1.       Zámečník J. et al.: Patologie. Praha, LD, s.r.o. - Prager Publishing, 2019.  ISBN 978-80-270-6457-1

2.       Kumar v, Abbas AK, Aster JC: Robbins Basic Pathology. 9. vyd. Elsevier, 2013. ISBN 978-1437717815.

3.       Odell, E.W.: Cawson´s Essentials of Oral Pathology and Oral Medicine. 9th ed., Elsevier, 2017. ISBN 978-0-7020-4982-8

 

Recommended literature:

1.       Povýšil C., Šteiner I. et al.: Obecná patologie. Praha, Galén, 2011. EAN 9788072627738

2.       Povýšil C., Šteiner I. et al.: Speciální patologie. Praha, Galén, 2007. EAN 9788072624942

3.       Slezák R, Dřízhal I: Atlas chorob ústní sliznice. Praha, Quintessenz, 2004. ISBN 80-903181-5-0

 
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