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Course, academic year 2024/2025
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Current Issues in Pharmacology - EAV10001
Title: Current issues in Pharmacology
Guaranteed by: Ústav farmakologie (14-100)
Faculty: Faculty of Medicine in Pilsen
Actual: from 2022
Semester: summer
Points: 4
E-Credits: 4
Examination process: summer s.:
Hours per week, examination: summer s.:12/6, C [HS]
Capacity: unknown / unknown (50)
Min. number of students: 5
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
For type:  
Note: course can be enrolled in outside the study plan
Guarantor: prof. PharmDr. Radek Kučera, Ph.D.
PharmDr. Bc. Eva Dědečková
MUDr. Michal Jirásko
Comes under: Volitelné předměty, 2. ročník AVSEOB
Volitelné předměty, 2. ročník AVSEOB20
Volitelné předměty, 2. ročník AZUB18
Volitelné předměty, 3. ročník AVSEOB
Volitelné předměty, 3. ročník AVSEOB20
Volitelné předměty, 3. ročník AZUB.L.
Volitelné předměty, 4. ročník AVSEOB20
Volitelné předměty, 5. ročník AVSEOB
Annotation - Czech

The course Current Issues in Pharmacology follows the basic 2-semester pharmacology. During the semester, students will focus on chapters that did not fit into basic pharmacology and are currently undergoing rapid development. At the same time, the orientation to clinical practice is remembered - students will practice already acquired theoretical knowledge and their application in solving clinical cases in a special course in MOODLE.

At the same time, students will participate in laboratory examination of vitamin D blood levels, monitoring the effectiveness of its supplementation and evaluation of its quality.


Syllabus
1. Vitamin D - only a trending topic? (or will be something on it…?)
Basic concepts, discovery, and history of the use of vitamin D. The beginnings of the use of the effects of vitamin D - solar and UV therapy. Vitamin D metabolism, reference values. Vitamin D and the immune system. Use of vitamin D in sports.
Blood draw and determination of vitamin D levels (for volunteers). Correspondence assessment of vitamin D levels and supplementation using cholecalciferol. Taking cholecalciferol for 1 month, then a second blood draw.

prof. PharmDr. Radek Kučera, Ph.D.


2. Drugs and media
Rules for the promotion of medical products, medical products, and food supplements. Nutrition and health claims - conditions of their use. How the law is commonly circumvented in advertising and what consequences it brings for patients.

PharmDr. and Bc. Eva Dědečková, MUDr. Michal Jirásko


3. New synthetic drugs (designer drugs)
How are drug manufacturers trying to get ahead of the law? Which distribution channels do new drugs move through? The way designer drugs change the drug scene and what risks and the potential they bring.

MUDr. Michal Jirásko , PharmDr. Eva Dědečková

History. Law. Basic groups - Psychedelics, dissociative drugs, empathogens, stimulants, sedatives, GHB analogues, and synthetic cannabinoids - products, nomenclature, use, toxicity, examples of abuse, legislative measures.


4. Food supplements
Differences between medicinal products and dietary supplements. Can dietary supplements be hazardous? Examples of dangerous or potentially risky food supplements on the market. How to choose the right and high-quality dietary supplement. How to make your own dietary supplement. How to register and place a dietary supplement on the market.

PharmDr. Eva Dědečková, MUDr. Michal Jirásko


5. Toxicology of pollutants - environmental toxicology
New and emerging pollutants. What we drink, eat, and breathe without knowing well the long-term effects on our health. Possible inevitable consequences of human production on living organisms.

MUDr. Michal Jirásko , PharmDr. Eva Dědečková


6. Vitamin D - evaluation
Evaluation of measured vitamin D levels, evaluation of supplementation success.
Supplementation models, calculation of the loading dose. Risks associated with hypovitaminosis.

prof. PharmDr. Radek Kučera, Ph.D.
Last update: Kučera Radek, prof. PharmDr., Ph.D. (08.06.2021)
Literature - Czech

Rang & Dale´s Pharmacology, 9th edition, 2020, Elsevier Ltd.

Bertram Katzung, Basic and Clinical Pharmacology, 14th Edition, Lange

Casarett and Doull's Toxicology: The Basic Science of Poisons, 9th Edition, McGraw-Hill Professional Pub

Work with scientific literature - journals in clinical pharmacology.

Last update: Dědečková Eva, PharmDr. Bc. (21.05.2021)
Requirements to the exam - Czech

Participation in seminars and elaboration of case studies.

Last update: Dědečková Eva, PharmDr. Bc. (21.05.2021)
 
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